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Synthesis of phenanthridine spiropyrans and studies of their effects on G-quadruplex DNA

Organic & biomolecular chemistry, 2017, Vol.15 (15), p.3265-3275

2017

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Glucocorticoid receptor gene expression in adipose tissue and associated metabolic risk in black and white South African women

International Journal of Obesity, 2015-02, Vol.39 (2), p.303-311

2015

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Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication

Nucleic acids research, 2020-11, Vol.48 (19), p.10998

2020

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The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation

Molecular cell, 2015-02, Vol.57 (3), p.445-455

2015

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Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity

Diabetologia, 2021-07, Vol.64 (7), p.1642-1659

2021

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Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner

Scientific reports, 2015-07, Vol.5 (1), p.12531-12531, Article 12531

2015

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Insulin-degrading enzyme is activated by the C-terminus of α-synuclein

Biochemical and biophysical research communications, 2015-10, Vol.466 (2), p.192-195

2015

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Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes

Diabetologia, 2021-09, Vol.64 (9), p.2077-2091

2021

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Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts

PloS one, 2015, Vol.10 (10), p.e0140194-e0140194

2015

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G4-Ligand-Conjugated Oligonucleotides Mediate Selective Binding and Stabilization of Individual G4 DNA Structures

Journal of the American Chemical Society, 2024-03, Vol.146 (10), p.6926-6935

2024

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Postprandial levels of GLP-1, GIP and glucagon after 2 years of weight loss with a Paleolithic diet: a randomised controlled trial in healthy obese women

European journal of endocrinology, 2019-06, Vol.180 (6), p.417

2019

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Pregnancy to postpartum transition of serum metabolites in women with gestational diabetes

Metabolism, clinical and experimental, 2017-07, Vol.72, p.27-36

2017

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Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson's disease

PloS one, 2017-09, Vol.12 (9), p.e0184117

2017

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Metabolic Profiling of Plasma in Patients with Irritable Bowel Syndrome after a 4-Week Starch- and Sucrose-Reduced Diet

Metabolites, 2021, Vol.11 (7), p.440

2021

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Synthesis of Multiring Fused 2‑Pyridones via a Nitrene Insertion Reaction: Fluorescent Modulators of α‑Synuclein Amyloid Formation

Organic letters, 2015-12, Vol.17 (24), p.6194-6197

2015

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Attenuated Low‐Grade Inflammation Following Long‐Term Dietary Intervention in Postmenopausal Women with Obesity

Obesity (Silver Spring, Md.), 2017-05, Vol.25 (5), p.892-900

2017

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The liver-alpha-cell axis during weight loss in type 2 diabetes

Diabetologia, 2018, Vol.61, p.S97

2018

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Synthesis of phenanthridine spiropyrans and studies of their effects on G-quadruplex DNAElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ob00300e

2017-04

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Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA

Cell chemical biology, 2016-03, Vol.23 (3), p.404-414

2016

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Plasma metabolomic response to postmenopausal weight loss induced by different diets

Metabolomics, 2016-05, Vol.12 (5), p.1, Article 85

2016

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Single injection of small-molecule amyloid accelerator results in cell death of nigral dopamine neurons in mice

NPJ Parkinson's Disease, 2015-01, Vol.1 (1), p.15024-15024, Article 15024

2015

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Microwave-assisted decarboxylation of bicyclic 2-pyridone scaffolds and identification of Aβ-peptide aggregation inhibitors

Organic & biomolecular chemistry, 2005-01, Vol.3 (15), p.2817

2005

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The effect of side chain variations on quinazoline-pyrimidine G-quadruplex DNA ligands

European journal of medicinal chemistry, 2023-02, Vol.248, p.115103, Article 115103

2023

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Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli

mBio, 2014-10, Vol.5 (6), p.e02038

2014

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Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G‑Quadruplex Stabilization

Journal of the American Chemical Society, 2020-02, Vol.142 (6), p.2876-2888

2020

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Synthesis of phenanthridine spiropyrans and studies of their effects on G-quadruplex DNA

Glucocorticoid receptor gene expression in adipose tissue and associated metabolic risk in black and white South African women

Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication

The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation

Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity

Insulin-degrading enzyme prevents α-synuclein fibril formation in a nonproteolytical manner

Insulin-degrading enzyme is activated by the C-terminus of α-synuclein

Branched-chain amino acid metabolism is regulated by ERRα in primary human myotubes and is further impaired by glucose loading in type 2 diabetes

Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts

G4-Ligand-Conjugated Oligonucleotides Mediate Selective Binding and Stabilization of Individual G4 DNA Structures

Postprandial levels of GLP-1, GIP and glucagon after 2 years of weight loss with a Paleolithic diet: a randomised controlled trial in healthy obese women

Pregnancy to postpartum transition of serum metabolites in women with gestational diabetes

Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson's disease

Metabolic Profiling of Plasma in Patients with Irritable Bowel Syndrome after a 4-Week Starch- and Sucrose-Reduced Diet

Synthesis of Multiring Fused 2‑Pyridones via a Nitrene Insertion Reaction: Fluorescent Modulators of α‑Synuclein Amyloid Formation

Attenuated Low‐Grade Inflammation Following Long‐Term Dietary Intervention in Postmenopausal Women with Obesity

The liver-alpha-cell axis during weight loss in type 2 diabetes

Synthesis of phenanthridine spiropyrans and studies of their effects on G-quadruplex DNAElectronic supplementary information (ESI) available. See DOI: 10.1039/c7ob00300e

Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA

Plasma metabolomic response to postmenopausal weight loss induced by different diets

Single injection of small-molecule amyloid accelerator results in cell death of nigral dopamine neurons in mice

Microwave-assisted decarboxylation of bicyclic 2-pyridone scaffolds and identification of Aβ-peptide aggregation inhibitors

The effect of side chain variations on quinazoline-pyrimidine G-quadruplex DNA ligands

Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli

Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G‑Quadruplex Stabilization

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