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Engineering extrinsic disorder to control protein activity in living cells

Science (American Association for the Advancement of Science), 2016-12, Vol.354 (6318), p.1441-1444

2016

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Artificial intelligence-assisted fast screening cervical high grade squamous intraepithelial lesion and squamous cell carcinoma diagnosis and treatment planning

Scientific reports, 2021-08, Vol.11 (1), p.16244-16244, Article 16244

2021

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Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells

Stem cell reports, 2021-12, Vol.16 (12), p.3076-3092

2021

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Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (34), p.12420-12425

2014

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Dissecting motility signaling through activation of specific Src-effector complexes

Nature chemical biology, 2014-04, Vol.10 (4), p.286

2014

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An optogenetic tool for the activation of endogenous diaphanous-related formins induces thickening of stress fibers without an increase in contractility

Cytoskeleton (Hoboken, N.J.), 2013-07, Vol.70 (7), p.394-407

2013

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3D-Suspension culture platform for high throughput screening of neurotoxic chemicals using LUHMES dopaminergic neurons

SLAS discovery, 2024-04, Vol.29 (3), p.100143-100143, Article 100143

2024

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Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (51), p.19308-19313

2006

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Stem Cell-Derived Endothelial Cell Model that Responds to Tobacco Smoke Like Primary Endothelial Cells

Chemical research in toxicology, 2020-03, Vol.33 (3), p.751-763

2020

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The MT1G Gene in LUHMES Neurons Is a Sensitive Biomarker of Neurotoxicity

Neurotoxicity research, 2020-12, Vol.38 (4), p.967-978

2020

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Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail

Nature protocols, 2023-01, Vol.18 (1), p.58-80

2023

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Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies

Environmental health perspectives, 2018-07, Vol.126 (7), p.077010-077010

2018

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Stress-free cell aggregation by using the CEPT cocktail enhances embryoid body and organoid fitness

Biofabrication, 2024-01, Vol.16 (1), p.15016

2024

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Scalable generation of sensory neurons from human pluripotent stem cells

Stem cell reports, 2023-04, Vol.18 (4), p.1030-1047

2023

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A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells

Stem cell reports, 2023-08, Vol.18 (8), p.1701-1720

2023

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SEQUIN is an R/Shiny framework for rapid and reproducible analysis of RNA-seq data

Cell reports methods, 2023-03, Vol.3 (3), p.100420-100420, Article 100420

2023

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In Vitro Exposure Systems and Dosimetry Assessment Tools for Inhaled Tobacco Products: Workshop Proceedings, Conclusions and Paths Forward for In Vitro Model Use

Alternatives to laboratory animals, 2017-07, Vol.45 (3), p.117-158

2017

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User-friendly tools for quantifying the dynamics of cellular morphology and intracellular protein clusters

Methods in Cell Biology, 2014, Vol.123, p.409-427

2014

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Identification of an HptB-mediated multi-step phosphorelay in Pseudomonas aeruginosa PAO1

Research in microbiology, 2006-03, Vol.157 (2), p.169-175

2006

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Generation of a Light Inhibited Src Kinase through Insertion of LOV into the Catalytic Domain

Biophysical journal, 2013-01, Vol.104 (2), p.679a-679a

2013

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Chapter 22 - User-friendly tools for quantifying the dynamics of cellular morphology and intracellular protein clusters

Methods in cell biology, 2014-01, Vol.123, p.409-427

2014

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Engineered Manipulation of Signaling Networks: Control of Kinase Activation and Interactions Dissects Parallel Src Pathways

Biophysical journal, 2013-01, Vol.104 (2), p.161a-161a

2013

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New Tools for Activation of Src Family Isoforms In Vivo Demonstrate Specific Roles for Each Isoform in Cell Motility

Biophysical journal, 2013-01, Vol.104 (2), p.161a-161a

2013

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Dissecting the role of kinase isoforms using new tools for activation and inactivation of kinases in vivo

Chu, Pei-Hsuan

2013

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Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH

Proceedings of the National Academy of Sciences - PNAS, 2006-12, Vol.103 (51), p.19308-19313

2006

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Engineering extrinsic disorder to control protein activity in living cells

Artificial intelligence-assisted fast screening cervical high grade squamous intraepithelial lesion and squamous cell carcinoma diagnosis and treatment planning

Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells

Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms

Dissecting motility signaling through activation of specific Src-effector complexes

An optogenetic tool for the activation of endogenous diaphanous-related formins induces thickening of stress fibers without an increase in contractility

3D-Suspension culture platform for high throughput screening of neurotoxic chemicals using LUHMES dopaminergic neurons

Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2

Stem Cell-Derived Endothelial Cell Model that Responds to Tobacco Smoke Like Primary Endothelial Cells

The MT1G Gene in LUHMES Neurons Is a Sensitive Biomarker of Neurotoxicity

Efficient and safe single-cell cloning of human pluripotent stem cells using the CEPT cocktail

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies

Stress-free cell aggregation by using the CEPT cocktail enhances embryoid body and organoid fitness

Scalable generation of sensory neurons from human pluripotent stem cells

A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells

SEQUIN is an R/Shiny framework for rapid and reproducible analysis of RNA-seq data

In Vitro Exposure Systems and Dosimetry Assessment Tools for Inhaled Tobacco Products: Workshop Proceedings, Conclusions and Paths Forward for In Vitro Model Use

User-friendly tools for quantifying the dynamics of cellular morphology and intracellular protein clusters

Identification of an HptB-mediated multi-step phosphorelay in Pseudomonas aeruginosa PAO1

Generation of a Light Inhibited Src Kinase through Insertion of LOV into the Catalytic Domain

Chapter 22 - User-friendly tools for quantifying the dynamics of cellular morphology and intracellular protein clusters

Engineered Manipulation of Signaling Networks: Control of Kinase Activation and Interactions Dissects Parallel Src Pathways

New Tools for Activation of Src Family Isoforms In Vivo Demonstrate Specific Roles for Each Isoform in Cell Motility

Dissecting the role of kinase isoforms using new tools for activation and inactivation of kinases in vivo

Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH

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