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Metronomic chemotherapy using orally active carboplatin/deoxycholate complex to maintain drug concentration within a tolerable range for effective cancer management

Journal of controlled release, 2017-03, Vol.249, p.42-52

2017

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Dual mechanistic TRAIL nanocarrier based on PEGylated heparin taurocholate and protamine which exerts both pro-apoptotic and anti-angiogenic effects

Journal of controlled release, 2021-08, Vol.336, p.181-191

2021

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Strategies for non-invasive delivery of biologics

Journal of drug targeting, 2012-07, Vol.20 (6), p.481-501

2012

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Oligomeric bile acid-mediated oral delivery of low molecular weight heparin

Journal of controlled release, 2014-02, Vol.175, p.17-24

2014

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Oral delivery of a potent anti-angiogenic heparin conjugate by chemical conjugation and physical complexation using deoxycholic acid

Biomaterials, 2014-08, Vol.35 (24), p.6543-6552

2014

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Paclitaxel loaded nano-aggregates based on pH sensitive polyaspartamide amphiphilic graft copolymers

International journal of pharmaceutics, 2012-03, Vol.424 (1-2), p.26-32

2012

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Nanofiber‐based glaucoma drainage implant improves surgical outcomes by modulating fibroblast behavior

Bioengineering & translational medicine, 2023-05, Vol.8 (3), p.e10487-n/a

2023

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Functionalized heparin-protamine based self-assembled nanocomplex for efficient anti-angiogenic therapy

Journal of controlled release, 2015-01, Vol.197, p.180-189

2015

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Anticoagulation therapy promotes the tumor immune-microenvironment and potentiates the efficacy of immunotherapy by alleviating hypoxia

Journal for immunotherapy of cancer, 2021-08, Vol.9 (8), p.e002332

2021

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Self‐Triggered Apoptosis Enzyme Prodrug Therapy (STAEPT): Enhancing Targeted Therapies via Recurrent Bystander Killing Effect by Exploiting Caspase‐Cleavable Linker

Advanced science, 2018-07, Vol.5 (7), p.1800368-n/a

2018

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Potentiation of anti-angiogenic activity of heparin by blocking the ATIII-interacting pentasaccharide unit and increasing net anionic charge

Biomaterials, 2012-12, Vol.33 (35), p.9070-9079

2012

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Polyproline‐type helical‐structured low‐molecular weight heparin (LMWH)‐taurocholate conjugate as a new angiogenesis inhibitor

International journal of cancer, 2009-06, Vol.124 (12), p.2755-2765

2009

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Cyclic RGDyk-conjugated LMWH-taurocholate derivative as a targeting angiogenesis inhibitor

Journal of controlled release, 2012-11, Vol.164 (1), p.8-16

2012

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Preliminary safety evaluation of a taurocholate-conjugated low-molecular-weight heparin derivative (LHT7): a potent angiogenesis inhibitor

Journal of applied toxicology, 2015-01, Vol.35 (1), p.104-115

2015

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Abstract 2676: Radiotherapy-assisted tumor selective metronomic oral chemotherapy

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2676-2676

2018

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Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3

Molecular biology of the cell, 2021-11, Vol.32 (21), p.ar21-ar21

2021

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Abstract 1222: Caspase mediated prodrugs RGDEVD-DOX with EMC-DEVD-S-DOX in combination with anti PD-1 antibody for triple negative breast cancer

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1222-1222

2019

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Highly potent monomethyl auristatin E prodrug activated by caspase-3 for the chemoradiotherapy of triple-negative breast cancer

Biomaterials, 2019-02, Vol.192, p.109-117

2019

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Abstract LB-A08: Novel strategy for treatment of triple-negative breast cancer by highly potent caspase-cleavable docetaxel prodrug

Molecular cancer therapeutics, 2019-12, Vol.18 (12_Supplement), p.LB-A08-LB-A08

2019

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Hypoxia-tropic Protein Nanocages for Modulation of Tumor- and Chemotherapy-Associated Hypoxia

