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Intratumoral (IT) Injection of the TLR9 agonist tilsotolimod (IMO-2125) in combination with ipilimumab (ipi) triggers durable responses in PD-1 inhibitor refractory metastatic melanoma (rMM): Results from a multicenter, phase I/II study

Annals of oncology, 2018-10, Vol.29, p.viii442-viii442

2018

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A Facile One-Pot Expeditious Synthesis of Thiazolyl-pyrazolones

Phosphorus, sulfur, and silicon and the related elements, 2011-03, Vol.186 (3), p.489-495

2011

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Bivalent IAP antagonists, but not monovalent IAP antagonists, inhibit TNF-mediated NF- κ B signaling by degrading TRAF2-associated cIAP1 in cancer cells

Cell death discovery, 2017-01, Vol.3 (1), p.16046-16046, Article 16046

2017

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1543 Type 1 interferon signaling correlates with patient-reported itch in dermatomyositis

Journal of investigative dermatology, 2023-05, Vol.143 (5), p.S265-S265

2023

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Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase

Bioorganic & medicinal chemistry letters, 2006, Vol.16 (1), p.100-103

2006

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Evaluating the Efficacy of Transresveratrol in Extraction Socket of Impacted Mandibular Third Molar: A Double-blind Study

World Journal of Dentistry, 2023-11, Vol.14 (10), p.869-876

2023

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In vivo model of adeno-associated virus vector persistence and rescue

Journal of Virology, 1996-05, Vol.70 (5), p.3235-3241

1996

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IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

Cell, 2007-11, Vol.131 (4), p.682-693

2007

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LB1115 A double-blind, placebo-controlled, phase 2 trial of IMO-8400, a novel toll-like receptor 7/8/9 antagonist, in dermatomyositis

Journal of investigative dermatology, 2019-09, Vol.139 (9), p.B18-B18

2019

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Mechanism of Action of a Pestivirus Antiviral Compound

Proceedings of the National Academy of Sciences - PNAS, 2000-07, Vol.97 (14), p.7981-7986

2000

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1083MO Final results from ILLUMINATE-204, a phase I/II trial of intratumoral tilsotolimod in combination with ipilimumab in PD-1 inhibitor refractory advanced melanoma

Annals of oncology, 2020-09, Vol.31, p.S736-S736

2020

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Synthesis of coumarin-substituted thiazolyl-pyrazolone derivatives via one-pot reaction

Journal of sulfur chemistry, 2010-12, Vol.31 (6), p.545-550

2010

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Safety, efficacy, and immune effects of intratumoral tilsotolimod in patients with refractory solid tumours: Updated results from ILLUMINATE-101

Annals of oncology, 2019-10, Vol.30, p.v487

2019

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1195P - Safety, efficacy, and immune effects of intratumoral tilsotolimod in patients with refractory solid tumours: Updated results from ILLUMINATE-101

Annals of oncology, 2019-10, Vol.30, p.v487-v487

2019

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1195PSafety, efficacy, and immune effects of intratumoral tilsotolimod in patients with refractory solid tumours: Updated results from ILLUMINATE-101

Annals of oncology, 2019-10, Vol.30 (Supplement_5)

2019

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1031P Tilsotolimod engages the TLR9 pathway to promote antigen presentation and type I IFN signaling in solid tumours

Annals of oncology, 2020-09, Vol.31, p.S711-S712

2020

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Methotrexate-resistant variants of human dihydrofolate reductase. Effects of Phe31 substitutions

The Journal of biological chemistry, 1994-04, Vol.269 (13), p.9547-9555

1994

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1245PDIntratumoral (IT) Injection of the TLR9 agonist tilsotolimod (IMO-2125) in combination with ipilimumab (ipi) triggers durable responses in PD-1 inhibitor refractory metastatic melanoma (rMM): Results from a multicenter, phase I/II study

Annals of oncology, 2018-10, Vol.29 (suppl_8)

2018

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Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers

The Journal of biological chemistry, 1995-03, Vol.270 (10), p.5057-5064

1995

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Mutations in the gene for human dihydrofolate reductase : an unlikely cause of clinical relapse in pediatric leukemia after therapy with methotrexate

