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Patient-derived xenografts as compatible models for precision oncology

Laboratory Animal Research, 2020, 36(2), , pp.108-118

Cho, Sung-Yup

2020

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Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts

Nature communications, 2021-08, Vol.12 (1), p.4840-14, Article 4840

2021

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An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts

Molecules and Cells, 2016, 39(2), , pp.77-86

2016

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Genome‐scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib‐resistant lung cancer

Molecular oncology, 2021-02, Vol.15 (2), p.487-502

2021

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CRISPR screens identify a novel combination treatment targeting BCL-XL and WNT signaling for KRAS/BRAF-mutated colorectal cancers

Oncogene, 2021-05, Vol.40 (18), p.3287-3302

2021

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iCSDB: an integrated database of CRISPR screens

Nucleic acids research, 2021-01, Vol.49 (D1), p.D956

2021

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Real-Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function

Stem cell reports, 2018-02, Vol.10 (2), p.600-614

2018

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A Novel Combination Treatment Targeting BCL-XL and MCL1 for KRAS/BRAF -mutated and BCL2L1 -amplified Colorectal Cancers

Molecular cancer therapeutics, 2017-10, Vol.16 (10), p.2178-2190

2017

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Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2

eLife, 2021-07, Vol.10

2021

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Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers

Experimental and Molecular Medicine, 2020, 52(0), , pp.1-11

2020

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Augmentation of the RNA m6A reader signature is associated with poor survival by enhancing cell proliferation and EMT across cancer types

Experimental and Molecular Medicine, 2022, 54(0), , pp.1-16

2022

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Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (40), p.12492-12497

2015

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Transglutaminase 2 mediates transcriptional regulation through BAF250a polyamination

Genes & Genomics, 2021, 43(4), , pp.333-342

2021

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Transglutaminase 2 crosslinks the glutathione S-transferase tag, impeding protein-protein interactions of the fused protein

Experimental and Molecular Medicine, 2021, 53(0), , pp.1-10

2021

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Transglutaminase 2 Prevents Premature Senescence and Promotes Osteoblastic Differentiation of Mesenchymal Stem Cells through NRF2 Activation

Stem cells international, 2023-10, Vol.2023, p.1-16

2023

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Direct cell-to-cell transfer in stressed tumor microenvironment aggravates tumorigenic or metastatic potential in pancreatic cancer

Npj genomic medicine, 2022-10, Vol.7 (1), p.63-63, Article 63

2022

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Gut bacteria-derived 3-phenylpropionylglycine mitigates adipocyte differentiation of 3T3-L1 cells by inhibiting adiponectin-PPAR pathway

Genes & Genomics, 2023, 45(1), , pp.71-81

2023

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Transglutaminase 2 is dispensable but required for the survival of mice in dextran sulfate sodium-induced colitis

Experimental & molecular medicine, 2016-11, Vol.48 (11), p.e267-e267

2016

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Combined blockade of polo-like kinase and pan-RAF is effective against NRAS-mutant non-small cell lung cancer cells

Cancer letters, 2020-12, Vol.495 (C), p.135-144

2020

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Endoplasmic reticulum stress activates transglutaminase 2 leading to protein aggregation

International journal of molecular medicine, 2014-04, Vol.33 (4), p.849-855

2014

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Targeting antioxidant enzymes enhances the therapeutic efficacy of the BCL-XL inhibitor ABT-263 in KRAS-mutant colorectal cancers

Cancer letters, 2021-01, Vol.497 (C), p.123-136

2021

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Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability

Bioorganic & medicinal chemistry, 2024-02, Vol.100, p.117588-117588, Article 117588

2024

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Targeting the m6A RNA methyltransferase METTL3 attenuates the development of kidney fibrosis

Experimental & molecular medicine, 2024-02, Vol.56 (2), p.355-369

2024

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Unstable Genome and Transcriptome Dynamics during Tumor Metastasis Contribute to Therapeutic Heterogeneity in Colorectal Cancers

Clinical cancer research, 2019-05, Vol.25 (9), p.2821-2834

2019

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Patient-derived xenografts as compatible models for precision oncology

Predictive biomarkers for 5-fluorouracil and oxaliplatin-based chemotherapy in gastric cancers via profiling of patient-derived xenografts

An Integrative Approach to Precision Cancer Medicine Using Patient-Derived Xenografts

Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice

Genome‐scale CRISPR screening identifies cell cycle and protein ubiquitination processes as druggable targets for erlotinib‐resistant lung cancer

CRISPR screens identify a novel combination treatment targeting BCL-XL and WNT signaling for KRAS/BRAF-mutated colorectal cancers

iCSDB: an integrated database of CRISPR screens

Real-Time Monitoring of Glutathione in Living Cells Reveals that High Glutathione Levels Are Required to Maintain Stem Cell Function

A Novel Combination Treatment Targeting BCL-XL and MCL1 for KRAS/BRAF -mutated and BCL2L1 -amplified Colorectal Cancers

Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2

Amplification of transglutaminase 2 enhances tumor-promoting inflammation in gastric cancers

Augmentation of the RNA m6A reader signature is associated with poor survival by enhancing cell proliferation and EMT across cancer types

Genomic alterations in BCL2L1 and DLC1 contribute to drug sensitivity in gastric cancer

Transglutaminase 2 mediates transcriptional regulation through BAF250a polyamination

Transglutaminase 2 crosslinks the glutathione S-transferase tag, impeding protein-protein interactions of the fused protein

Transglutaminase 2 Prevents Premature Senescence and Promotes Osteoblastic Differentiation of Mesenchymal Stem Cells through NRF2 Activation

Direct cell-to-cell transfer in stressed tumor microenvironment aggravates tumorigenic or metastatic potential in pancreatic cancer

Gut bacteria-derived 3-phenylpropionylglycine mitigates adipocyte differentiation of 3T3-L1 cells by inhibiting adiponectin-PPAR pathway

Transglutaminase 2 is dispensable but required for the survival of mice in dextran sulfate sodium-induced colitis

Combined blockade of polo-like kinase and pan-RAF is effective against NRAS-mutant non-small cell lung cancer cells

Endoplasmic reticulum stress activates transglutaminase 2 leading to protein aggregation

Targeting antioxidant enzymes enhances the therapeutic efficacy of the BCL-XL inhibitor ABT-263 in KRAS-mutant colorectal cancers

Discovery of thiophen-2-ylmethylene bis-dimedone derivatives as novel WRN inhibitors for treating cancers with microsatellite instability

Targeting the m6A RNA methyltransferase METTL3 attenuates the development of kidney fibrosis

Unstable Genome and Transcriptome Dynamics during Tumor Metastasis Contribute to Therapeutic Heterogeneity in Colorectal Cancers

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