ACS nano, 2019-01, Vol.13 (1), p.236-247

2019

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Caspase-3 mediated switch therapy of self-triggered and long-acting prodrugs for metastatic TNBC

Journal of controlled release, 2022-06, Vol.346, p.136-147

2022

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Metronomic dose-finding approach in oral chemotherapy by experimentally-driven integrative mathematical modeling

Biomaterials, 2022-07, Vol.286, p.121584-121584, Article 121584

2022

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Overcoming physical stromal barriers to cancer immunotherapy

Drug delivery and translational research, 2021-12, Vol.11 (6), p.2430-2447

2021

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Reduced graphene oxide nanosheets coated with an anti-angiogenic anticancer low-molecular-weight heparin derivative for delivery of anticancer drugs

Journal of controlled release, 2014-09, Vol.189, p.80-89

2014

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Stimulating macropinocytosis of peptide-drug conjugates through DNA-dependent protein kinase inhibition for treating KRAS-mutant cancer

Journal of controlled release, 2024-08, Vol.372, p.176-193

2024

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Metronomic chemotherapy using orally active carboplatin/deoxycholate complex to maintain drug concentration within a tolerable range for effective cancer management

Dual mechanistic TRAIL nanocarrier based on PEGylated heparin taurocholate and protamine which exerts both pro-apoptotic and anti-angiogenic effects

Strategies for non-invasive delivery of biologics

Oligomeric bile acid-mediated oral delivery of low molecular weight heparin

Oral delivery of a potent anti-angiogenic heparin conjugate by chemical conjugation and physical complexation using deoxycholic acid

Paclitaxel loaded nano-aggregates based on pH sensitive polyaspartamide amphiphilic graft copolymers

Nanofiber‐based glaucoma drainage implant improves surgical outcomes by modulating fibroblast behavior

Functionalized heparin-protamine based self-assembled nanocomplex for efficient anti-angiogenic therapy

Anticoagulation therapy promotes the tumor immune-microenvironment and potentiates the efficacy of immunotherapy by alleviating hypoxia

Self‐Triggered Apoptosis Enzyme Prodrug Therapy (STAEPT): Enhancing Targeted Therapies via Recurrent Bystander Killing Effect by Exploiting Caspase‐Cleavable Linker

Potentiation of anti-angiogenic activity of heparin by blocking the ATIII-interacting pentasaccharide unit and increasing net anionic charge

Polyproline‐type helical‐structured low‐molecular weight heparin (LMWH)‐taurocholate conjugate as a new angiogenesis inhibitor

Cyclic RGDyk-conjugated LMWH-taurocholate derivative as a targeting angiogenesis inhibitor

Preliminary safety evaluation of a taurocholate-conjugated low-molecular-weight heparin derivative (LHT7): a potent angiogenesis inhibitor

Abstract 2676: Radiotherapy-assisted tumor selective metronomic oral chemotherapy

Keratin 19 interacts with GSK3β to regulate its nuclear accumulation and degradation of cyclin D3

Abstract 1222: Caspase mediated prodrugs RGDEVD-DOX with EMC-DEVD-S-DOX in combination with anti PD-1 antibody for triple negative breast cancer

Highly potent monomethyl auristatin E prodrug activated by caspase-3 for the chemoradiotherapy of triple-negative breast cancer

Abstract LB-A08: Novel strategy for treatment of triple-negative breast cancer by highly potent caspase-cleavable docetaxel prodrug

Hypoxia-tropic Protein Nanocages for Modulation of Tumor- and Chemotherapy-Associated Hypoxia

Caspase-3 mediated switch therapy of self-triggered and long-acting prodrugs for metastatic TNBC

Metronomic dose-finding approach in oral chemotherapy by experimentally-driven integrative mathematical modeling

Overcoming physical stromal barriers to cancer immunotherapy

Reduced graphene oxide nanosheets coated with an anti-angiogenic anticancer low-molecular-weight heparin derivative for delivery of anticancer drugs

Stimulating macropinocytosis of peptide-drug conjugates through DNA-dependent protein kinase inhibition for treating KRAS-mutant cancer

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