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Aldose Reductase Deficiency Prevents Diabetes-Induced Blood-Retinal Barrier Breakdown, Apoptosis, and Glial Reactivation in the Retina of db/db Mice

Diabetes (New York, N.Y.), 2005-11, Vol.54 (11), p.3119-3125

2005

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Endothelial endothelin-1 over-expression using receptor tyrosine kinase tie-1 promoter leads to more severe vascular permeability and blood brain barrier breakdown after transient middle cerebral artery occlusion

Brain research, 2009-04, Vol.1266, p.121-129

2009

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Regulation of Nucleocytoplasmic Trafficking of Transcription Factor OREBP/TonEBP/NFAT5

The Journal of biological chemistry, 2006-08, Vol.281 (33), p.23870-23879

2006

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Phosphorylation by Casein Kinase 1 Regulates Tonicity-induced Osmotic Response Element-binding Protein/Tonicity Enhancer-binding Protein Nucleocytoplasmic Trafficking

The Journal of biological chemistry, 2008-06, Vol.283 (25), p.17624-17634

2008

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Tonicity-responsive microRNAs contribute to the maximal induction of osmoregulatory transcription factor OREBP in response to high-NaCl hypertonicity

Nucleic acids research, 2011-01, Vol.39 (2), p.475

2011

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Aldose Reductase–Deficient Mice Are Protected From Delayed Motor Nerve Conduction Velocity, Increased c-Jun NH2-Terminal Kinase Activation, Depletion of Reduced Glutathione, Increased Superoxide Accumulation, and DNA Damage

Diabetes (New York, N.Y.), 2006-07, Vol.55 (7), p.1946-1953

2006

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Pseudolaric Acid B, a Novel Microtubule-Destabilizing Agent That Circumvents Multidrug Resistance Phenotype and Exhibits Antitumor Activity In vivo

Clinical cancer research, 2005-08, Vol.11 (16), p.6002-6011

2005

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Fyn and p38 Signaling Are Both Required for Maximal Hypertonic Activation of the Osmotic Response Element-binding Protein/Tonicity-responsive Enhancer-binding Protein (OREBP/TonEBP)

The Journal of biological chemistry, 2002-11, Vol.277 (48), p.46085-46092

2002

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Ion Channels in Mesenchymal Stem Cells from Rat Bone Marrow

Stem cells (Dayton, Ohio), 2006-06, Vol.24 (6), p.1519-1528

2006

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Identification and Characterization of a Novel Human Aldose Reductase-like Gene

The Journal of biological chemistry, 1998-05, Vol.273 (19), p.11429-11435

1998

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Aldose Reductase Regulates Hepatic Peroxisome Proliferator-activated Receptor α Phosphorylation and Activity to Impact Lipid Homeostasis

The Journal of biological chemistry, 2008-06, Vol.283 (25), p.17175-17183

2008

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Noninvasive Monitoring of Diabetes-Induced Cutaneous Nerve Fiber Loss and Hypoalgesia in thy1-YFP Transgenic Mice

Diabetes (New York, N.Y.), 2005-11, Vol.54 (11), p.3112-3118

2005

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Transgenic mice overexpressing aldose reductase in Schwann cells show more severe nerve conduction velocity deficit and oxidative stress under hyperglycemic stress

Molecular and cellular neuroscience, 2003-08, Vol.23 (4), p.638-647

2003

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Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury

Experimental eye research, 2007-11, Vol.85 (5), p.608-616

2007

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Identification and Characterization of Multiple Osmotic Response Sequences in the Human Aldose Reductase Gene

The Journal of biological chemistry, 1997-06, Vol.272 (26), p.16431-16437

1997

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Purification, Identification, and Characterization of an Osmotic Response Element Binding Protein

Biochemical and biophysical research communications, 2000-04, Vol.270 (1), p.52-61

2000

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Diabetic cataracts: mechanisms and management

Diabetes/metabolism research and reviews, 2010-03, Vol.26 (3), p.172-180

2010

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Aldose reductase deficiency leads to oxidative stress-induced dopaminergic neuronal loss and autophagic abnormality in an animal model of Parkinson’s disease

Neurobiology of aging, 2017-02, Vol.50, p.119-133

2017

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内皮细胞高表达人清道夫受体A的转基因小鼠的建立

中华医学杂志(英文版), 2001, Vol.114 (10), p.1078-1083

2001

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Exchange protein activated by cAMP 1 (Epac1)‐deficient mice develop β‐cell dysfunction and metabolic syndrome

