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The Need for Restructuring the Disordered Science of Amorphous Drug Formulations

Pharmaceutical research, 2017-09, Vol.34 (9), p.1754-1772

2017

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Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs

Pharmaceutical research, 2009-08, Vol.26 (8), p.1816-1831

2009

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Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations

Pharmaceutical research, 2018-04, Vol.35 (4), p.74-11, Article 74

2018

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Computational prediction of drug solubility in water-based systems: Qualitative and quantitative approaches used in the current drug discovery and development setting

International journal of pharmaceutics, 2018-04, Vol.540 (1-2), p.185-193

2018

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Computational prediction of formulation strategies for beyond-rule-of-5 compounds

Advanced drug delivery reviews, 2016-06, Vol.101, p.6-21

2016

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Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations

Pharmaceutical research, 2020-06, Vol.37 (6), p.99-99, Article 99

2020

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In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug–Drug Interactions

Pharmaceutical research, 2012-02, Vol.29 (2), p.411-426

2012

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Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid

The journal of physical chemistry. B, 2017-12, Vol.121 (48), p.10869-10881

2017

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Structural Requirements for Drug Inhibition of the Liver Specific Human Organic Cation Transport Protein 1

Journal of medicinal chemistry, 2008-10, Vol.51 (19), p.5932-5942

2008

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Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison

Journal of computer-aided molecular design, 2024-12, Vol.38 (1), p.5-5, Article 5

2024

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Computational Predictions of Glass-Forming Ability and Crystallization Tendency of Drug Molecules

Molecular pharmaceutics, 2014-09, Vol.11 (9), p.3123-3132

2014

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Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers

Molecular pharmaceutics, 2020-11, Vol.17 (11), p.4226-4240

2020

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Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations

Molecular pharmaceutics, 2018-10, Vol.15 (10), p.4733-4744

2018

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Contemporary Formulation Development for Inhaled Pharmaceuticals

Journal of pharmaceutical sciences, 2021-01, Vol.110 (1), p.66-86

2021

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Tools for Early Prediction of Drug Loading in Lipid-Based Formulations

Molecular pharmaceutics, 2016-01, Vol.13 (1), p.251-261

2016

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Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine

Langmuir, 2021-08, Vol.37 (33), p.10200-10213

2021

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EGFR activation limits the response of liver cancer to lenvatinib

Nature (London), 2021-07, Vol.595 (7869), p.730-734

2021

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Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set

Molecular pharmaceutics, 2024-10, Vol.21 (10), p.5261-5271

2024

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Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs

Molecular pharmaceutics, 2023-01, Vol.20 (1), p.451-460

2023

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Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

European journal of pharmaceutical sciences, 2019-09, Vol.137, p.104967-104967, Article 104967

2019

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Experiences and Translatability of In Vitro and In Vivo Models to Evaluate Caprate as a Permeation Enhancer

Molecular pharmaceutics, 2024, Vol.21 (1), p.313-324

2024

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Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations

Journal of controlled release, 2016-05, Vol.229, p.172-182

2016

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Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat

Molecular pharmaceutics, 2022-01, Vol.19 (1), p.200-212

2022

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Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations

Molecular pharmaceutics, 2021-11, Vol.18 (11), p.4079-4089

2021

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50 years of oral lipid-based formulations: Provenance, progress and future perspectives

Advanced drug delivery reviews, 2016-06, Vol.101, p.167-194

2016

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The Need for Restructuring the Disordered Science of Amorphous Drug Formulations

Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs

Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations

Computational prediction of drug solubility in water-based systems: Qualitative and quantitative approaches used in the current drug discovery and development setting

Computational prediction of formulation strategies for beyond-rule-of-5 compounds

Suitability of Artificial Membranes in Lipolysis-Permeation Assays of Oral Lipid-Based Formulations

In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug–Drug Interactions

Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid

Structural Requirements for Drug Inhibition of the Liver Specific Human Organic Cation Transport Protein 1

Molecular dynamics study on micelle-small molecule interactions: developing a strategy for an extensive comparison

Computational Predictions of Glass-Forming Ability and Crystallization Tendency of Drug Molecules

Influence of Bile Composition on Membrane Incorporation of Transient Permeability Enhancers

Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations

Contemporary Formulation Development for Inhaled Pharmaceuticals

Tools for Early Prediction of Drug Loading in Lipid-Based Formulations

Investigation of Self-Emulsifying Drug-Delivery System Interaction with a Biomimetic Membrane under Conditions Relevant to the Small Intestine

EGFR activation limits the response of liver cancer to lenvatinib

Effect of Data Quality and Data Quantity on the Estimation of Intrinsic Solubility: Analysis Based on a Single-Source Data Set

Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs

Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

Experiences and Translatability of In Vitro and In Vivo Models to Evaluate Caprate as a Permeation Enhancer

Compromised in vitro dissolution and membrane transport of multidrug amorphous formulations

Impact of Intestinal Concentration and Colloidal Structure on the Permeation-Enhancing Efficiency of Sodium Caprate in the Rat

Impact of Simulated Intestinal Fluids on Dissolution, Solution Chemistry, and Membrane Transport of Amorphous Multidrug Formulations

50 years of oral lipid-based formulations: Provenance, progress and future perspectives

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