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Inducible nitric oxide synthase: Regulation, structure, and inhibition

Medicinal research reviews, 2020-01, Vol.40 (1), p.158-189

2020

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Alkaloids of the Genus Datura : Review of a Rich Resource for Natural Product Discovery

Molecules (Basel, Switzerland), 2021-04, Vol.26 (9), p.2629

2021

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Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain

Chemical Society reviews, 2014-10, Vol.43 (19), p.6814-6838

2014

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Visible Light Mediated Activation and O-Glycosylation of Thioglycosides

Organic letters, 2013-01, Vol.15 (1), p.30-33

2013

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Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (15), p.8431-8436

2020

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Inhibition of interferon-gamma-stimulated melanoma progression by targeting neuronal nitric oxide synthase (nNOS)

Scientific reports, 2022-02, Vol.12 (1), p.1701-1701, Article 1701

2022

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Enzymatic synthesis and chemical inversion provide both enantiomers of bioactive epoxydocosapentaenoic acids

Journal of lipid research, 2018-11, Vol.59 (11), p.2237-2252

2018

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Topoisomerase 1B poisons: Over a half‐century of drug leads, clinical candidates, and serendipitous discoveries

Medicinal research reviews, 2019-07, Vol.39 (4), p.1294-1337

Cinelli, Maris A.

2019

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Hydrophilic, Potent, and Selective 7‑Substituted 2‑Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.7146-7165

2017

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Structures of human constitutive nitric oxide synthases

Acta crystallographica. Section D, Biological crystallography., 2014-10, Vol.70 (10), p.2667-2674

2014

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A Small Peptide Increases Drug Delivery in Human Melanoma Cells

Pharmaceutics, 2022-05, Vol.14 (5), p.1036

2022

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Alcohol-, Diol-, and Carbohydrate-Substituted Indenoisoquinolines as Topoisomerase I Inhibitors: Investigating the Relationships Involving Stereochemistry, Hydrogen Bonding, and Biological Activity

Journal of medicinal chemistry, 2011-07, Vol.54 (14), p.4937-4953

2011

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Asymmetric Total Synthesis of 19,20-Epoxydocosapentaenoic Acid, a Bioactive Metabolite of Docosahexaenoic Acid

Journal of organic chemistry, 2019-12, Vol.84 (23), p.15362-15372

2019

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Applications of Liquid Chromatography-Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study

Journal of visualized experiments, 2024-03 (205)

2024

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Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: Investigating the hypothesis of shared structure–activity relationships

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (20), p.7145-7155

2009

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Mass Spectrometry Does Not Need to Be a “Grind”: Plant Secondary Metabolites in Coffee and Black Pepper as a Practical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Teaching Tool

Journal of chemical education, 2024-03, Vol.101 (3), p.1257-1267

2024

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First Contact: 7‑Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate

Journal of medicinal chemistry, 2020-05, Vol.63 (9), p.4528-4554

2020

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Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors

Journal of medicinal chemistry, 2017-05, Vol.60 (9), p.3958-3978

2017

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Redirecting tropane alkaloid metabolism reveals pyrrolidine alkaloid diversity in Atropa belladonna

The New phytologist, 2023-03, Vol.237 (5), p.1810-1825

2023

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Activity of Aromathecins against African Trypanosomes

Antimicrobial agents and chemotherapy, 2018-11, Vol.62 (11)

2018

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Correction to Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.1075-1075

2019

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Simplified 2‑Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1513-1530

2014

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Phenyl Ether- and Aniline-Containing 2‑Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase

Journal of medicinal chemistry, 2015-11, Vol.58 (21), p.8694-8712

2015

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Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors

Biochemistry (Easton), 2016-10, Vol.55 (39), p.5587-5594

2016

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Identification, Synthesis, and Biological Evaluation of Metabolites of the Experimental Cancer Treatment Drugs Indotecan (LMP400) and Indimitecan (LMP776) and Investigation of Isomerically Hydroxylated Indenoisoquinoline Analogues as Topoisomerase I Poisons

Journal of medicinal chemistry, 2012-12, Vol.55 (24), p.10844-10862

2012

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Inducible nitric oxide synthase: Regulation, structure, and inhibition

Alkaloids of the Genus Datura : Review of a Rich Resource for Natural Product Discovery

Development of nitric oxide synthase inhibitors for neurodegeneration and neuropathic pain

Visible Light Mediated Activation and O-Glycosylation of Thioglycosides

Soluble epoxide hydrolase is an endogenous regulator of obesity-induced intestinal barrier dysfunction and bacterial translocation

Inhibition of interferon-gamma-stimulated melanoma progression by targeting neuronal nitric oxide synthase (nNOS)

Enzymatic synthesis and chemical inversion provide both enantiomers of bioactive epoxydocosapentaenoic acids

Topoisomerase 1B poisons: Over a half‐century of drug leads, clinical candidates, and serendipitous discoveries

Hydrophilic, Potent, and Selective 7‑Substituted 2‑Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors

Structures of human constitutive nitric oxide synthases

A Small Peptide Increases Drug Delivery in Human Melanoma Cells

Alcohol-, Diol-, and Carbohydrate-Substituted Indenoisoquinolines as Topoisomerase I Inhibitors: Investigating the Relationships Involving Stereochemistry, Hydrogen Bonding, and Biological Activity

Asymmetric Total Synthesis of 19,20-Epoxydocosapentaenoic Acid, a Bioactive Metabolite of Docosahexaenoic Acid

Applications of Liquid Chromatography-Tandem Mass Spectrometry in Natural Products Research: Tropane Alkaloids as a Case Study

Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: Investigating the hypothesis of shared structure–activity relationships

Mass Spectrometry Does Not Need to Be a “Grind”: Plant Secondary Metabolites in Coffee and Black Pepper as a Practical Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) Teaching Tool

First Contact: 7‑Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate

Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors

Redirecting tropane alkaloid metabolism reveals pyrrolidine alkaloid diversity in Atropa belladonna

Activity of Aromathecins against African Trypanosomes

Correction to Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors

Simplified 2‑Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition

Phenyl Ether- and Aniline-Containing 2‑Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase

Targeting Bacterial Nitric Oxide Synthase with Aminoquinoline-Based Inhibitors

Identification, Synthesis, and Biological Evaluation of Metabolites of the Experimental Cancer Treatment Drugs Indotecan (LMP400) and Indimitecan (LMP776) and Investigation of Isomerically Hydroxylated Indenoisoquinoline Analogues as Topoisomerase I Poisons

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