Leukemia, 1996-03, Vol.10 (3), p.439-446

1996

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Dynamic Stall and Wake Effects on Trim and Stability of Hingeless Rotors with Experimental Correlation

Journal of the American Helicopter Society, 1997-10, Vol.42 (4), p.370-382

1997

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Flap-lag-torsion stability in hover and forward flight with three-dimensional wake

AIAA journal, 1996-01, Vol.34 (1), p.18-28

1996

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Activity of Human DNA Polymerases α and β with 2-Chloro-2′-deoxyadenosine 5′-Triphosphate as a Substrate and Quantitative Effects of Incorporation on Chain Extension

Archives of biochemistry and biophysics, 1993-04, Vol.302 (1), p.19-30

1993

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The pH dependence of the kinetic parameters of ketol acid reductoisomerase indicates a proton shuttle mechanism for alkyl migration

Archives of biochemistry and biophysics, 1992-05, Vol.294 (2), p.446-453

1992

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Intratumoral (IT) Injection of the TLR9 agonist tilsotolimod (IMO-2125) in combination with ipilimumab (ipi) triggers durable responses in PD-1 inhibitor refractory metastatic melanoma (rMM): Results from a multicenter, phase I/II study

A Facile One-Pot Expeditious Synthesis of Thiazolyl-pyrazolones

Bivalent IAP antagonists, but not monovalent IAP antagonists, inhibit TNF-mediated NF- κ B signaling by degrading TRAF2-associated cIAP1 in cancer cells

1543 Type 1 interferon signaling correlates with patient-reported itch in dermatomyositis

Tetrahydrobenzothiophene inhibitors of hepatitis C virus NS5B polymerase

Evaluating the Efficacy of Transresveratrol in Extraction Socket of Impacted Mandibular Third Molar: A Double-blind Study

In vivo model of adeno-associated virus vector persistence and rescue

IAP Antagonists Target cIAP1 to Induce TNFα-Dependent Apoptosis

LB1115 A double-blind, placebo-controlled, phase 2 trial of IMO-8400, a novel toll-like receptor 7/8/9 antagonist, in dermatomyositis

Mechanism of Action of a Pestivirus Antiviral Compound

1083MO Final results from ILLUMINATE-204, a phase I/II trial of intratumoral tilsotolimod in combination with ipilimumab in PD-1 inhibitor refractory advanced melanoma

Synthesis of coumarin-substituted thiazolyl-pyrazolone derivatives via one-pot reaction

Safety, efficacy, and immune effects of intratumoral tilsotolimod in patients with refractory solid tumours: Updated results from ILLUMINATE-101

1195P - Safety, efficacy, and immune effects of intratumoral tilsotolimod in patients with refractory solid tumours: Updated results from ILLUMINATE-101

1195PSafety, efficacy, and immune effects of intratumoral tilsotolimod in patients with refractory solid tumours: Updated results from ILLUMINATE-101

1031P Tilsotolimod engages the TLR9 pathway to promote antigen presentation and type I IFN signaling in solid tumours

Intravenous Doxycycline, Azithromycin, or Both for Severe Scrub Typhus

Methotrexate-resistant variants of human dihydrofolate reductase. Effects of Phe31 substitutions

1245PDIntratumoral (IT) Injection of the TLR9 agonist tilsotolimod (IMO-2125) in combination with ipilimumab (ipi) triggers durable responses in PD-1 inhibitor refractory metastatic melanoma (rMM): Results from a multicenter, phase I/II study

Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers

Mutations in the gene for human dihydrofolate reductase : an unlikely cause of clinical relapse in pediatric leukemia after therapy with methotrexate

Dynamic Stall and Wake Effects on Trim and Stability of Hingeless Rotors with Experimental Correlation

Flap-lag-torsion stability in hover and forward flight with three-dimensional wake

Activity of Human DNA Polymerases α and β with 2-Chloro-2′-deoxyadenosine 5′-Triphosphate as a Substrate and Quantitative Effects of Incorporation on Chain Extension

The pH dependence of the kinetic parameters of ketol acid reductoisomerase indicates a proton shuttle mechanism for alkyl migration

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