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Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis

Toxicological sciences, 2016-04, Vol.150 (2), p.261-268

2016

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Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

Regulatory toxicology and pharmacology, 2017-12, Vol.91 (Suppl 1), p.S3-S13

2017

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Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor

PloS one, 2018-08, Vol.13 (8), p.e0200004

2018

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MicroRNA Biomarkers of Toxicity in Biological Matrices

Toxicological sciences, 2016-08, Vol.152 (2), p.264-272

2016

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Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid

Frontiers in oncology, 2024-05, Vol.14, p.1389634-1389634

2024

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Epigenetic Applications in Adverse Outcome Pathways and Environmental Risk Evaluation

Environmental health perspectives, 2018-04, Vol.126 (4), p.045001

2018

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Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice

Toxicology (Amsterdam), 2020-04, Vol.435, p.152409-152409, Article 152409

2020

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Enhanced Quality Metrics for Assessing RNA Derived From Archival Formalin-Fixed Paraffin-Embedded Tissue Samples

Toxicological sciences, 2019-08, Vol.170 (2), p.357-373

2019

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A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders

Cell reports (Cambridge), 2016-04, Vol.15 (4), p.830-842

2016

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A generic Transcriptomics Reporting Framework (TRF) for ‘omics data processing and analysis

Regulatory toxicology and pharmacology, 2017-12, Vol.91 (Suppl 1), p.S36-S45

2017

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Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer

PloS one, 2010-08, Vol.5 (8), p.e11934

2010

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Framework for the quality assurance of ’omics technologies considering GLP requirements

Regulatory toxicology and pharmacology, 2017-12, Vol.91 (Suppl 1), p.S27-S35

2017

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Novel Hematopoietic Target Genes in the NRF2-Mediated Transcriptional Pathway

Oxidative medicine and cellular longevity, 2013-01, Vol.2013, p.120305-12

2013

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Identification of polymorphic antioxidant response elements in the human genome

Human molecular genetics, 2007-05, Vol.16 (10), p.1188-1200

2007

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Developing a Gene Biomarker at the Tipping Point of Adaptive and Adverse Responses in Human Bronchial Epithelial Cells

PloS one, 2016-05, Vol.11 (5), p.e0155875

2016

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Early microRNA indicators of PPARα pathway activation in the liver

Toxicology reports, 2020-01, Vol.7, p.805-815

2020

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Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha

Nucleic acids research, 2012-08, Vol.40 (15), p.7416

2012

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Ozone-induced fetal growth restriction in rats is associated with sexually dimorphic placental and fetal metabolic adaptation

Molecular metabolism (Germany), 2020-12, Vol.42, p.101094, Article 101094

2020

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Editor's Highlight: Dose-Response Analysis of RNA-Seq Profiles in Archival Formalin-Fixed Paraffin-Embedded Samples

Toxicological sciences, 2016-12, Vol.154 (2), p.202-213

2016

Volltextzugriff (PDF)

Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology

Regulatory toxicology and pharmacology, 2021-10, Vol.125, p.105020-105020, Article 105020

2021

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Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts

PLoS genetics, 2009-05, Vol.5 (5), p.e1000462-e1000462

2009

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Circulating MicroRNAs, Polychlorinated Biphenyls, and Environmental Liver Disease in the Anniston Community Health Survey

Environmental health perspectives, 2022-01, Vol.130 (1), p.17003

2022

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Vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction

Toxicological sciences, 2023-05, Vol.193 (1), p.103-114

2023

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Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron

Toxicological sciences, 2021-02, Vol.180 (1), p.1-16

2021

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Early microRNA responses in rodent liver mediated by furan exposure establish dose thresholds for later adverse outcomes

Toxicology letters, 2023-08, Vol.384, p.105-114

2023

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Tipping the Balance: Hepatotoxicity and the 4 Apical Key Events of Hepatic Steatosis

Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop

Activation of Nrf2 in the liver is associated with stress resistance mediated by suppression of the growth hormone-regulated STAT5b transcription factor

MicroRNA Biomarkers of Toxicity in Biological Matrices

Persistent gene expression and DNA methylation alterations linked to carcinogenic effects of dichloroacetic acid

Epigenetic Applications in Adverse Outcome Pathways and Environmental Risk Evaluation

Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice

Enhanced Quality Metrics for Assessing RNA Derived From Archival Formalin-Fixed Paraffin-Embedded Tissue Samples

A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders

A generic Transcriptomics Reporting Framework (TRF) for ‘omics data processing and analysis

Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer

Framework for the quality assurance of ’omics technologies considering GLP requirements

Novel Hematopoietic Target Genes in the NRF2-Mediated Transcriptional Pathway

Identification of polymorphic antioxidant response elements in the human genome

Developing a Gene Biomarker at the Tipping Point of Adaptive and Adverse Responses in Human Bronchial Epithelial Cells

Early microRNA indicators of PPARα pathway activation in the liver

Identification of novel NRF2-regulated genes by ChIP-Seq: influence on retinoid X receptor alpha

Ozone-induced fetal growth restriction in rats is associated with sexually dimorphic placental and fetal metabolic adaptation

Editor's Highlight: Dose-Response Analysis of RNA-Seq Profiles in Archival Formalin-Fixed Paraffin-Embedded Samples

Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology

Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts

Circulating MicroRNAs, Polychlorinated Biphenyls, and Environmental Liver Disease in the Anniston Community Health Survey

Vinyl chloride enhances high-fat diet-induced proteome alterations in the mouse pancreas related to metabolic dysfunction

Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron

Early microRNA responses in rodent liver mediated by furan exposure establish dose thresholds for later adverse outcomes

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