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Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability

International journal of molecular sciences, 2019-05, Vol.20 (11), p.2668

2019

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MAP4K3/GLK in autoimmune disease, cancer and aging

Journal of biomedical science, 2019-10, Vol.26 (1), p.82-82, Article 82

2019

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Induction of Interferon‐γ and Tissue Inflammation by Overexpression of Eosinophil Cationic Protein in T Cells and Exosomes

Arthritis & rheumatology (Hoboken, N.J.), 2022-01, Vol.74 (1), p.92-104

2022

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ACE2 in chronic disease and COVID-19: gene regulation and post-translational modification

Journal of biomedical science, 2023-08, Vol.30 (1), p.1-71, Article 71

2023

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Induction of DUSP14 ubiquitination by PRMT5‐mediated arginine methylation

The FASEB journal, 2018-06, Vol.32 (12), p.6760-6770

2018

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The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling

Nature communications, 2024-01, Vol.15 (1), p.532-532, Article 532

2024

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Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis

BMC medicine, 2023-02, Vol.21 (1), p.46-46, Article 46

2023

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DUSP8 induces TGF-β–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-α

The Journal of clinical investigation, 2023-11, Vol.133 (21), p.1-15

2023

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SARS‐CoV‐2 spike protein enhances MAP4K3/GLK‐induced ACE2 stability in COVID‐19

EMBO molecular medicine, 2022-09, Vol.14 (9), p.e15904-n/a

2022

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DUSP6 Deficiency Attenuates Neurodegeneration after Global Cerebral Ischemia

International journal of molecular sciences, 2023-04, Vol.24 (9), p.7690

2023

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HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance

Nature communications, 2014-08, Vol.5 (1), Article 4602

2014

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Enhanced expression of vascular endothelial growth factor‐A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis

Hepatology (Baltimore, Md.), 2009-06, Vol.49 (6), p.1962-1971

2009

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Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation

The Journal of immunology (1950), 2014-02, Vol.192 (4), p.1547-1557

2014

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Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck

Journal of biomedical science, 2024-03, Vol.31 (1), p.33-33, Article 33

2024

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Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases

International journal of molecular sciences, 2020-10, Vol.21 (20), p.7515

2020

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MAP4K Family Kinases in Immunity and Inflammation

Advances in immunology, 2016, Vol.129, p.277-314

2016

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Pathogenesis and mechanism of disease progression from hemophagocytic lymphohistiocytosis to Epstein–Barr virus‐associated T‐cell lymphoma: Nuclear factor‐κB pathway as a potential therapeutic target

Cancer science, 2007-09, Vol.98 (9), p.1281-1287

2007

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MAP4K4 and IL-6 + Th17 cells play important roles in non-obese type 2 diabetes

Journal of biomedical science, 2017-01, Vol.24 (1), p.4-4, Article 4

2017

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RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis

International journal of molecular sciences, 2018-09, Vol.19 (9), p.2646

2018

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MAP4K Family Kinases and DUSP Family Phosphatases in T-Cell Signaling and Systemic Lupus Erythematosus

Cells (Basel, Switzerland), 2019-11, Vol.8 (11), p.1433

2019

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Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker

BMC medicine, 2012-08, Vol.10 (1), p.84-84, Article 84

2012

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The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck

Nature communications, 2014-04, Vol.5 (1), p.3618-3618, Article 3618

2014

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Epstein-Barr virus LMP1 inhibits the expression of SAP gene and upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome

Blood, 2005-11, Vol.106 (9), p.3090-3096

2005

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MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1

Cancer research (Chicago, Ill.), 2019-10, Vol.79 (19), p.4978-4993

2019

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RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell

Biochimica et biophysica acta. Molecular cell research, 2018-02, Vol.1865 (2), p.259-272

2018

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Regulation of Dual-Specificity Phosphatase (DUSP) Ubiquitination and Protein Stability

MAP4K3/GLK in autoimmune disease, cancer and aging

Induction of Interferon‐γ and Tissue Inflammation by Overexpression of Eosinophil Cationic Protein in T Cells and Exosomes

ACE2 in chronic disease and COVID-19: gene regulation and post-translational modification

Induction of DUSP14 ubiquitination by PRMT5‐mediated arginine methylation

The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling

Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis

DUSP8 induces TGF-β–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-α

SARS‐CoV‐2 spike protein enhances MAP4K3/GLK‐induced ACE2 stability in COVID‐19

DUSP6 Deficiency Attenuates Neurodegeneration after Global Cerebral Ischemia

HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance

Enhanced expression of vascular endothelial growth factor‐A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis

Dual-specificity phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation

Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck

Structural Insights into the Active Site Formation of DUSP22 in N-loop-containing Protein Tyrosine Phosphatases

MAP4K Family Kinases in Immunity and Inflammation

Pathogenesis and mechanism of disease progression from hemophagocytic lymphohistiocytosis to Epstein–Barr virus‐associated T‐cell lymphoma: Nuclear factor‐κB pathway as a potential therapeutic target

MAP4K4 and IL-6 + Th17 cells play important roles in non-obese type 2 diabetes

RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis

MAP4K Family Kinases and DUSP Family Phosphatases in T-Cell Signaling and Systemic Lupus Erythematosus

Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker

The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck

Epstein-Barr virus LMP1 inhibits the expression of SAP gene and upregulates Th1 cytokines in the pathogenesis of hemophagocytic syndrome

MAP4K3/GLK Promotes Lung Cancer Metastasis by Phosphorylating and Activating IQGAP1

RBM4-SRSF3-MAP4K4 splicing cascade modulates the metastatic signature of colorectal cancer cell

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