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Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

Best practice & research. Clinical haematology, 2017-12, Vol.30 (4), p.341-355

Ciechanover, Aaron

2017

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The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy

Trends in biochemical sciences (Amsterdam. Regular ed.), 2017-11, Vol.42 (11), p.873-886

2017

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Intracellular protein degradation: From a vague idea through the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting

Bioorganic & medicinal chemistry, 2013-06, Vol.21 (12), p.3400-3410

Ciechanover, Aaron

2013

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Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting

Biochimica et biophysica acta, 2012-01, Vol.1824 (1), p.3-13

Ciechanover, Aaron

2012

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Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

Experimental & molecular medicine, 2015-03, Vol.47 (3), p.e147-e147

2015

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Proteolysis: from the lysosome to ubiquitin and the proteasome

Nature reviews. Molecular cell biology, 2005-01, Vol.6 (1), p.79-87

Ciechanover, Aaron

2005

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Protein Quality Control by Molecular Chaperones in Neurodegeneration

Frontiers in neuroscience, 2017-04, Vol.11, p.185-185

2017

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The life cycle of the 26S proteasome： from birth, through regulation and function, and onto its death

Cell research, 2016-08, Vol.26 (8), p.869-885

2016

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Non-canonical ubiquitin-based signals for proteasomal degradation

Journal of cell science, 2012-02, Vol.125 (Pt 3), p.539-548

2012

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The 26 S Proteasome: From Basic Mechanisms to Drug Targeting

The Journal of biological chemistry, 2009-12, Vol.284 (49), p.33713-33718

2009

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Targeting Proteins for Destruction by the Ubiquitin System : Implications for Human Pathobiology

Annual review of pharmacology and toxicology, 2009-01, Vol.49 (1), p.73-96

2009

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The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation

Nature reviews. Molecular cell biology, 2011-09, Vol.12 (9), p.605

2011

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p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome

Proceedings of the National Academy of Sciences - PNAS, 2016-11, Vol.113 (47), p.E7490-E7499

2016

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The unravelling of the ubiquitin system

Nature reviews. Molecular cell biology, 2015-05, Vol.16 (5), p.322

Ciechanover, Aaron

2015

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Intracellular Protein Degradation: From a Vague Idea, through the Lysosome and the Ubiquitin-Proteasome System, and onto Human Diseases and Drug Targeting (Nobel Lecture)

Angewandte Chemie (International ed.), 2005-09, Vol.44 (37), p.5944-5967

Ciechanover, Aaron

2005

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The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

Cancer cell, 2008-07, Vol.14 (1), p.10-21

2008

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Intracellular Protein Degradation: From a Vague Idea Thru the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting

Experimental biology and medicine (Maywood, N.J.), 2006-07, Vol.231 (7), p.1197-1211

Ciechanover, Aaron

2006

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The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction

Physiological reviews, 2002-04, Vol.82 (2), p.373-428

2002

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p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis

Nature communications, 2017-07, Vol.8 (1), p.102-102, Article 102

2017

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Degradation of ubiquitin: The fate of the cellular reaper

Cell cycle (Georgetown, Tex.), 2010-02, Vol.9 (3), p.523-530

2010

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THE UBIQUITIN SYSTEM

Annual review of biochemistry, 1998-01, Vol.67 (1), p.425-479

1998

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Post-translational modification profiling – A novel tool for mapping the protein modification landscape in cancer

Experimental biology and medicine (Maywood, N.J.), 2016-08, Vol.241 (14), p.1475-1482

2016

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Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

Nature cell biology, 2015-07, Vol.17 (7), p.917

2015

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Monoubiquitination joins polyubiquitination as an esteemed proteasomal targeting signal

BioEssays, 2017-06, Vol.39 (6), p.n/a

2017

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The Polycomb Protein Ring1B Generates Self Atypical Mixed Ubiquitin Chains Required for Its In Vitro Histone H2A Ligase Activity

Molecular cell, 2006-12, Vol.24 (5), p.701-711

2006

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Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy

Intracellular protein degradation: From a vague idea through the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting

Intracellular protein degradation: From a vague idea thru the lysosome and the ubiquitin–proteasome system and onto human diseases and drug targeting

Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

Proteolysis: from the lysosome to ubiquitin and the proteasome

Protein Quality Control by Molecular Chaperones in Neurodegeneration

The life cycle of the 26S proteasome： from birth, through regulation and function, and onto its death

Non-canonical ubiquitin-based signals for proteasomal degradation

The 26 S Proteasome: From Basic Mechanisms to Drug Targeting

Targeting Proteins for Destruction by the Ubiquitin System : Implications for Human Pathobiology

The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation

p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome

The unravelling of the ubiquitin system

Intracellular Protein Degradation: From a Vague Idea, through the Lysosome and the Ubiquitin-Proteasome System, and onto Human Diseases and Drug Targeting (Nobel Lecture)

The HECT Family of E3 Ubiquitin Ligases: Multiple Players in Cancer Development

Intracellular Protein Degradation: From a Vague Idea Thru the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting

The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction

p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis

Degradation of ubiquitin: The fate of the cellular reaper

THE UBIQUITIN SYSTEM

Post-translational modification profiling – A novel tool for mapping the protein modification landscape in cancer

Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding

Monoubiquitination joins polyubiquitination as an esteemed proteasomal targeting signal

The Polycomb Protein Ring1B Generates Self Atypical Mixed Ubiquitin Chains Required for Its In Vitro Histone H2A Ligase Activity

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