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A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes

Proceedings of the National Academy of Sciences - PNAS, 2022-08, Vol.119 (31), p.e2120028119-e2120028119

2022

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Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands

Nature, 2007-05, Vol.447 (7143), p.482-486

2007

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Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.14840-14845

2014

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Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining

Nature communications, 2016-08, Vol.7 (1), p.12614-12614, Article 12614

2016

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Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development

PloS one, 2014-11, Vol.9 (11), p.e112882-e112882

2014

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Bystander CD4+ T cells infiltrate human tumors and are phenotypically distinct

Oncoimmunology, 2022-12, Vol.11 (1), p.2012961-2012961

2022

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Characterizing T cell responses to enzymatically modified beta cell neo-epitopes

Frontiers in immunology, 2023-01, Vol.13, p.1015855-1015855

2023

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Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells

Cellular immunology, 2019-01, Vol.335, p.68-75

2019

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Recognition of Posttranslationally Modified GAD65 Epitopes in Subjects With Type 1 Diabetes

Diabetes (New York, N.Y.), 2014-09, Vol.63 (9), p.3033-3040

2014

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Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma

The Journal of clinical investigation, 2018-04, Vol.128 (4), p.1563-1568

2018

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Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial

Gastroenterology (New York, N.Y. 1943), 2021-02, Vol.160 (3), p.720-733.e8

2021

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Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB104:01

Diabetes (New York, N.Y.), 2020-07, Vol.69 (7), p.1492-1502

2020

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Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense

The Journal of immunology (1950), 2019-05, Vol.202 (9), p.2558-2569

2019

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The N-terminal domain of Escherichia coli ClpB enhances chaperone function

FEBS letters, 2005-08, Vol.579 (20), p.4242-4248

2005

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Ontogeny of different subsets of yellow fever virus-specific circulatory CXCR5+ CD4+ T cells after yellow fever vaccination

Scientific reports, 2020-09, Vol.10 (1), p.15686-15686, Article 15686

2020

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Coordinated synthesis of the two ClpB isoforms improves the ability of Escherichia coli to survive thermal stress

FEBS letters, 2005-08, Vol.579 (20), p.4235-4241

2005

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Increased islet antigen-specific regulatory and effector CD4 + T cells in healthy individuals with the type 1 diabetes-protective haplotype

Science immunology, 2020-02, Vol.5 (44)

2020

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Human CD4 + T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain

Cancer immunology research, 2019-10, Vol.7 (10), p.1727-1739

2019

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Differential binding of pyruvate dehydrogenase complex-E2 epitopes by DRB108:01 and DRB111:01 Is predicted by their structural motifs and correlates with disease risk

The Journal of immunology (1950), 2013-05, Vol.190 (9), p.4516-4524

2013

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Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes

Science advances, 2019-08, Vol.5 (8), p.eaaw9336-eaaw9336

2019

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DRB112:01 presents a unique subset of epitopes by preferring aromatics in pocket 9

Molecular immunology, 2012-02, Vol.50 (1-2), p.26-34

2012

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Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4 + T Cells in Patients With Type 1 Diabetes

Diabetes (New York, N.Y.), 2018-07, Vol.67 (7), p.1356-1368

2018

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938-P: A Human Gut Commensal, Parabacteroides Distasonis, Enhances Type 1 Diabetes Autoimmunity via Molecular Mimicry

Diabetes (New York, N.Y.), 2021-06, Vol.70 (Supplement_1)

2021

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Identification of Cross Reactive Insulin Immunogenic Epitopes from Commensal Gut Microbes

Diabetes (New York, N.Y.), 2018-07, Vol.67 (Supplement_1)

2018

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Ana o 1 and Ana o 2 cashew allergens share cross-reactive CD4+ T cell epitopes with other tree nuts

Clinical and experimental allergy, 2016-06, Vol.46 (6), p.871-883

2016

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A gut microbial peptide and molecular mimicry in the pathogenesis of type 1 diabetes

Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands

Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes

Efficient ex vivo analysis of CD4+ T-cell responses using combinatorial HLA class II tetramer staining

Assessment of CD4+ T cell responses to glutamic acid decarboxylase 65 using DQ8 tetramers reveals a pathogenic role of GAD65 121-140 and GAD65 250-266 in T1D development

Bystander CD4+ T cells infiltrate human tumors and are phenotypically distinct

Characterizing T cell responses to enzymatically modified beta cell neo-epitopes

Analysis of pancreatic beta cell specific CD4+ T cells reveals a predominance of proinsulin specific cells

Recognition of Posttranslationally Modified GAD65 Epitopes in Subjects With Type 1 Diabetes

Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma

Evaluating Responses to Gluten Challenge: A Randomized, Double-Blind, 2-Dose Gluten Challenge Trial

Hybrid Insulin Peptides Are Recognized by Human T Cells in the Context of DRB104:01

Epitope Selection for HLA-DQ2 Presentation: Implications for Celiac Disease and Viral Defense

The N-terminal domain of Escherichia coli ClpB enhances chaperone function

Ontogeny of different subsets of yellow fever virus-specific circulatory CXCR5+ CD4+ T cells after yellow fever vaccination

Coordinated synthesis of the two ClpB isoforms improves the ability of Escherichia coli to survive thermal stress

Increased islet antigen-specific regulatory and effector CD4 + T cells in healthy individuals with the type 1 diabetes-protective haplotype

Human CD4 + T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain

Differential binding of pyruvate dehydrogenase complex-E2 epitopes by DRB108:01 and DRB111:01 Is predicted by their structural motifs and correlates with disease risk

Discriminative T cell recognition of cross-reactive islet-antigens is associated with HLA-DQ8 transdimer-mediated autoimmune diabetes

DRB112:01 presents a unique subset of epitopes by preferring aromatics in pocket 9

Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4 + T Cells in Patients With Type 1 Diabetes

938-P: A Human Gut Commensal, Parabacteroides Distasonis, Enhances Type 1 Diabetes Autoimmunity via Molecular Mimicry

Identification of Cross Reactive Insulin Immunogenic Epitopes from Commensal Gut Microbes

Ana o 1 and Ana o 2 cashew allergens share cross-reactive CD4+ T cell epitopes with other tree nuts

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