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Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.767-772

2013

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Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-[gamma]

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (3), p.767-772

2013

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Abstract 10067: A Nitric Oxide Donor Binds to SARS-CoV-2 Papain-Like Protease with Therapeutic Implications

Circulation (New York, N.Y.), 2021-11, Vol.144 (Suppl_1)

2021

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Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine

Analytical chemistry (Washington), 2011-06, Vol.83 (11), p.4228-4236

2011

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Novel nitric oxide donors are coronary vasodilators that also bind to the papain-like protease of SARS-CoV-2

Biomedicine & pharmacotherapy, 2024-04, Vol.173, p.116378-116378, Article 116378

2024

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Difluoromethylene at the γ‑Lactam α‑Position Improves 11-Deoxy-8-aza-PGE1 Series EP4 Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE1 Analog (KMN-159) as a Potent EP4 Agonist

Journal of medicinal chemistry, 2019-05, Vol.62 (9), p.4731-4741

2019

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Novel amide and imidazole compounds as potent hematopoietic prostaglandin D 2 synthase inhibitors

Bioorganic & medicinal chemistry letters, 2021-02, Vol.34, p.127759

2021

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Novel amide and imidazole compounds as potent hematopoietic prostaglandin D2 synthase inhibitors

Bioorganic & medicinal chemistry letters, 2021-02, Vol.34, p.127759-127759, Article 127759

2021

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Difluoromethylene at the γ-Lactam α-Position Improves 11-Deoxy-8-aza-PGE 1 Series EP 4 Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE 1 Analog (KMN-159) as a Potent EP 4 Agonist

Journal of medicinal chemistry, 2019-05, Vol.62 (9), p.4731-4741

2019

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Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (4), p.1051-1055

2013

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Binding thermodynamics of substituted diaminopyrimidine renin inhibitors

Analytical biochemistry, 2007, Vol.360 (1), p.30-40

2007

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Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (4), p.1046-1050

2013

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Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors

Bioorganic & medicinal chemistry, 2007-09, Vol.15 (17), p.5912-5949

2007

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2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3- b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (12), p.3349-3353

2007

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Optimization of a Pd-catalyzed intramolecular α-arylation synthesis of tricyclo-[7.3.1.0 2,7]-trideca-2,4,6-trien-13-ones

Tetrahedron letters, 2010-08, Vol.51 (33), p.4441-4444

2010

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Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide−Epoxide Cyclization

Organic letters, 2004-10, Vol.6 (22), p.4069-4072

2004

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The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (23), p.4235-4239

2003

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An Efficient Synthesis of Dihydroxyfluorenones via in Situ Pd(0)-Catalyzed Cross-Coupling

Synthesis (Stuttgart), 1998-08, Vol.1998 (8), p.1195-1198

Ciske, Fred L.

1998

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A Convenient Synthesis of Dengibsin

Journal of organic chemistry, 1996-05, Vol.61 (11), p.3920-3922

1996

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A simple method for coupling aldehydes to solid support

Bioorganic & medicinal chemistry letters, 1998-09, Vol.8 (17), p.2399-2402

1998

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The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones: Antibacterial agents: solutions for the evolving problems of resistance

Bioorganic & medicinal chemistry letters, 2003, Vol.13 (23), p.4235-4239

2003

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ChemInform Abstract: Optimization of a Pd-Catalyzed Intramolecular α-Arylation Synthesis of Tricyclo-[7.3.1.02.7]-trideca-2,4,6-trien-13-ones

ChemInform, 2010-11, Vol.41 (45), p.no-no

2010

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Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide-Epoxide Cyclization

ChemInform, 2005-02, Vol.36 (6), p.no-no

2005

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Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ

Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-[gamma]

Abstract 10067: A Nitric Oxide Donor Binds to SARS-CoV-2 Papain-Like Protease with Therapeutic Implications

Quantitative Measurement of JWH-018 and JWH-073 Metabolites Excreted in Human Urine

Novel nitric oxide donors are coronary vasodilators that also bind to the papain-like protease of SARS-CoV-2

Difluoromethylene at the γ‑Lactam α‑Position Improves 11-Deoxy-8-aza-PGE1 Series EP4 Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE1 Analog (KMN-159) as a Potent EP4 Agonist

Novel amide and imidazole compounds as potent hematopoietic prostaglandin D 2 synthase inhibitors

Novel amide and imidazole compounds as potent hematopoietic prostaglandin D2 synthase inhibitors

Difluoromethylene at the γ-Lactam α-Position Improves 11-Deoxy-8-aza-PGE 1 Series EP 4 Receptor Binding and Activity: 11-Deoxy-10,10-difluoro-8-aza-PGE 1 Analog (KMN-159) as a Potent EP 4 Agonist

Optimization of highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Binding thermodynamics of substituted diaminopyrimidine renin inhibitors

Highly selective 2,4-diaminopyrimidine-5-carboxamide inhibitors of Sky kinase

Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors

2-Aryl-2-hydroxyethylamine substituted 4-oxo-4,7-dihydrothieno[2,3- b]pyridines as broad-spectrum inhibitors of human herpesvirus polymerases

Optimization of a Pd-catalyzed intramolecular α-arylation synthesis of tricyclo-[7.3.1.0 2,7]-trideca-2,4,6-trien-13-ones

Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide−Epoxide Cyclization

The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones

An Efficient Synthesis of Dihydroxyfluorenones via in Situ Pd(0)-Catalyzed Cross-Coupling

A Convenient Synthesis of Dengibsin

A simple method for coupling aldehydes to solid support

The effect of remote chirality on the antibacterial activity of indolinyl, tetrahydroquinolyl and dihydrobenzoxazinyl oxazolidinones: Antibacterial agents: solutions for the evolving problems of resistance

ChemInform Abstract: Optimization of a Pd-Catalyzed Intramolecular α-Arylation Synthesis of Tricyclo-[7.3.1.02.7]-trideca-2,4,6-trien-13-ones

Practical Synthesis of 1-Aryl-6-(hydroxymethyl)-2-ketopiperazines via a 6-exo Amide-Epoxide Cyclization

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