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KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

Nature (London), 2009-09, Vol.461 (7262), p.415-418

2009

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Lysine-79 of Histone H3 Is Hypomethylated at Silenced Loci in Yeast and Mammalian Cells: A Potential Mechanism for Position-Effect Variegation

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (4), p.1820-1825

2003

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Increased Ionizing Radiation Sensitivity and Genomic Instability in the Absence of Histone H2AX

Proceedings of the National Academy of Sciences - PNAS, 2002-06, Vol.99 (12), p.8173-8178

2002

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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

Nature, 2007-12, Vol.450 (7172), p.1106-1110

2007

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The murine IgH locus contains a distinct DNA sequence motif for the chromatin regulatory factor CTCF

The Journal of biological chemistry, 2019-09, Vol.294 (37), p.13580-13592

2019

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ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

Nature (London), 2000-05, Vol.405 (6785), p.477-482

2000

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Antigen Receptor Loci Poised for V(D)J Rearrangement Are Broadly Associated with BRG1 and Flanked by Peaks of Histone H3 Dimethylated at Lysine 4

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (20), p.11577-11582

2003

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Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses

Frontiers in immunology, 2022-08, Vol.13, p.987298-987298

2022

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1340 NDI-101150 is a potent and highly selective hematopoietic progenitor kinase 1 (HPK1) inhibitor that promotes a robust and broad anti-tumor immune response

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A1494-A1494

2023

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Histone lysine methylation in genomic imprinting

Epigenetics, 2009-05, Vol.4 (4), p.216-220

2009

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Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations

Molecular immunology, 2012-08, Vol.52 (1), p.1-8

2012

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460 Discovery of potent Cbl-b inhibitors demonstrating enhanced immune cell activity and tumor growth inhibition in murine syngeneic models

Journal for immunotherapy of cancer, 2022, Vol.10 (Suppl 2), p.A480-A480

2022

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685 A highly selective and potent HPK1 inhibitor enhances immune cell activation and induces robust tumor growth inhibition in a murine syngeneic tumor model

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A724-A724

2020

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Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Science (American Association for the Advancement of Science), 2016-03, Vol.351 (6278), p.1208-1213

2016

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Abstract 1649: Mechanistic understanding of HPK1 inhibition on enhanced human T cell activation and tumor immunity in a syngeneic model

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1649-1649

2021

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Chromatin Immunoprecipitation in the Analysis of Large Chromatin Domains Across Murine Antigen Receptor Loci

Methods in Enzymology, 2003, Vol.376, p.334-348

2003

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Abstract 942: HPK1, hematopoietic progenitor kinase 1, is a promising therapeutic target for cancer immunotherapy

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.942-942

2020

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Abstract 589: Discovery of NTX-001, a potent Cbl-b inhibitor with antitumor activity in syngeneic models

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.589-589

2022

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Mice lacking SI14 tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations

Molecular immunology, 2012-08, Vol.52 (1), p.1-8

2012

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Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

Current biology, 2001-06, Vol.11 (12), p.962-966

2001

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Chromatin immunoprecipitation in the analysis of large chromatin domains across murine antigen receptor loci

Methods in enzymology, 2004, Vol.376, p.334

2004

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Chromatin modifications as clues to the regulation of antigen receptor assembly

Novartis Foundation symposium, 2004, Vol.259, p.146

2004

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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V

Nature (London), 2007-12, Vol.450 (7172), p.1106

2007

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RAG2 PHD finger couples histone H3 lysine 4 trimethylation with VJ recombination

Nature (London), 2007-12, Vol.450 (7172), p.1106

2007

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The epigenetic regulation of V(D)J recombination: Chromatin architecture and the insulator protein, CTCF

Ciccone, David Nicholas

2007

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KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints

Lysine-79 of Histone H3 Is Hypomethylated at Silenced Loci in Yeast and Mammalian Cells: A Potential Mechanism for Position-Effect Variegation

Increased Ionizing Radiation Sensitivity and Genomic Instability in the Absence of Histone H2AX

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination

The murine IgH locus contains a distinct DNA sequence motif for the chromatin regulatory factor CTCF

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

Antigen Receptor Loci Poised for V(D)J Rearrangement Are Broadly Associated with BRG1 and Flanked by Peaks of Histone H3 Dimethylated at Lysine 4

Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses

1340 NDI-101150 is a potent and highly selective hematopoietic progenitor kinase 1 (HPK1) inhibitor that promotes a robust and broad anti-tumor immune response

Histone lysine methylation in genomic imprinting

Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations

460 Discovery of potent Cbl-b inhibitors demonstrating enhanced immune cell activity and tumor growth inhibition in murine syngeneic models

685 A highly selective and potent HPK1 inhibitor enhances immune cell activation and induces robust tumor growth inhibition in a murine syngeneic tumor model

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Abstract 1649: Mechanistic understanding of HPK1 inhibition on enhanced human T cell activation and tumor immunity in a syngeneic model

Chromatin Immunoprecipitation in the Analysis of Large Chromatin Domains Across Murine Antigen Receptor Loci

Abstract 942: HPK1, hematopoietic progenitor kinase 1, is a promising therapeutic target for cancer immunotherapy

Abstract 589: Discovery of NTX-001, a potent Cbl-b inhibitor with antitumor activity in syngeneic models

Mice lacking SI14 tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

Chromatin immunoprecipitation in the analysis of large chromatin domains across murine antigen receptor loci

Chromatin modifications as clues to the regulation of antigen receptor assembly

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with VJ recombination

The epigenetic regulation of V(D)J recombination: Chromatin architecture and the insulator protein, CTCF

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