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Intrinsic Efficacy of Opioid Ligands and Its Importance for Apparent Bias, Operational Analysis, and Therapeutic Window

Molecular pharmacology, 2020-10, Vol.98 (4), p.410-424

2020

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Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to human

British journal of pharmacology, 2011-10, Vol.164 (4), p.1322-1334

2011

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Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists

Science signaling, 2020-03, Vol.13 (625)

2020

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Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons

British journal of pharmacology, 2012-03, Vol.165 (6), p.1704-1716

2012

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Challenges for opioid receptor nomenclature: IUPHAR Review 9

British journal of pharmacology, 2015-01, Vol.172 (2), p.317-323

2015

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Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (46), p.12309-12314

2017

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Plasticity in striatopallidal projection neurons mediates the acquisition of habitual actions

The European journal of neuroscience, 2015-08, Vol.42 (4), p.2097-2104

2015

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Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area

The Journal of physiology, 2011-08, Vol.589 (15), p.3775-3787

2011

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Glycine transport inhibitors for the treatment of pain

Trends in pharmacological sciences (Regular ed.), 2014-08, Vol.35 (8), p.423-430

2014

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Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?

Toxins, 2015-09, Vol.7 (10), p.3916-3932

2015

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Cellular and Synaptic Adaptations Mediating Opioid Dependence

Physiological reviews, 2001-01, Vol.81 (1), p.299-343

2001

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The Light Touch of Delta Opioid Receptors

Neuron (Cambridge, Mass.), 2014-03, Vol.81 (6), p.1220-1222

2014

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Morphine‐induced respiratory depression is independent of β‐arrestin2 signalling

British journal of pharmacology, 2020-07, Vol.177 (13), p.2923-2931

2020

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Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor

Trends in pharmacological sciences (Regular ed.), 2020-12, Vol.41 (12), p.947-959

2020

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Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine-Assisted Folding

Angewandte Chemie (International ed.), 2011-07, Vol.50 (29), p.6527-6529

International ed. in English, 2011

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Glycinergic Modulation of Pain in Behavioral Animal Models

Frontiers in pharmacology, 2022-05, Vol.13, p.860903-860903

2022

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Conus venom peptide pharmacology

Pharmacological reviews, 2012-04, Vol.64 (2), p.259-298

2012

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Opioid overdose and tolerance: is the recruitment of β-arrestin to the µ-receptor involved?

Neuropsychopharmacology (New York, N.Y.), 2021-12, Vol.46 (13), p.2226-2227

2021

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Switch to Ca2+-permeable AMPA and reduced NR2B NMDA receptor-mediated neurotransmission at dorsal horn nociceptive synapses during inflammatory pain in the rat

The Journal of physiology, 2008-01, Vol.586 (2), p.515-527

2008

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Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels

Frontiers in pharmacology, 2021-01, Vol.11, p.633679-633679

2021

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Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance

Pharmacological reviews, 2013-01, Vol.65 (1), p.223-254

2013

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Conotoxins That Could Provide Analgesia through Voltage Gated Sodium Channel Inhibition

Toxins, 2015-12, Vol.7 (12), p.5386-5407

2015

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Opioid receptor modulation of GABAergic and serotonergic spinally projecting neurons of the rostral ventromedial medulla in mice

Journal of neurophysiology, 2011-08, Vol.106 (2), p.731-740

2011

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The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity

Scientific reports, 2017-04, Vol.7 (1), p.974-15, Article 974

2017

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Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus In vitro

The Journal of physiology, 2002-09, Vol.543 (2), p.531-540

2002

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Intrinsic Efficacy of Opioid Ligands and Its Importance for Apparent Bias, Operational Analysis, and Therapeutic Window

Analysis of opioid efficacy, tolerance, addiction and dependence from cell culture to human

Low intrinsic efficacy for G protein activation can explain the improved side effect profiles of new opioid agonists

Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons

Challenges for opioid receptor nomenclature: IUPHAR Review 9

Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

Plasticity in striatopallidal projection neurons mediates the acquisition of habitual actions

Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area

Glycine transport inhibitors for the treatment of pain

Conotoxin Interactions with α9α10-nAChRs: Is the α9α10-Nicotinic Acetylcholine Receptor an Important Therapeutic Target for Pain Management?

Cellular and Synaptic Adaptations Mediating Opioid Dependence

The Light Touch of Delta Opioid Receptors

Morphine‐induced respiratory depression is independent of β‐arrestin2 signalling

Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor

Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine-Assisted Folding

Glycinergic Modulation of Pain in Behavioral Animal Models

Conus venom peptide pharmacology

Opioid overdose and tolerance: is the recruitment of β-arrestin to the µ-receptor involved?

Switch to Ca2+-permeable AMPA and reduced NR2B NMDA receptor-mediated neurotransmission at dorsal horn nociceptive synapses during inflammatory pain in the rat

Spider Venom Peptide Pn3a Inhibition of Primary Afferent High Voltage-Activated Calcium Channels

Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance

Conotoxins That Could Provide Analgesia through Voltage Gated Sodium Channel Inhibition

Opioid receptor modulation of GABAergic and serotonergic spinally projecting neurons of the rostral ventromedial medulla in mice

The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity

Capsaicin activation of glutamatergic synaptic transmission in the rat locus coeruleus In vitro

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