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Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2( 1H )-quinolinones through a Myc-dependent pathway

Cancer letters, 2009-02, Vol.274 (2), p.243-249

2009

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Subtractive immunization using highly metastatic human tumor cells identifies SIMA135 CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen

Oncogene, 2003-03, Vol.22 (12), p.1783-1794

2003

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Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis

Cancer research (Chicago, Ill.), 2004-11, Vol.64 (22), p.8208-8212

2004

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Myc-mediated transformation: the repression connection

Oncogene, 1999-05, Vol.18 (19), p.2925-2933

1999

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Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis

Genes & development, 1998-12, Vol.12 (24), p.3803-3808

1998

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One-week 96-well soft agar growth assay for cancer target validation

BioTechniques, 2004-05, Vol.36 (5), p.826-833

2004

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The c-Myc Transactivation Domain Is a Direct Modulator of Apoptotic versus Proliferative Signals

Molecular and Cellular Biology, 2000-06, Vol.20 (12), p.4309-4319

2000

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Disruption of Myc-Tubulin Interaction by Hyperphosphorylation of c-Myc during Mitosis or by Constitutive Hyperphosphorylation of Mutant c-Myc in Burkitt's Lymphoma

Molecular and Cellular Biology, 2000-07, Vol.20 (14), p.5276-5284

2000

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A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (17), p.9498-9503

2000

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Synthesis, SAR and biological evaluation of 1,6-disubstituted-1H-pyrazolo[3,4-d]pyrimidines as dual inhibitors of Aurora kinases and CDK1

Bioorganic & medicinal chemistry letters, 2012-03, Vol.22 (5), p.2070-2074

2012

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Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors

Bioorganic & medicinal chemistry letters, 2012-06, Vol.22 (12), p.4033-4037

2012

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Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: Structure–activity relationships of the 4-anilino group

Bioorganic & medicinal chemistry, 2006-12, Vol.14 (23), p.7761-7773

2006

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Discovery and structure-activity relationship of N-phenyl-1H-pyrazolo[3,4-b]quinolin-4-amines as a new series of potent apoptosis inducers

Bioorganic & medicinal chemistry, 2008, Vol.16 (1), p.222-231

2008

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Discovery and structure–activity relationship of N-phenyl-1 H-pyrazolo[3,4- b]quinolin-4-amines as a new series of potent apoptosis inducers

Bioorganic & medicinal chemistry, 2008, Vol.16 (1), p.222-231

2008

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A Role for Transcriptional Repression of p21CIP1by c-Myc in Overcoming Transforming Growth Factor β -Induced Cell-Cycle Arrest

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (17), p.9498-9503

2000

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A role for transcriptional repression of p21 CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (17), p.9498-9503

2000

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Molecular analysis of DNA binding and transrepression by c -Myc and regulation of c-Myc-dependent proliferation and apoptosis by phosphorylation

Claassen, Gisela Froelich

2000

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The relation of a cerebrospinal fluid profile associated with Alzheimer's disease with cognitive function and neuropsychiatric symptoms in sporadic cerebral amyloid angiopathy

Alzheimer's research & therapy, 2024-05, Vol.16 (1), p.99-12, Article 99

2024

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Selective activation of apoptosis by a novel set of 4-aryl-3-(3-aryl-1-oxo-2-propenyl)-2( 1H )-quinolinones through a Myc-dependent pathway

Subtractive immunization using highly metastatic human tumor cells identifies SIMA135 CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen

Nuclear hormone receptor NR4A2 is involved in cell transformation and apoptosis

Myc-mediated transformation: the repression connection

Transactivation-defective c-MycS retains the ability to regulate proliferation and apoptosis

One-week 96-well soft agar growth assay for cancer target validation

The c-Myc Transactivation Domain Is a Direct Modulator of Apoptotic versus Proliferative Signals

Disruption of Myc-Tubulin Interaction by Hyperphosphorylation of c-Myc during Mitosis or by Constitutive Hyperphosphorylation of Mutant c-Myc in Burkitt's Lymphoma

A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest

Synthesis, SAR and biological evaluation of 1,6-disubstituted-1H-pyrazolo[3,4-d]pyrimidines as dual inhibitors of Aurora kinases and CDK1

Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors

Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: Structure–activity relationships of the 4-anilino group

Discovery and structure-activity relationship of N-phenyl-1H-pyrazolo[3,4-b]quinolin-4-amines as a new series of potent apoptosis inducers

Discovery and structure–activity relationship of N-phenyl-1 H-pyrazolo[3,4- b]quinolin-4-amines as a new series of potent apoptosis inducers

A Role for Transcriptional Repression of p21CIP1by c-Myc in Overcoming Transforming Growth Factor β -Induced Cell-Cycle Arrest

A role for transcriptional repression of p21 CIP1 by c-Myc in overcoming transforming growth factor β-induced cell-cycle arrest

Molecular analysis of DNA binding and transrepression by c -Myc and regulation of c-Myc-dependent proliferation and apoptosis by phosphorylation

The relation of a cerebrospinal fluid profile associated with Alzheimer's disease with cognitive function and neuropsychiatric symptoms in sporadic cerebral amyloid angiopathy

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