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Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

Journal of hematology and oncology, 2013-02, Vol.6 (1), p.19-19, Article 19

2013

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Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm

Cardiovascular research, 2021-02, Vol.117 (3), p.971-982

2021

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Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway

Arteriosclerosis, thrombosis, and vascular biology, 2015-04, Vol.35 (4), p.804

2015

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Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism

Frontiers in immunology, 2021-06, Vol.12, p.653110-653110

2021

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Homocysteine-methionine cycle is a metabolic sensor system controlling methylation-regulated pathological signaling

Redox biology, 2020-01, Vol.28, p.101322-101322, Article 101322

2020

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Hyperhomocysteinemia potentiates hyperglycemia-induced inflammatory monocyte differentiation and atherosclerosis

Diabetes (New York, N.Y.), 2014-12, Vol.63 (12), p.4275-4290

2014

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MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity

Cell reports (Cambridge), 2013-12, Vol.5 (6), p.1576-1588

2013

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GATA3, HDAC6, and BCL6 Regulate FOXP3+ Treg Plasticity and Determine Treg Conversion into Either Novel Antigen-Presenting Cell-Like Treg or Th1-Treg

Frontiers in immunology, 2018-01, Vol.9, p.45

2018

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Interleukin-19 increases angiogenesis in ischemic hind limbs by direct effects on both endothelial cells and macrophage polarization

Journal of molecular and cellular cardiology, 2015-02, Vol.79, p.21-31

2015

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Novel extracellular and nuclear caspase-1 and inflammasomes propagate inflammation and regulate gene expression: a comprehensive database mining study

Journal of hematology and oncology, 2016-11, Vol.9 (1), p.122-122, Article 122

2016

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Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation

Redox biology, 2021-11, Vol.47, p.102142-102142, Article 102142

2021

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End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression

Redox biology, 2020-07, Vol.34, p.101460-101460, Article 101460

2020

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Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells - Novel qualification markers for chronic disease risk factors and conditional DAMPs

Redox biology, 2019-06, Vol.24, p.101221-101221, Article 101221

2019

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Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways

Frontiers in immunology, 2021-05, Vol.12, p.678201-678201

2021

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A Novel Subset of CD95 + Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy Obesity

Frontiers in immunology, 2021-01, Vol.11, p.619951-619951

2021

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Analyses of caspase-1-regulated transcriptomes in various tissues lead to identification of novel IL-1β-, IL-18- and sirtuin-1-independent pathways

Journal of hematology and oncology, 2017-02, Vol.10 (1), p.40-40, Article 40

2017

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Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors

Frontiers in immunology, 2019-11, Vol.10, p.2612-2612

2019

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Metabolism-associated danger signal-induced immune response and reverse immune checkpoint-activated CD40 + monocyte differentiation

Journal of hematology and oncology, 2017-07, Vol.10 (1), p.141-18, Article 141

2017

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In Vitro Study on Smart Stent for Autonomous Post-Endovascular Aneurysm Repair Surveillance

IEEE access, 2020, Vol.8, p.96340-96346

2020

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Experimental Data-Mining Analyses Reveal New Roles of Low-Intensity Ultrasound in Differentiating Cell Death Regulatome in Cancer and Non-cancer Cells via Potential Modulation of Chromatin Long-Range Interactions

Frontiers in oncology, 2019-07, Vol.9, p.600

2019

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Novel Knowledge-Based Transcriptomic Profiling of Lipid Lysophosphatidylinositol-Induced Endothelial Cell Activation

Frontiers in cardiovascular medicine, 2021-11, Vol.8, p.773473-773473

2021

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Mid-term outcomes of endovascular popliteal artery aneurysm repair

Journal of vascular surgery, 2007-03, Vol.45 (3), p.505-510

2007

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A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors

Journal of hematology and oncology, 2017-10, Vol.10 (1), p.168-168, Article 168

2017

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DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses-Inflammations and Cancers Can Have High Genomic Risks

Frontiers in physiology, 2018-05, Vol.9, p.516-516

2018

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Thrombus leukocytes exhibit more endothelial cell-specific angiogenic markers than peripheral blood leukocytes do in acute coronary syndrome patients, suggesting a possibility of trans-differentiation: a comprehensive database mining study

Journal of hematology and oncology, 2017-03, Vol.10 (1), p.74-74, Article 74

2017

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Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers

Targeting mitochondrial fission as a potential therapeutic for abdominal aortic aneurysm

Early hyperlipidemia promotes endothelial activation via a caspase-1-sirtuin 1 pathway

Endothelial Immunity Trained by Coronavirus Infections, DAMP Stimulations and Regulated by Anti-Oxidant NRF2 May Contribute to Inflammations, Myelopoiesis, COVID-19 Cytokine Storms and Thromboembolism

Homocysteine-methionine cycle is a metabolic sensor system controlling methylation-regulated pathological signaling

Hyperhomocysteinemia potentiates hyperglycemia-induced inflammatory monocyte differentiation and atherosclerosis

MICU1 Motifs Define Mitochondrial Calcium Uniporter Binding and Activity

GATA3, HDAC6, and BCL6 Regulate FOXP3+ Treg Plasticity and Determine Treg Conversion into Either Novel Antigen-Presenting Cell-Like Treg or Th1-Treg

Interleukin-19 increases angiogenesis in ischemic hind limbs by direct effects on both endothelial cells and macrophage polarization

Novel extracellular and nuclear caspase-1 and inflammasomes propagate inflammation and regulate gene expression: a comprehensive database mining study

Procaspase-1 patrolled to the nucleus of proatherogenic lipid LPC-activated human aortic endothelial cells induces ROS promoter CYP1B1 and strong inflammation

End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression

Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells - Novel qualification markers for chronic disease risk factors and conditional DAMPs

Canonical Secretomes, Innate Immune Caspase-1-, 4/11-Gasdermin D Non-Canonical Secretomes and Exosomes May Contribute to Maintain Treg-Ness for Treg Immunosuppression, Tissue Repair and Modulate Anti-Tumor Immunity via ROS Pathways

A Novel Subset of CD95 + Pro-Inflammatory Macrophages Overcome miR155 Deficiency and May Serve as a Switch From Metabolically Healthy Obesity to Metabolically Unhealthy Obesity

Analyses of caspase-1-regulated transcriptomes in various tissues lead to identification of novel IL-1β-, IL-18- and sirtuin-1-independent pathways

Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors

Metabolism-associated danger signal-induced immune response and reverse immune checkpoint-activated CD40 + monocyte differentiation

In Vitro Study on Smart Stent for Autonomous Post-Endovascular Aneurysm Repair Surveillance

Experimental Data-Mining Analyses Reveal New Roles of Low-Intensity Ultrasound in Differentiating Cell Death Regulatome in Cancer and Non-cancer Cells via Potential Modulation of Chromatin Long-Range Interactions

Novel Knowledge-Based Transcriptomic Profiling of Lipid Lysophosphatidylinositol-Induced Endothelial Cell Activation

Mid-term outcomes of endovascular popliteal artery aneurysm repair

A comprehensive data mining study shows that most nuclear receptors act as newly proposed homeostasis-associated molecular pattern receptors

DNA Checkpoint and Repair Factors Are Nuclear Sensors for Intracellular Organelle Stresses-Inflammations and Cancers Can Have High Genomic Risks

Thrombus leukocytes exhibit more endothelial cell-specific angiogenic markers than peripheral blood leukocytes do in acute coronary syndrome patients, suggesting a possibility of trans-differentiation: a comprehensive database mining study

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