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Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity

The international journal of neuropsychopharmacology, 2018-10, Vol.21 (10), p.962-977

2018

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Functional selectivity and classical concepts of quantitative pharmacology

The Journal of pharmacology and experimental therapeutics, 2007-01, Vol.320 (1), p.1-13

2007

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Atypical antipsychotics and inverse agonism at 5-HT2 receptors

Current pharmaceutical design, 2015-01, Vol.21 (26), p.3732

2015

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Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

eLife, 2017-11, Vol.6

2017

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Fine-tuning serotonin2c receptor function in the brain: molecular and functional implications

Neuropharmacology, 2008-11, Vol.55 (6), p.969-976

2008

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Long‐term antagonism and allosteric regulation of mu opioid receptors by the novel ligand, methocinnamox

Pharmacology research & perspectives, 2021-12, Vol.9 (6), p.e00887-n/a

2021

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Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.1054

2007

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Transition of microbial communities and degradation pathways in anaerobic digestion at decreasing retention time

New biotechnology, 2021-01, Vol.60, p.52-61

2021

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Physiological relevance of constitutive activity of 5-HT2A and 5-HT2C receptors

Trends in pharmacological sciences (Regular ed.), 2005-12, Vol.26 (12), p.625-630

2005

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Organic waste biorefineries: Looking towards implementation

Waste management (Elmsford), 2020-08, Vol.114, p.274-286

2020

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A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling

The Journal of pharmacology and experimental therapeutics, 2008-03, Vol.324 (3), p.1084

2008

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Characterization of Buprenorphine Antagonism at Human Mu Opioid Receptors

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Structure of a cellulose degrading bacterial community during anaerobic digestion

Biotechnology and bioengineering, 2005-12, Vol.92 (7), p.871-878

2005

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Concurrent microscopic observations and activity measurements of cellulose hydrolyzing and methanogenic populations during the batch anaerobic digestion of crystalline cellulose

Biotechnology and bioengineering, 2005-08, Vol.91 (3), p.369-378

2005

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Rapid digestion of shredded MSW by sequentially flooding and draining small landfill cells

Waste management (Elmsford), 2016-09, Vol.55, p.12-21

2016

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Ligand‐Dependent Reversal Kinetics of Mu Opioid Receptor Agonists by the Novel Antagonist, Methocinnamox

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Bioremediation for Acid Mine Drainage: Organic Solid Waste as Carbon Sources For Sulfate-Reducing Bacteria: A Review

Journal of Mechanical Engineering and Sciences, 2013-12, Vol.5, p.569-581

2013

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Pilot scale evaluation of a model to distinguish the rates of simultaneous anaerobic digestion, composting and methane oxidation in static waste beds

Waste management (Elmsford), 2018-01, Vol.71, p.156-163

2018

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Removal of sulfate from high-strength wastewater by crystallisation

Water research (Oxford), 2009-02, Vol.43 (3), p.762-772

2009

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Age-related changes in peripheral nociceptor function

Neuropharmacology, 2022-09, Vol.216, p.109187-109187, Article 109187

2022

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G protein-coupled Receptor 30 (GPR30) Forms a Plasma Membrane Complex with Membrane-associated Guanylate Kinases (MAGUKs) and Protein Kinase A-anchoring Protein 5 (AKAP5) That Constitutively Inhibits cAMP Production

The Journal of biological chemistry, 2014-08, Vol.289 (32), p.22117-22127

2014

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RNA‐editing of the 5‐HT2C receptor alters agonist‐receptor‐effector coupling specificity

British journal of pharmacology, 2001-09, Vol.134 (2), p.386-392

2001

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Methodology to determine the extent of anaerobic digestion, composting and CH4 oxidation in a landfill environment

Waste management (Elmsford), 2018-06, Vol.76, p.364-373

2018

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A mass balance model to estimate the rate of composting, methane oxidation and anaerobic digestion in soil covers and shallow waste layers

Waste management (Elmsford), 2017-05, Vol.63, p.196-202

2017

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What's for Lunch at the Conformational Cafeteria?

Molecular pharmacology, 2005-06, Vol.67 (6), p.1819-1821

Clarke, William P

2005

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Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity

Functional selectivity and classical concepts of quantitative pharmacology

Atypical antipsychotics and inverse agonism at 5-HT2 receptors

Pharmacological augmentation of nicotinamide phosphoribosyltransferase (NAMPT) protects against paclitaxel-induced peripheral neuropathy

Fine-tuning serotonin2c receptor function in the brain: molecular and functional implications

Long‐term antagonism and allosteric regulation of mu opioid receptors by the novel ligand, methocinnamox

Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors

Transition of microbial communities and degradation pathways in anaerobic digestion at decreasing retention time

Physiological relevance of constitutive activity of 5-HT2A and 5-HT2C receptors

Organic waste biorefineries: Looking towards implementation

A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling

Characterization of Buprenorphine Antagonism at Human Mu Opioid Receptors

Structure of a cellulose degrading bacterial community during anaerobic digestion

Concurrent microscopic observations and activity measurements of cellulose hydrolyzing and methanogenic populations during the batch anaerobic digestion of crystalline cellulose

Rapid digestion of shredded MSW by sequentially flooding and draining small landfill cells

Ligand‐Dependent Reversal Kinetics of Mu Opioid Receptor Agonists by the Novel Antagonist, Methocinnamox

Bioremediation for Acid Mine Drainage: Organic Solid Waste as Carbon Sources For Sulfate-Reducing Bacteria: A Review

Pilot scale evaluation of a model to distinguish the rates of simultaneous anaerobic digestion, composting and methane oxidation in static waste beds

Removal of sulfate from high-strength wastewater by crystallisation

Age-related changes in peripheral nociceptor function

G protein-coupled Receptor 30 (GPR30) Forms a Plasma Membrane Complex with Membrane-associated Guanylate Kinases (MAGUKs) and Protein Kinase A-anchoring Protein 5 (AKAP5) That Constitutively Inhibits cAMP Production

RNA‐editing of the 5‐HT2C receptor alters agonist‐receptor‐effector coupling specificity

Methodology to determine the extent of anaerobic digestion, composting and CH4 oxidation in a landfill environment

A mass balance model to estimate the rate of composting, methane oxidation and anaerobic digestion in soil covers and shallow waste layers

What's for Lunch at the Conformational Cafeteria?

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