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Design, Synthesis, and Antimicrobial Activity of 6-O-Substituted Ketolides Active against Resistant Respiratory Tract Pathogens

Journal of medicinal chemistry, 2000-03, Vol.43 (6), p.1045-1049

2000

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New Directions in Antibacterial Research

Journal of medicinal chemistry, 1996-09, Vol.39 (20), p.3853-3874

1996

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Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug-DNA binding model

Biochemistry (Easton), 1989-05, Vol.28 (9), p.3886-3894

1989

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Synthesis and Antimicrobial Activity of 4H-4-Oxoquinolizine Derivatives: Consequences of Structural Modification at the C-8 Position

Journal of medicinal chemistry, 1999-10, Vol.42 (20), p.4202-4213

1999

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Synthesis and Structure−Activity Relationships of 2-Pyridones: A Novel Series of Potent DNA Gyrase Inhibitors as Antibacterial Agents

Journal of medicinal chemistry, 1996-08, Vol.39 (16), p.3070-3088

1996

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Quinobenoxazines: A Class of Novel Antitumor Quinolones and Potent Mammalian DNA Topoisomerase II Catalytic Inhibitors

Biochemistry (Easton), 1994-09, Vol.33 (37), p.11333-11339

1994

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Novel Erythromycin Derivatives with Aryl Groups Tethered to the C-6 Position Are Potent Protein Synthesis Inhibitors and Active against Multidrug-Resistant Respiratory Pathogens

Journal of medicinal chemistry, 2001-11, Vol.44 (24), p.4137-4156

2001

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A convenient and highly chemoselective method for the reductive acetylation of azides

Journal of organic chemistry, 1988-04, Vol.53 (7), p.1580-1582

1988

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Synthesis, antibacterial activities, and pharmacological properties of enantiomers of temafloxacin hydrochloride

Journal of medicinal chemistry, 1991-01, Vol.34 (1), p.168-174

1991

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Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride

Journal of medicinal chemistry, 1988-08, Vol.31 (8), p.1586-1590

1988

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Anhydrolide Macrolides. 1. Synthesis and Antibacterial Activity of 2,3-Anhydro-6-O-methyl 11,12-Carbamate Erythromycin A Analogues

Journal of medicinal chemistry, 1998-05, Vol.41 (10), p.1651-1659

1998

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Recent progress in novel macrolides, quinolones, and 2-pyridones to overcome bacterial resistance

Medicinal research reviews, 1999-11, Vol.19 (6), p.497-520

Chu, Daniel T. W.

1999

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Syntheses and antibacterial activity of novel 6-fluoro-7-(gem-disubstituted piperazin-1-yl)-quinolines

Canadian journal of chemistry, 1992-05, Vol.70 (5), p.1328-1337

1992

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Anhydrolide Macrolides. 2. Synthesis and Antibacterial Activity of 2,3-Anhydro-6-O-methyl 11,12-Carbazate Erythromycin A Analogues

Journal of medicinal chemistry, 1998-05, Vol.41 (10), p.1660-1670

1998

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Preparation and in vitro and in vivo evaluation of quinolones with selective activity against Gram-positive organisms

Journal of medicinal chemistry, 1992-04, Vol.35 (8), p.1392-1398

1992

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Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents

Journal of medicinal chemistry, 1985-11, Vol.28 (11), p.1558-1564

1985

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Design, synthesis, and properties of (4S)-7-(4-amino-2-substituted-pyrrolidin-1-yl)quinolone-3-carboxylic acids

Journal of medicinal chemistry, 1988-08, Vol.31 (8), p.1598-1611

1988

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Section Review Anti-infectives: The future role of quinolones

Expert opinion on therapeutic patents, 1996-08, Vol.6 (8), p.711-737

TW Chu, Daniel

1996

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Synthesis and structure-activity relationships of new arylfluoronaphthyridine antibacterial agents

Journal of medicinal chemistry, 1986-11, Vol.29 (11), p.2363-2369

1986

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Synthesis and biological activity of benzothiazolo[3,2-a]quinolone antibacterial agents