The FASEB journal, 2013-10, Vol.27 (10), p.4122-4135

2013

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Effects of sorbitol dehydrogenase deficiency on nerve conduction in experimental diabetic mice

Diabetes (New York, N.Y.), 1998-06, Vol.47 (6), p.961

1998

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Interaction between the polyol pathway and non-enzymatic glycation on mesangial cell gene expression

Nephron, 2004-01, Vol.98 (3), p.e89-e99

2004

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Targeted over-expression of endothelin-1 in astrocytes leads to more severe brain damage and vasospasm after subarachnoid hemorrhage

BMC neuroscience, 2013-10, Vol.14 (1), p.131-131, Article 131

2013

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Contributions of polyol pathway to oxidative stress in diabetic cataract

The FASEB journal, 1999-01, Vol.13 (1), p.23-30

1999

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Endothelin-1 overexpression leads to further water accumulation and brain edema after middle cerebral artery occlusion via aquaporin 4 expression in astrocytic end-feet

Journal of Cerebral Blood Flow & Metabolism, 2005-08, Vol.25 (8), p.998-1011

2005

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Aldose Reductase Deficiency Prevents Diabetes-Induced Blood-Retinal Barrier Breakdown, Apoptosis, and Glial Reactivation in the Retina of db/db Mice

Endothelial endothelin-1 over-expression using receptor tyrosine kinase tie-1 promoter leads to more severe vascular permeability and blood brain barrier breakdown after transient middle cerebral artery occlusion

Regulation of Nucleocytoplasmic Trafficking of Transcription Factor OREBP/TonEBP/NFAT5

Phosphorylation by Casein Kinase 1 Regulates Tonicity-induced Osmotic Response Element-binding Protein/Tonicity Enhancer-binding Protein Nucleocytoplasmic Trafficking

Tonicity-responsive microRNAs contribute to the maximal induction of osmoregulatory transcription factor OREBP in response to high-NaCl hypertonicity

Aldose Reductase–Deficient Mice Are Protected From Delayed Motor Nerve Conduction Velocity, Increased c-Jun NH2-Terminal Kinase Activation, Depletion of Reduced Glutathione, Increased Superoxide Accumulation, and DNA Damage

Pseudolaric Acid B, a Novel Microtubule-Destabilizing Agent That Circumvents Multidrug Resistance Phenotype and Exhibits Antitumor Activity In vivo

Fyn and p38 Signaling Are Both Required for Maximal Hypertonic Activation of the Osmotic Response Element-binding Protein/Tonicity-responsive Enhancer-binding Protein (OREBP/TonEBP)

Ion Channels in Mesenchymal Stem Cells from Rat Bone Marrow

Identification and Characterization of a Novel Human Aldose Reductase-like Gene

Aldose Reductase Regulates Hepatic Peroxisome Proliferator-activated Receptor α Phosphorylation and Activity to Impact Lipid Homeostasis

Noninvasive Monitoring of Diabetes-Induced Cutaneous Nerve Fiber Loss and Hypoalgesia in thy1-YFP Transgenic Mice

Transgenic mice overexpressing aldose reductase in Schwann cells show more severe nerve conduction velocity deficit and oxidative stress under hyperglycemic stress

Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury

Identification and Characterization of Multiple Osmotic Response Sequences in the Human Aldose Reductase Gene

Purification, Identification, and Characterization of an Osmotic Response Element Binding Protein

Diabetic cataracts: mechanisms and management

Aldose reductase deficiency leads to oxidative stress-induced dopaminergic neuronal loss and autophagic abnormality in an animal model of Parkinson’s disease

内皮细胞高表达人清道夫受体A的转基因小鼠的建立

Exchange protein activated by cAMP 1 (Epac1)‐deficient mice develop β‐cell dysfunction and metabolic syndrome

Effects of sorbitol dehydrogenase deficiency on nerve conduction in experimental diabetic mice

Interaction between the polyol pathway and non-enzymatic glycation on mesangial cell gene expression

Targeted over-expression of endothelin-1 in astrocytes leads to more severe brain damage and vasospasm after subarachnoid hemorrhage

Contributions of polyol pathway to oxidative stress in diabetic cataract

Endothelin-1 overexpression leads to further water accumulation and brain edema after middle cerebral artery occlusion via aquaporin 4 expression in astrocytic end-feet

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