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Functional roles of alternative splicing factors in human disease

Wiley interdisciplinary reviews. RNA, 2015-05, Vol.6 (3), p.311-326

2015

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The Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina

PLoS genetics, 2016-08, Vol.12 (8), p.e1006256-e1006256

2016

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Epithelial―Mesenchymal Transition and Tumor Suppression Are Controlled by a Reciprocal Feedback Loop between ZEB1 and Grainyhead-like-2

Cancer research (Chicago, Ill.), 2013-10, Vol.73 (20), p.6299-6309

2013

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The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development

eLife, 2015-09, Vol.4

2015

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Suppression of the Epithelial-Mesenchymal Transition by Grainyhead-like-2

Cancer research (Chicago, Ill.), 2012-05, Vol.72 (9), p.2440-2453

2012

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CD44S-hyaluronan interactions protect cells resulting from EMT against anoikis

Matrix biology, 2015-10, Vol.48, p.55-65

2015

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Beta-Catenin Activation Promotes Liver Regeneration after Acetaminophen-Induced Injury

The American journal of pathology, 2009-09, Vol.175 (3), p.1056-1065

2009

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A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition

Molecular and Cellular Biology, 2011-10, Vol.31 (19), p.4036-4051

2011

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Multiphasic and Dynamic Changes in Alternative Splicing during Induction of Pluripotency Are Coordinated by Numerous RNA-Binding Proteins

Cell reports (Cambridge), 2016-04, Vol.15 (2), p.247-255

2016

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The RNA binding protein RBM38 (RNPC1) regulates splicing during late erythroid differentiation

PloS one, 2013-10, Vol.8 (10), p.e78031-e78031

2013

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siRNA-Mediated β-Catenin Knockdown in Human Hepatoma Cells Results in Decreased Growth and Survival

Neoplasia (New York, N.Y.), 2007-11, Vol.9 (11), p.951-959

2007

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Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis

Journal of cell science, 2013-01, Vol.126 (Pt 1), p.21-29

2013

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Genome-wide activities of RNA binding proteins that regulate cellular changes in the epithelial to mesenchymal transition (EMT)

Advances in experimental medicine and biology, 2014, Vol.825, p.267

2014

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Conditional Deletion of β-Catenin Reveals Its Role in Liver Growth and Regeneration

Gastroenterology (New York, N.Y. 1943), 2006-11, Vol.131 (5), p.1561-1572

2006

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ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development

Developmental cell, 2017-11, Vol.43 (3), p.318-331.e5

2017

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Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity

Cell reports (Cambridge), 2018-11, Vol.25 (9), p.2417-2430.e5

2018

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Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing

Arteriosclerosis, thrombosis, and vascular biology, 2016-07, Vol.36 (7), p.1434-1447

2016

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Unique phenotype of hepatocellular cancers with exon‐3 mutations in beta‐catenin gene

Hepatology (Baltimore, Md.), 2009-03, Vol.49 (3), p.821-831

2009

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Wnt/β‐catenin signaling mediates oval cell response in rodents

Hepatology (Baltimore, Md.), 2008-01, Vol.47 (1), p.288-295

2008

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Abstract A15: A reciprocal feedback loop between grainyhead-like-2 and ZEB1 controls EMT and tumor suppression

Cancer research (Chicago, Ill.), 2013-10, Vol.73 (19_Supplement), p.A15-A15

2013

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β‐Catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development

Hepatology (Baltimore, Md.), 2008-05, Vol.47 (5), p.1667-1679

2008

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Liver-Specific β-Catenin Knockout Mice Exhibit Defective Bile Acid and Cholesterol Homeostasis and Increased Susceptibility to Diet-Induced Steatohepatitis

The American journal of pathology, 2010-02, Vol.176 (2), p.744-753

2010

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Ablation of the epithelial‐specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number

Developmental dynamics, 2016-10, Vol.245 (10), p.991-1000

2016

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Abstract 157: Alternative Splicing of PLD1 and Its Role in Modulating Inflammatory Phenotypes in Primary Human Macrophages

Arteriosclerosis, thrombosis, and vascular biology, 2016-05, Vol.36 (suppl_1)

2016

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β-Catenin Regulates Vitamin C Biosynthesis and Cell Survival in Murine Liver

The Journal of biological chemistry, 2009-10, Vol.284 (41), p.28115-28127

2009

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Functional roles of alternative splicing factors in human disease

The Musashi 1 Controls the Splicing of Photoreceptor-Specific Exons in the Vertebrate Retina

Epithelial―Mesenchymal Transition and Tumor Suppression Are Controlled by a Reciprocal Feedback Loop between ZEB1 and Grainyhead-like-2

The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development

Suppression of the Epithelial-Mesenchymal Transition by Grainyhead-like-2

CD44S-hyaluronan interactions protect cells resulting from EMT against anoikis

Beta-Catenin Activation Promotes Liver Regeneration after Acetaminophen-Induced Injury

A Pathway for the Control of Anoikis Sensitivity by E-Cadherin and Epithelial-to-Mesenchymal Transition

Multiphasic and Dynamic Changes in Alternative Splicing during Induction of Pluripotency Are Coordinated by Numerous RNA-Binding Proteins

The RNA binding protein RBM38 (RNPC1) regulates splicing during late erythroid differentiation

siRNA-Mediated β-Catenin Knockdown in Human Hepatoma Cells Results in Decreased Growth and Survival

Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis

Genome-wide activities of RNA binding proteins that regulate cellular changes in the epithelial to mesenchymal transition (EMT)

Conditional Deletion of β-Catenin Reveals Its Role in Liver Growth and Regeneration

ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development

Esrp1-Regulated Splicing of Arhgef11 Isoforms Is Required for Epithelial Tight Junction Integrity

Transcriptome-Wide Analysis Reveals Modulation of Human Macrophage Inflammatory Phenotype Through Alternative Splicing

Unique phenotype of hepatocellular cancers with exon‐3 mutations in beta‐catenin gene

Wnt/β‐catenin signaling mediates oval cell response in rodents

Abstract A15: A reciprocal feedback loop between grainyhead-like-2 and ZEB1 controls EMT and tumor suppression

β‐Catenin deletion in hepatoblasts disrupts hepatic morphogenesis and survival during mouse development

Liver-Specific β-Catenin Knockout Mice Exhibit Defective Bile Acid and Cholesterol Homeostasis and Increased Susceptibility to Diet-Induced Steatohepatitis

Ablation of the epithelial‐specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number

Abstract 157: Alternative Splicing of PLD1 and Its Role in Modulating Inflammatory Phenotypes in Primary Human Macrophages

β-Catenin Regulates Vitamin C Biosynthesis and Cell Survival in Murine Liver

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