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Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases

Biochemistry (Easton), 2017-04, Vol.56 (14), p.2010-2023

2017

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Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase

ACS chemical biology, 2016-04, Vol.11 (4), p.889-899

2016

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Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes

Biochemistry (Easton), 2017-10, Vol.56 (43), p.5798-5811

2017

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Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization–Fragmentation Reaction Sequence

Biochemistry (Easton), 2015-12, Vol.54 (48), p.7142-7155

2015

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Structure of 2-Methylisoborneol Synthase from Streptomyces coelicolor and Implications for the Cyclization of a Noncanonical C-Methylated Monoterpenoid Substrate

Biochemistry (Easton), 2012-04, Vol.51 (14), p.3011-3020

2012

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Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi-Isozizaene Synthase

Biochemistry (Easton), 2014-02, Vol.53 (7), p.1155-1168

2014

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Genome Mining in Streptomyces avermitilis: Cloning and Characterization of SAV_76, the Synthase for a New Sesquiterpene, Avermitilol

Journal of the American Chemical Society, 2010-07, Vol.132 (26), p.8850-8851

2010

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Structure of Geranyl Diphosphate C-Methyltransferase from Streptomyces coelicolor and Implications for the Mechanism of Isoprenoid Modification

Biochemistry (Easton), 2012-04, Vol.51 (14), p.3003-3010

2012

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Cloning and characterization of Pfl_1841, a 2-methylenebornane synthase in Pseudomonas fluorescens PfO-1

Tetrahedron, 2011-09, Vol.67 (35), p.6627-6632

2011

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The T296V Mutant of Amorpha-4,11-diene Synthase Is Defective in Allylic Diphosphate Isomerization but Retains the Ability To Cyclize the Intermediate (3R)‑Nerolidyl Diphosphate to Amorpha-4,11-diene

Biochemistry (Easton), 2016-12, Vol.55 (48), p.6599-6604

2016

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Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase

Biochemistry (Easton), 2016-05, Vol.55 (20), p.2864-2874

2016

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Incubation of 2-methylisoborneol synthase with the intermediate analog 2-methylneryl diphosphate

Journal of antibiotics, 2017-05, Vol.70 (5), p.625-631

2017

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The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation

Molecular biology of the cell, 2011-10, Vol.22 (20), p.3791-3800

2011

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Unexpected Reactivity of 2‑Fluorolinalyl Diphosphate in the Active Site of Crystalline 2‑Methylisoborneol Synthase

Biochemistry (Easton), 2013-08, Vol.52 (31), p.5247-5255

2013

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Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with Alpha-Alpha Domain Architecture that Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence

Biochemistry (Easton), 2015-12, Vol.54 (48), p.7142-7155

2015

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ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells

Molecular cancer, 2008-11, Vol.7 (1), p.87-87

2008

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Erinacine A-Enriched Hericium erinaceus Mycelium Delays Progression of Age-Related Cognitive Decline in Senescence Accelerated Mouse Prone 8 (SAMP8) Mice

Nutrients, 2021-10, Vol.13 (10), p.3659

2021

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RNA virus hijacks an incognito function of a DNA repair enzyme

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (36), p.14634-14639

2012

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An Overview of the Vaccinia Virus Infectome: a Survey of the Proteins of the Poxvirus-Infected Cell

Journal of Virology, 2012-02, Vol.86 (3), p.1487-1499

2012

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Analysis of stromal cell secretomes reveals a critical role for stromal cell-derived hepatocyte growth factor and fibronectin in angiogenesis

Arteriosclerosis, thrombosis, and vascular biology, 2013-03, Vol.33 (3), p.513

2013

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Picornavirus modification of a host mRNA decay protein

mBio, 2012-11, Vol.3 (6), p.e00431-e00412

2012

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Identification and Characterization of NeuB3 from Campylobacter jejuni as a Pseudaminic Acid Synthase

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.35922-35928

2005

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6″-Azido-6″-deoxy-UDP- N-acetylglucosamine as a glycosyltransferase substrate

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (4), p.1199-1201

2011

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"TOF2H": a precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI approach, covering the data pipeline from spectral acquisition to HDX rate analysis

BMC bioinformatics, 2008-09, Vol.9 (1), p.387-387, Article 387

2008

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An unusual case of sarcomatoid alk negative anaplastic large cell lymphoma

Pathology, 2018-02, Vol.50, p.S72-S72

2018

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Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases

Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase

Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes

Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization–Fragmentation Reaction Sequence

Structure of 2-Methylisoborneol Synthase from Streptomyces coelicolor and Implications for the Cyclization of a Noncanonical C-Methylated Monoterpenoid Substrate

Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi-Isozizaene Synthase

Genome Mining in Streptomyces avermitilis: Cloning and Characterization of SAV_76, the Synthase for a New Sesquiterpene, Avermitilol

Structure of Geranyl Diphosphate C-Methyltransferase from Streptomyces coelicolor and Implications for the Mechanism of Isoprenoid Modification

Cloning and characterization of Pfl_1841, a 2-methylenebornane synthase in Pseudomonas fluorescens PfO-1

The T296V Mutant of Amorpha-4,11-diene Synthase Is Defective in Allylic Diphosphate Isomerization but Retains the Ability To Cyclize the Intermediate (3R)‑Nerolidyl Diphosphate to Amorpha-4,11-diene

Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase

Incubation of 2-methylisoborneol synthase with the intermediate analog 2-methylneryl diphosphate

The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation

Unexpected Reactivity of 2‑Fluorolinalyl Diphosphate in the Active Site of Crystalline 2‑Methylisoborneol Synthase

Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with Alpha-Alpha Domain Architecture that Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence

ALDH isozymes downregulation affects cell growth, cell motility and gene expression in lung cancer cells

Erinacine A-Enriched Hericium erinaceus Mycelium Delays Progression of Age-Related Cognitive Decline in Senescence Accelerated Mouse Prone 8 (SAMP8) Mice

RNA virus hijacks an incognito function of a DNA repair enzyme

An Overview of the Vaccinia Virus Infectome: a Survey of the Proteins of the Poxvirus-Infected Cell

Analysis of stromal cell secretomes reveals a critical role for stromal cell-derived hepatocyte growth factor and fibronectin in angiogenesis

Picornavirus modification of a host mRNA decay protein

Identification and Characterization of NeuB3 from Campylobacter jejuni as a Pseudaminic Acid Synthase

6″-Azido-6″-deoxy-UDP- N-acetylglucosamine as a glycosyltransferase substrate

"TOF2H": a precision toolbox for rapid, high density/high coverage hydrogen-deuterium exchange mass spectrometry via an LC-MALDI approach, covering the data pipeline from spectral acquisition to HDX rate analysis

An unusual case of sarcomatoid alk negative anaplastic large cell lymphoma

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