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The discovery of the Factor Xa inhibitor otamixaban: from lead identification to clinical development

Current medicinal chemistry, 2007-10, Vol.14 (23), p.2471-2481

2007

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Structure and Dynamics of Human Perilipin 3 Membrane Association

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Measurement of neutral ceramidase activity in vitro and in vivo

Analytical biochemistry, 2022-04, Vol.643, p.114577-114577, Article 114577

2022

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Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed

PloS one, 2016-12, Vol.11 (12), p.e0168019

2016

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Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation

Nature communications, 2023-06, Vol.14 (1), p.3204-16, Article 3204

2023

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The middle lipin domain adopts a membrane-binding dimeric protein fold

Nature communications, 2021-08, Vol.12 (1), p.4718-14, Article 4718

2021

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Enantiomeric characterization and structure elucidation of Otamixaban

Journal of pharmaceutical analysis, 2014-06, Vol.4 (3), p.197-204

2014

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Neutral ceramidase-active site inhibitor chemotypes and binding modes

Bioorganic chemistry, 2023-10, Vol.139, p.106747-106747, Article 106747

2023

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Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening

SLAS discovery, 2021-01, Vol.26 (1), p.113-121

2021

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Inhibitory Effects of Flavonoids on Growth of HT-29 Human Colon Cancer Cells

Han'guk Sikp'um Yŏngyang Kwahakhoe chi, 2015, Vol.44 (3), p.338-346

2015

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X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase

Bioorganic & medicinal chemistry letters, 2012-05, Vol.22 (9), p.3296-3300

2012

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Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening

Bioorganic & medicinal chemistry letters, 2009-12, Vol.19 (23), p.6717-6720

2009

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Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site

Bioorganic & medicinal chemistry letters, 2010-03, Vol.20 (6), p.1821-1824

2010

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In Vitro Characterization of a Novel Factor Xa Inhibitor, RPR 130737

Thrombosis research, 2000-07, Vol.99 (1), p.71-82

2000

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Biochemical and Structural Study of Perilipins and HSL That Govern the Cellular Lipolysis on LDs

Choi, Yong-Mi

2023

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Abstract CT512: A technology-based intervention using computers and mobile devices: To improve symptom experience of Asian American breast cancer survivors

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.CT512-CT512

2022

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New synthesis of 2-azetines and 1-azabutadienes and the use of the latter in Diels-Alder reactions: total synthesis of (.+-.)-.delta.-coniceine

Journal of organic chemistry, 1991-11, Vol.56 (24), p.6729-6730

1991

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Discovery of the first selective, small-molecule GFRα2/3 inhibitors through DNA-encoded library technology

Bioorganic & medicinal chemistry letters, 2024-09, Vol.110, p.129889, Article 129889

2024

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Design and Structure−Activity Relationships of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

Journal of medicinal chemistry, 1999-09, Vol.42 (18), p.3557-3571

1999

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Brain Penetrable Inhibitors of Ceramide Galactosyltransferase for the Treatment of Lysosomal Storage Disorders

ACS medicinal chemistry letters, 2020-10, Vol.11 (10), p.2010-2016

2020

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Groundwater contamination and natural attenuation capacity at a petroleum spilled facility in Korea

Journal of environmental sciences (China), 2011-01, Vol.23 (10), p.1650-1659

2011

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Synthesis of allenes via thermal cycloreversion of .alpha.-alkylidene-.beta.-lactones

Journal of organic chemistry, 1993-01, Vol.58 (2), p.322-327

1993

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Molecular Structures of Human Factor Xa Complexed with Ketopiperazine Inhibitors: Preference for a Neutral Group in the S1 Pocket

Journal of medicinal chemistry, 2003-02, Vol.46 (5), p.685-690

2003

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A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity

Bioorganic & medicinal chemistry letters, 2012-02, Vol.22 (4), p.1606-1610

2012

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Anionic- and Lipophilic-Mediated Surface Binding Inhibitors of Human Leukocyte Elastase

Journal of medicinal chemistry, 1997-10, Vol.40 (21), p.3408-3422

1997

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The discovery of the Factor Xa inhibitor otamixaban: from lead identification to clinical development

Structure and Dynamics of Human Perilipin 3 Membrane Association

Measurement of neutral ceramidase activity in vitro and in vivo

Structural Analysis of Thymidylate Synthase from Kaposi's Sarcoma-Associated Herpesvirus with the Anticancer Drug Raltitrexed

Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation

The middle lipin domain adopts a membrane-binding dimeric protein fold

Enantiomeric characterization and structure elucidation of Otamixaban

Neutral ceramidase-active site inhibitor chemotypes and binding modes

Identification of Small-Molecule Inhibitors of Neutral Ceramidase (nCDase) via Target-Based High-Throughput Screening

Inhibitory Effects of Flavonoids on Growth of HT-29 Human Colon Cancer Cells

X-ray crystallographic structure-based design of selective thienopyrazole inhibitors for interleukin-2-inducible tyrosine kinase

Discovery of covalent inhibitors for MIF tautomerase via cocrystal structures with phantom hits from virtual screening

Fragment screening of inhibitors for MIF tautomerase reveals a cryptic surface binding site

In Vitro Characterization of a Novel Factor Xa Inhibitor, RPR 130737

Biochemical and Structural Study of Perilipins and HSL That Govern the Cellular Lipolysis on LDs

Abstract CT512: A technology-based intervention using computers and mobile devices: To improve symptom experience of Asian American breast cancer survivors

New synthesis of 2-azetines and 1-azabutadienes and the use of the latter in Diels-Alder reactions: total synthesis of (.+-.)-.delta.-coniceine

Discovery of the first selective, small-molecule GFRα2/3 inhibitors through DNA-encoded library technology

Design and Structure−Activity Relationships of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

Brain Penetrable Inhibitors of Ceramide Galactosyltransferase for the Treatment of Lysosomal Storage Disorders

Groundwater contamination and natural attenuation capacity at a petroleum spilled facility in Korea

Synthesis of allenes via thermal cycloreversion of .alpha.-alkylidene-.beta.-lactones

Molecular Structures of Human Factor Xa Complexed with Ketopiperazine Inhibitors: Preference for a Neutral Group in the S1 Pocket

A β-tryptase inhibitor with a tropanylamide scaffold to improve in vitro stability and to lower hERG channel binding affinity

Anionic- and Lipophilic-Mediated Surface Binding Inhibitors of Human Leukocyte Elastase

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