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Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

Pharmacological reviews, 2006-09, Vol.58 (3), p.621-681

Chou, Ting-Chao

2006

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Drug combination studies and their synergy quantification using the Chou-Talalay method

Cancer research (Chicago, Ill.), 2010-01, Vol.70 (2), p.440-446

Chou, Ting-Chao

2010

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Significantly enhanced coupling effect and gap plasmon resonance in a MIM-cavity based sensing structure

Scientific reports, 2021-09, Vol.11 (1), p.18515-18515, Article 18515

2021

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Therapeutic inhibition of polo‐like kinases in anaplastic thyroid cancer

Cancer science, 2021-02, Vol.112 (2), p.803-814

2021

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The Use of Gigantochloa Bamboo-Derived Biochar for the Removal of Methylene Blue from Aqueous Solution

Adsorption science & technology, 2022, Vol.2022

2022

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Breaking the Symmetry of a Metal–Insulator–Metal-Based Resonator for Sensing Applications

Nanoscale research letters, 2022-04, Vol.17 (1), p.48-14, Article 48

2022

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Co-exposure to low doses of the food contaminants deoxynivalenol and nivalenol has a synergistic inflammatory effect on intestinal explants

Archives of toxicology, 2017-07, Vol.91 (7), p.2677-2687

2017

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Multiple Fano resonance modes in an ultra-compact plasmonic waveguide-cavity system for sensing applications

Results in physics, 2021-08, Vol.27, p.104527, Article 104527

2021

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Manipulating near field enhancement and optical spectrum in a pair-array of the cavity resonance based plasmonic nanoantennas

Journal of physics. D, Applied physics, 2016-11, Vol.49 (47), p.475102

2016

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Ultrawide Bandgap and High Sensitivity of a Plasmonic Metal-Insulator-Metal Waveguide Filter with Cavity and Baffles

Nanomaterials (Basel, Switzerland), 2020-10, Vol.10 (10), p.2030

2020

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Ultra-broad bandgap metal-insulator-metal waveguide filter with symmetrical stubs and defects

Results in physics, 2020-06, Vol.17, p.103116, Article 103116

2020

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Visible-Range Multiple-Channel Metal-Shell Rod-Shaped Narrowband Plasmonic Metamaterial Absorber for Refractive Index and Temperature Sensing

Micromachines (Basel), 2023-01, Vol.14 (2), p.340

2023

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Ultra-High Refractive Index Sensing Structure Based on a Metal-Insulator-Metal Waveguide-Coupled T-Shape Cavity with Metal Nanorod Defects

Nanomaterials (Basel, Switzerland), 2019-10, Vol.9 (10), p.1433

2019

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Susceptible Plasmonic Photonic Crystal Fiber Sensor with Elliptical Air Holes and External-Flat Gold-Coated Surface

Photonics, 2022-12, Vol.9 (12), p.916

2022

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Highly Sensitive and Tunable Plasmonic Sensor Based on a Nanoring Resonator with Silver Nanorods

Nanomaterials (Basel, Switzerland), 2020-07, Vol.10 (7), p.1399

2020

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Highly Sensitive Multichannel Fano Resonance-Based Plasmonic Sensor for Refractive Index and Temperature Sensing Application

Photonics, 2023-01, Vol.10 (1), p.82

2023

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A multichannel color filter with the functions of optical sensor and switch

Scientific reports, 2021-11, Vol.11 (1), p.22910-22910, Article 22910

2021

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Plasmonic perfect absorber based on metal nanorod arrays connected with veins

Results in physics, 2019-12, Vol.15, p.102567, Article 102567

2019

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Perfect Dual-Band Absorber Based on Plasmonic Effect with the Cross-Hair/Nanorod Combination

Nanomaterials (Basel, Switzerland), 2020-03, Vol.10 (3), p.493

2020

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High Sensitivity of Metasurface-Based Five-Band Terahertz Absorber

Plasmonics (Norwell, Mass.), 2024-02, Vol.19 (1), p.481-493

2024

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A cyclin-dependent kinase inhibitor, dinaciclib in preclinical treatment models of thyroid cancer

