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HPMA Copolymer-Based Nanomedicines in Controlled Drug Delivery

Journal of personalized medicine, 2021-02, Vol.11 (2), p.115

2021

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Fluorescence Imaging as a Tool in Preclinical Evaluation of Polymer-Based Nano-DDS Systems Intended for Cancer Treatment

Pharmaceutics, 2019-09, Vol.11 (9), p.471

2019

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A tumor-targeted polymer theranostics platform for positron emission tomography and fluorescence imaging

Nanoscale, 2017-08, Vol.9 (30), p.10906-10918

2017

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Superior Penetration and Cytotoxicity of HPMA Copolymer Conjugates of Pirarubicin in Tumor Cell Spheroid

Molecular pharmaceutics, 2019-08, Vol.16 (8), p.3452-3459

2019

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Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice

European journal of pharmaceutics and biopharmaceutics, 2015-02, Vol.90, p.90-96

2015

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Intratumoral Distribution and pH-Dependent Drug Release of High Molecular Weight HPMA Copolymer Drug Conjugates Strongly Depend on Specific Tumor Substructure and Microenvironment

International journal of molecular sciences, 2020-08, Vol.21 (17), p.6029

2020

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Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate

European journal of pharmaceutical sciences, 2017-08, Vol.106, p.10-19

2017

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Binding of HSA to Macromolecular pHPMA Based Nanoparticles for Drug Delivery: An Investigation Using Fluorescence Methods

Langmuir, 2018-07, Vol.34 (27), p.7998-8006

2018

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Hydrolytically Degradable Polymer Micelles for Drug Delivery: A SAXS/SANS Kinetic Study

Biomacromolecules, 2013-11, Vol.14 (11), p.4061-4070

2013

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Cross-Linking Effects Dictate the Preference of Galectins to Bind LacNAc-Decorated HPMA Copolymers

International journal of molecular sciences, 2021-06, Vol.22 (11), p.6000

2021

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HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicines for Oncotherapy

Pharmaceutics, 2021-01, Vol.13 (2), p.179

2021

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Molecular Mechanisms of the Interactions of N -(2-Hydroxypropyl)methacrylamide Copolymers Designed for Cancer Therapy with Blood Plasma Proteins

Pharmaceutics, 2020-01, Vol.12 (2), p.106

2020

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HPMA Copolymer–Drug Conjugates with Controlled Tumor‐Specific Drug Release

Macromolecular bioscience, 2018-01, Vol.18 (1), p.n/a

2018

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Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage

Journal of controlled release, 2014-01, Vol.174, p.81-87

2014

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Fluorescence optical imaging in anticancer drug delivery

Journal of controlled release, 2016-03, Vol.226, p.168-181

2016

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Polymer‐Based Drug‐Free Therapeutics for Anticancer, Anti‐Inflammatory, and Antibacterial Treatment

Macromolecular bioscience, 2021-08, Vol.21 (8), p.e2100135-n/a

2021

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Biodegradable star HPMA polymer–drug conjugates: Biodegradability, distribution and anti-tumor efficacy

Journal of controlled release, 2011-09, Vol.154 (3), p.241-248

2011

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Long circulating liposomal platform utilizing hydrophilic polymer-based surface modification: preparation, characterisation, and biological evaluation

International journal of pharmaceutics, 2024-08, Vol.661, p.124465, Article 124465

2024

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HPMA copolymer conjugate with pirarubicin: In vitro and ex vivo stability and drug release study

International journal of pharmaceutics, 2018-01, Vol.536 (1), p.108-115

2018

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Polymer‐Based Drug‐Free Therapeutics for Anticancer, Anti‐Inflammatory, and Antibacterial Treatment

Macromolecular bioscience, 2021-08, Vol.21 (8), p.n/a

2021

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Highly effective anti-tumor nanomedicines based on HPMA copolymer conjugates with pirarubicin prepared by controlled RAFT polymerization

Acta biomaterialia, 2020-04, Vol.106, p.256-266

2020

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Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties

Journal of controlled release, 2020-05, Vol.321, p.718-733

2020

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N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation

European journal of pharmaceutical sciences, 2010-11, Vol.41 (3), p.473-482

2010

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Interaction of spin-labeled HPMA-based nanoparticles with human blood plasma proteins - the introduction of protein-corona-free polymer nanomedicine

Nanoscale, 2018-04, Vol.10 (13), p.6194-6204

2018

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Happy Birthday Karel

Macromolecular bioscience, 2018-01, Vol.18 (1), p.n/a

2018

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HPMA Copolymer-Based Nanomedicines in Controlled Drug Delivery

Fluorescence Imaging as a Tool in Preclinical Evaluation of Polymer-Based Nano-DDS Systems Intended for Cancer Treatment

A tumor-targeted polymer theranostics platform for positron emission tomography and fluorescence imaging

Superior Penetration and Cytotoxicity of HPMA Copolymer Conjugates of Pirarubicin in Tumor Cell Spheroid

Comparison between linear and star-like HPMA conjugated pirarubicin (THP) in pharmacokinetics and antitumor activity in tumor bearing mice

Intratumoral Distribution and pH-Dependent Drug Release of High Molecular Weight HPMA Copolymer Drug Conjugates Strongly Depend on Specific Tumor Substructure and Microenvironment

Comparison of the pharmacological and biological properties of HPMA copolymer-pirarubicin conjugates: A single-chain copolymer conjugate and its biodegradable tandem-diblock copolymer conjugate

Binding of HSA to Macromolecular pHPMA Based Nanoparticles for Drug Delivery: An Investigation Using Fluorescence Methods

Hydrolytically Degradable Polymer Micelles for Drug Delivery: A SAXS/SANS Kinetic Study

Cross-Linking Effects Dictate the Preference of Galectins to Bind LacNAc-Decorated HPMA Copolymers

HPMA-Based Copolymers Carrying STAT3 Inhibitor Cucurbitacin-D as Stimulus-Sensitive Nanomedicines for Oncotherapy

Molecular Mechanisms of the Interactions of N -(2-Hydroxypropyl)methacrylamide Copolymers Designed for Cancer Therapy with Blood Plasma Proteins

HPMA Copolymer–Drug Conjugates with Controlled Tumor‐Specific Drug Release

Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl)methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage

Fluorescence optical imaging in anticancer drug delivery

Polymer‐Based Drug‐Free Therapeutics for Anticancer, Anti‐Inflammatory, and Antibacterial Treatment

Biodegradable star HPMA polymer–drug conjugates: Biodegradability, distribution and anti-tumor efficacy

Long circulating liposomal platform utilizing hydrophilic polymer-based surface modification: preparation, characterisation, and biological evaluation

HPMA copolymer conjugate with pirarubicin: In vitro and ex vivo stability and drug release study

Polymer‐Based Drug‐Free Therapeutics for Anticancer, Anti‐Inflammatory, and Antibacterial Treatment

Highly effective anti-tumor nanomedicines based on HPMA copolymer conjugates with pirarubicin prepared by controlled RAFT polymerization

Polymer nanomedicines based on micelle-forming amphiphilic or water-soluble polymer-doxorubicin conjugates: Comparative study of in vitro and in vivo properties related to the polymer carrier structure, composition, and hydrodynamic properties

N-(2-Hydroxypropyl)methacrylamide-based polymer conjugates with pH-controlled activation of doxorubicin for cell-specific or passive tumour targeting. Synthesis by RAFT polymerisation and physicochemical characterisation

Interaction of spin-labeled HPMA-based nanoparticles with human blood plasma proteins - the introduction of protein-corona-free polymer nanomedicine

Happy Birthday Karel

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