Journal of medicinal chemistry, 1986-08, Vol.29 (8), p.1531-1534

1986

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Synthesis and structure-activity relationship of 1-aryl-6,8-difluoroquinolone antibacterial agents

Journal of medicinal chemistry, 1987-03, Vol.30 (3), p.504-509

1987

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The synthesis and antibacterial activities of quinolones containing five- and six-membered heterocyclic substituents at the 7-position

Journal of medicinal chemistry, 1990-04, Vol.33 (4), p.1246-1252

1990

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Recent progress in novel macrolides, quinolones, and 2‐pyridones to overcome bacterial resistance

Medicinal research reviews, 1999-11, Vol.19 (6), p.497-520

Chu, Daniel T. W.

1999

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Synthesis of 4-oxo-4H-quino[2,3,4-i,j][1,4]-benoxazine-5-carboxylic acid derivatives

Journal of heterocyclic chemistry, 1987-03, Vol.24 (2), p.453-456

1987

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3-Keto-11,12-carbazate Derivatives of 6-0-Methylerythromycin A Synthesis and In Vitro Activity

Journal of antibiotics, 1996, Vol.49 (5), p.465-477

1996

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Design, Synthesis, and Antimicrobial Activity of 6-O-Substituted Ketolides Active against Resistant Respiratory Tract Pathogens

New Directions in Antibacterial Research

Mechanism of inhibition of DNA gyrase by quinolone antibacterials: a cooperative drug-DNA binding model

Synthesis and Antimicrobial Activity of 4H-4-Oxoquinolizine Derivatives: Consequences of Structural Modification at the C-8 Position

Synthesis and Structure−Activity Relationships of 2-Pyridones: A Novel Series of Potent DNA Gyrase Inhibitors as Antibacterial Agents

Quinobenoxazines: A Class of Novel Antitumor Quinolones and Potent Mammalian DNA Topoisomerase II Catalytic Inhibitors

Novel Erythromycin Derivatives with Aryl Groups Tethered to the C-6 Position Are Potent Protein Synthesis Inhibitors and Active against Multidrug-Resistant Respiratory Pathogens

A convenient and highly chemoselective method for the reductive acetylation of azides

Synthesis, antibacterial activities, and pharmacological properties of enantiomers of temafloxacin hydrochloride

Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride

Anhydrolide Macrolides. 1. Synthesis and Antibacterial Activity of 2,3-Anhydro-6-O-methyl 11,12-Carbamate Erythromycin A Analogues

Recent progress in novel macrolides, quinolones, and 2-pyridones to overcome bacterial resistance

Syntheses and antibacterial activity of novel 6-fluoro-7-(gem-disubstituted piperazin-1-yl)-quinolines

Anhydrolide Macrolides. 2. Synthesis and Antibacterial Activity of 2,3-Anhydro-6-O-methyl 11,12-Carbazate Erythromycin A Analogues

Preparation and in vitro and in vivo evaluation of quinolones with selective activity against Gram-positive organisms

Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents

Design, synthesis, and properties of (4S)-7-(4-amino-2-substituted-pyrrolidin-1-yl)quinolone-3-carboxylic acids

Section Review Anti-infectives: The future role of quinolones

Synthesis and structure-activity relationships of new arylfluoronaphthyridine antibacterial agents

Synthesis and biological activity of benzothiazolo[3,2-a]quinolone antibacterial agents

Synthesis and structure-activity relationship of 1-aryl-6,8-difluoroquinolone antibacterial agents

The synthesis and antibacterial activities of quinolones containing five- and six-membered heterocyclic substituents at the 7-position

Recent progress in novel macrolides, quinolones, and 2‐pyridones to overcome bacterial resistance

Synthesis of 4-oxo-4H-quino[2,3,4-i,j][1,4]-benoxazine-5-carboxylic acid derivatives

3-Keto-11,12-carbazate Derivatives of 6-0-Methylerythromycin A Synthesis and In Vitro Activity

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