PloS one, 2017-02, Vol.12 (2), p.e0172315-e0172315

2017

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Near- and Mid- Infrared Quintuple-Band Plasmonic Metamaterial Absorber

Plasmonics (Norwell, Mass.), 2023-08, Vol.18 (4), p.1581-1591

2023

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Mathematical definitions of “additive effect of two (or more) drugs” and their synergism and/or antagonism based on mass‐action law (MAL) algorithms for pharmacodynamics (PD), biodynamics (BD) and bioinformatics (BI) simulations

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

Chou, Ting‐Chao

2022

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Functional biodynamics theory and algorithms for inhibitor or activator effectors and their interactions, by computer simulation bioinformatics for translational medicine

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

Chou, Ting‐Chao

2022

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MAL‐pharmacodynamics theory based small‐size experimental‐design and analysis, in vitro, in animals and in clinical trial, with bioinformatics algorithm, for automated computer simulation to achieve quantitative/digital/indexed conclusions

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

Chou, Ting‐Chao

2022

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Theoretical basis, experimental design, and computerized simulation of synergism and antagonism in drug combination studies

Drug combination studies and their synergy quantification using the Chou-Talalay method

Significantly enhanced coupling effect and gap plasmon resonance in a MIM-cavity based sensing structure

Therapeutic inhibition of polo‐like kinases in anaplastic thyroid cancer

The Use of Gigantochloa Bamboo-Derived Biochar for the Removal of Methylene Blue from Aqueous Solution

Breaking the Symmetry of a Metal–Insulator–Metal-Based Resonator for Sensing Applications

Co-exposure to low doses of the food contaminants deoxynivalenol and nivalenol has a synergistic inflammatory effect on intestinal explants

Multiple Fano resonance modes in an ultra-compact plasmonic waveguide-cavity system for sensing applications

Manipulating near field enhancement and optical spectrum in a pair-array of the cavity resonance based plasmonic nanoantennas

Ultrawide Bandgap and High Sensitivity of a Plasmonic Metal-Insulator-Metal Waveguide Filter with Cavity and Baffles

Ultra-broad bandgap metal-insulator-metal waveguide filter with symmetrical stubs and defects

Visible-Range Multiple-Channel Metal-Shell Rod-Shaped Narrowband Plasmonic Metamaterial Absorber for Refractive Index and Temperature Sensing

Ultra-High Refractive Index Sensing Structure Based on a Metal-Insulator-Metal Waveguide-Coupled T-Shape Cavity with Metal Nanorod Defects

Susceptible Plasmonic Photonic Crystal Fiber Sensor with Elliptical Air Holes and External-Flat Gold-Coated Surface

Highly Sensitive and Tunable Plasmonic Sensor Based on a Nanoring Resonator with Silver Nanorods

Highly Sensitive Multichannel Fano Resonance-Based Plasmonic Sensor for Refractive Index and Temperature Sensing Application

A multichannel color filter with the functions of optical sensor and switch

Plasmonic perfect absorber based on metal nanorod arrays connected with veins

Perfect Dual-Band Absorber Based on Plasmonic Effect with the Cross-Hair/Nanorod Combination

High Sensitivity of Metasurface-Based Five-Band Terahertz Absorber

A cyclin-dependent kinase inhibitor, dinaciclib in preclinical treatment models of thyroid cancer

Near- and Mid- Infrared Quintuple-Band Plasmonic Metamaterial Absorber

Mathematical definitions of “additive effect of two (or more) drugs” and their synergism and/or antagonism based on mass‐action law (MAL) algorithms for pharmacodynamics (PD), biodynamics (BD) and bioinformatics (BI) simulations

Functional biodynamics theory and algorithms for inhibitor or activator effectors and their interactions, by computer simulation bioinformatics for translational medicine

MAL‐pharmacodynamics theory based small‐size experimental‐design and analysis, in vitro, in animals and in clinical trial, with bioinformatics algorithm, for automated computer simulation to achieve quantitative/digital/indexed conclusions

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