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The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

Nature communications, 2021-01, Vol.12 (1), p.4-13, Article 4

2021

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Nonsteroidal Anti-inflammatory Drugs Dampen the Cytokine and Antibody Response to SARS-CoV-2 Infection

Journal of virology, 2021-03, Vol.95 (7)

2021

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Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury

Cell stem cell, 2018-05, Vol.22 (5), p.668-683.e6

2018

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AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

Nature neuroscience, 2017-10, Vol.20 (10), p.1329-1341

2017

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A web tool for the design of prime-editing guide RNAs

Nature biomedical engineering, 2021-02, Vol.5 (2), p.190-194

2021

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Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity

Nature immunology, 2019-11, Vol.20 (11), p.1494-1505

2019

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LRRC15 inhibits SARS-CoV-2 cellular entry in trans

PLoS biology, 2022-10, Vol.20 (10), p.e3001805

2022

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Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion

Nature communications, 2018-05, Vol.9 (1), p.1903-9, Article 1903

2018

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DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner

PLoS biology, 2023-06, Vol.21 (6), p.e3002097

2023

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Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617

Nature communications, 2022-03, Vol.13 (1), p.1638-18, Article 1638

2022

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Phenotypic evaluation of deep learning models for classifying germline variant pathogenicity

NPJ precision oncology, 2024-10, Vol.8 (1), p.235-7, Article 235

2024

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Mutations in IFN-γ signaling genes sensitize tumors to immune checkpoint blockade

Cancer cell, 2023-04, Vol.41 (4), p.651-652

2023

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On the Absence of Sound

Journal of clinical oncology, 2021-11, Vol.39 (33), p.3759-3759

Chow, Ryan D

2021

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Sno-derived RNAs are prevalent molecular markers of cancer immunity

Oncogene, 2018-12, Vol.37 (50), p.6442-6462

2018

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In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma

Nature biotechnology, 2019-11, Vol.37 (11), p.1302-1313

2019

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IL17A mRNA Staining Distinguishes Palmoplantar Psoriasis from Hyperkeratotic Palmoplantar Eczema in Diagnostic Skin Biopsies

JID innovations, 2023-07, Vol.3 (4), p.100189-100189, Article 100189

2023

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Cancer CRISPR Screens In Vivo

Trends in Cancer, 2018-05, Vol.4 (5), p.349-358

2018

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A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

Cell metabolism, 2022-04, Vol.34 (4), p.595-614.e14

2022

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Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Cell, 2019-08, Vol.178 (5), p.1189-1204.e23

2019

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Epithelial cell plasticity: breaking boundaries and changing landscapes

EMBO reports, 2021-07, Vol.22 (7), p.e51921-n/a

2021

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Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity

Developmental cell, 2018-03, Vol.44 (6), p.679-693.e5

2018

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Distinct Mechanisms of Mismatch-Repair Deficiency Delineate Two Modes of Response to Anti-PD-1 Immunotherapy in Endometrial Carcinoma

Cancer discovery, 2023-02, Vol.13 (2), p.312-331

2023

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CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade

Cancer discovery, 2020-12, Vol.10 (12), p.1912-1933

2020

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Massively parallel knock-in engineering of human T cells

Nature biotechnology, 2023-09, Vol.41 (9), p.1239-1255

2023

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The aging transcriptome and cellular landscape of the human lung in relation to SARS-CoV-2

Nonsteroidal Anti-inflammatory Drugs Dampen the Cytokine and Antibody Response to SARS-CoV-2 Infection

Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury

AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma

A web tool for the design of prime-editing guide RNAs

Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity

LRRC15 inhibits SARS-CoV-2 cellular entry in trans

Programmable sequential mutagenesis by inducible Cpf1 crRNA array inversion

DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner

Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617

Phenotypic evaluation of deep learning models for classifying germline variant pathogenicity

Mutations in IFN-γ signaling genes sensitize tumors to immune checkpoint blockade

On the Absence of Sound

Sno-derived RNAs are prevalent molecular markers of cancer immunity

In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma

IL17A mRNA Staining Distinguishes Palmoplantar Psoriasis from Hyperkeratotic Palmoplantar Eczema in Diagnostic Skin Biopsies

Cancer CRISPR Screens In Vivo

A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy

Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells

Epithelial cell plasticity: breaking boundaries and changing landscapes

Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity

Distinct Mechanisms of Mismatch-Repair Deficiency Delineate Two Modes of Response to Anti-PD-1 Immunotherapy in Endometrial Carcinoma

CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade

Massively parallel knock-in engineering of human T cells

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