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A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

Cell, 2010-04, Vol.141 (1), p.69-80

2010

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Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure

Cancer cell, 2017-08, Vol.32 (2), p.221-237.e13

2017

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Hypoxia-induced down-regulation of BRCA1 expression by E2Fs

Cancer research (Chicago, Ill.), 2005-12, Vol.65 (24), p.11597-11604

2005

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Mass Spectrometric Quantification of Histone Post-translational Modifications by a Hybrid Chemical Labeling Method[S]

Molecular & cellular proteomics, 2015-04, Vol.14 (4), p.1148-1158

2015

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A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2'-Deoxycytidine

Cancer research (Chicago, Ill.), 2018-03, Vol.78 (5), p.1127-1139

2018

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An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition

PloS one, 2016-11, Vol.11 (11), p.e0166438-e0166438

2016

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Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors

Cancer research (Chicago, Ill.), 2008-05, Vol.68 (9), p.3389-3395

2008

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Disrupting Mechanisms that Regulate Genomic Repeat Elements to Combat Cancer and Drug Resistance

Frontiers in cell and developmental biology, 2022-05, Vol.10, p.826461-826461

2022

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Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer

Cell reports (Cambridge), 2024-02, Vol.43 (2), p.113684-113684, Article 113684

2024

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Chk1 and Claspin potentiate PCNA ubiquitination

Genes & development, 2008-05, Vol.22 (9), p.1147-1152

2008

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Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs

Nature communications, 2016-08, Vol.7 (1), p.12351-12351, Article 12351

2016

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A common signaling cascade may underlie “addiction” to the Src, BCR-ABL, and EGF receptor oncogenes

Cancer cell, 2006-11, Vol.10 (5), p.425-435

2006

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Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit

Nature cell biology, 2007-02, Vol.9 (2), p.225-232

2007

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Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide

Molecular cancer therapeutics, 2008-11, Vol.7 (11), p.3575-3585

2008

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Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies

Bioorganic & medicinal chemistry letters, 2016-08, Vol.26 (16), p.4036-4041

2016

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Proceedings of the inaugural Dark Genome Symposium: November 2022

Mobile DNA, 2023-11, Vol.14 (1), p.18-13, Article 18

2023

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Nuclear organization of DNA replication in primary mammalian cells

Genes & development, 2000-11, Vol.14 (22), p.2855-2868

2000

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Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia

The Journal of cell biology, 2017-11, Vol.216 (11), p.3535-3549

2017

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Opposing Roles of pRB and p107 in Adipocyte Differentiation

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (20), p.10826-10831

2000

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The retinoblastoma tumour suppressor in development and cancer

Nature reviews. Cancer, 2002-12, Vol.2 (12), p.910-917

2002

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The Retinoblastoma Protein Is Required for Ras-Induced Oncogenic Transformation

Molecular and Cellular Biology, 2006-02, Vol.26 (4), p.1170-1182

2006

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Modulation of CREB Activity by the Rho GTPase Regulates Cell and Organism Size during Mouse Embryonic Development

Developmental cell, 2002-05, Vol.2 (5), p.553-565

2002

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Combinatorial Roles for pRB, p107, and p130 in E2F-Mediated Cell Cycle Control

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (20), p.10820-10825

2000

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Proline Starvation Induces Unresolved ER Stress and Hinders mTORC1-Dependent Tumorigenesis

Cell metabolism, 2016-11, Vol.24 (5), p.753-761

2016

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A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations

An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells

Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure

Hypoxia-induced down-regulation of BRCA1 expression by E2Fs

Mass Spectrometric Quantification of Histone Post-translational Modifications by a Hybrid Chemical Labeling Method[S]

A KDM5 Inhibitor Increases Global H3K4 Trimethylation Occupancy and Enhances the Biological Efficacy of 5-Aza-2'-Deoxycytidine

An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition

Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors

Disrupting Mechanisms that Regulate Genomic Repeat Elements to Combat Cancer and Drug Resistance

Retroelement decay by the exonuclease XRN1 is a viral mimicry dependency in cancer

Chk1 and Claspin potentiate PCNA ubiquitination

Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs

A common signaling cascade may underlie “addiction” to the Src, BCR-ABL, and EGF receptor oncogenes

Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit

Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide

Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies

Proceedings of the inaugural Dark Genome Symposium: November 2022

Nuclear organization of DNA replication in primary mammalian cells

Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia

Opposing Roles of pRB and p107 in Adipocyte Differentiation

The retinoblastoma tumour suppressor in development and cancer

The Retinoblastoma Protein Is Required for Ras-Induced Oncogenic Transformation

Modulation of CREB Activity by the Rho GTPase Regulates Cell and Organism Size during Mouse Embryonic Development

Combinatorial Roles for pRB, p107, and p130 in E2F-Mediated Cell Cycle Control

Proline Starvation Induces Unresolved ER Stress and Hinders mTORC1-Dependent Tumorigenesis

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