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Formation of reactive metabolites of benzbromarone in humanized-liver mice

Drug metabolism and pharmacokinetics, 2022-12, Vol.47, p.100467, Article 100467

2022

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Identification of novel glutathione adducts of benzbromarone in human liver microsomes

Drug metabolism and pharmacokinetics, 2017-02, Vol.32 (1), p.46-52

2017

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Safety, Tolerability, and Pharmacokinetics of a Novel Oral Phosphodiesterase 4 Inhibitor, ME3183: First‐in‐Human Phase 1 Study

Clinical pharmacology in drug development, 2024-04, Vol.13 (4), p.341-348

2024

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ME3183, a novel phosphodiesterase-4 inhibitor, exhibits potent anti-inflammatory effects and is well tolerated in a non-clinical study

European journal of pharmacology, 2024-01, Vol.962, p.176202-176202, Article 176202

2024

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Empirical and theoretical approaches for the prediction of human hepatic clearance using chimeric mice with humanised liver: the use of physiologically based scaling, a novel solution for potential overprediction due to coexisting mouse metabolism

Xenobiotica, 2021-09, Vol.51 (9), p.983-994

2021

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Selection of the candidate compound at an early stage of new drug development: retrospective pharmacokinetic and metabolic evaluations of valsartan using common marmosets

Xenobiotica, 2022-06, Vol.52 (6), p.613-624

2022

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Association of a reactive intermediate derived from 1′,6‐dihydroxy metabolite with benzbromarone‐induced hepatotoxicity

Journal of biochemical and molecular toxicology, 2017-10, Vol.31 (10), p.n/a

2017

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Mobile Context Awareness

1. Aufl., 2012

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Development of protein degradation inducers of oncogenic BCR‐ABL protein by conjugation of ABL kinase inhibitors and IAP ligands

Cancer science, 2017-08, Vol.108 (8), p.1657-1666

2017

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Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline

Nature communications, 2015-03, Vol.6 (1), p.6606, Article 6606

2015

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Molecular Mechanisms of Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury

International journal of molecular sciences, 2023-04, Vol.24 (9), p.7885

2023

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Development of a sea-ice tank system for measuring microwave properties of sea ice

Journal of glaciology, 2024-01, p.1-10

2024

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Development of a simultaneous partial nitrification and anaerobic ammonia oxidation process in a single reactor

Bioresource technology, 2011, Vol.102 (2), p.652-659

2011

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Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis

eLife, 2015-06, Vol.4

2015

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Overexpression of miR-142-5p and miR-155 in gastric mucosa-associated lymphoid tissue (MALT) lymphoma resistant to Helicobacter pylori eradication

PloS one, 2012-11, Vol.7 (11), p.e47396

2012

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Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target

Nature communications, 2022-10, Vol.13 (1), p.5974-5974, Article 5974

2022

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The Relationship Between Microwave Brightness Temperature, Salinity, and Thickness of Sea Ice Acquired With a Tank Experiment

IEEE transactions on geoscience and remote sensing, 2024, Vol.62, p.1-9

2024

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Effect of Grain Refinement on Room Temperature Ductility of Ferritic Heat-resistant Alloys Strengthened by NiAl Precipitates

ISIJ International, 2020/10/15, Vol.60(10), pp.2285-2290

2020

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Nitrogen removal performance and microbial community analysis of an anaerobic up-flow granular bed anammox reactor

Chemosphere (Oxford), 2010-02, Vol.78 (9), p.1129-1135

2010

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Occurrence of Haemophilus influenzae type b (Hib) meningitis in a 2 month-old infant in the Hib vaccination era

Journal of microbiology, immunology and infection, 2022-06, Vol.55 (3), p.554-555

2022

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Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation

ACS medicinal chemistry letters, 2017-10, Vol.8 (10), p.1042-1047

2017

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Sexual Dimorphism of Spinal Neural Circuits Controlling the Mouse External Urethral Sphincter With and Without Spinal Cord Injury

Journal of comparative neurology (1911), 2024-07, Vol.532 (7), p.e25658-n/a

2024

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Impact of different bilateral knee extension strengths on lower extremity performance

Medicine (Baltimore), 2021-09, Vol.100 (38), p.e27297-e27297

2021

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In Situ Formation of Protective Coatings on Sulfur Cathodes in Lithium Batteries with LiFSI-Based Organic Electrolytes

Advanced energy materials, 2015-03, Vol.5 (6), p.np-n/a

2015

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Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease

International journal of epidemiology, 2022-01, Vol.50 (6), p.1995-2010

2022

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Formation of reactive metabolites of benzbromarone in humanized-liver mice

Identification of novel glutathione adducts of benzbromarone in human liver microsomes

Safety, Tolerability, and Pharmacokinetics of a Novel Oral Phosphodiesterase 4 Inhibitor, ME3183: First‐in‐Human Phase 1 Study

ME3183, a novel phosphodiesterase-4 inhibitor, exhibits potent anti-inflammatory effects and is well tolerated in a non-clinical study

Empirical and theoretical approaches for the prediction of human hepatic clearance using chimeric mice with humanised liver: the use of physiologically based scaling, a novel solution for potential overprediction due to coexisting mouse metabolism

Selection of the candidate compound at an early stage of new drug development: retrospective pharmacokinetic and metabolic evaluations of valsartan using common marmosets

Association of a reactive intermediate derived from 1′,6‐dihydroxy metabolite with benzbromarone‐induced hepatotoxicity

Mobile Context Awareness

Development of protein degradation inducers of oncogenic BCR‐ABL protein by conjugation of ABL kinase inhibitors and IAP ligands

Aberrant hippocampal neurogenesis contributes to epilepsy and associated cognitive decline

Molecular Mechanisms of Neurogenic Lower Urinary Tract Dysfunction after Spinal Cord Injury

Development of a sea-ice tank system for measuring microwave properties of sea ice

Development of a simultaneous partial nitrification and anaerobic ammonia oxidation process in a single reactor

Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis

Overexpression of miR-142-5p and miR-155 in gastric mucosa-associated lymphoid tissue (MALT) lymphoma resistant to Helicobacter pylori eradication

Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target

The Relationship Between Microwave Brightness Temperature, Salinity, and Thickness of Sea Ice Acquired With a Tank Experiment

Effect of Grain Refinement on Room Temperature Ductility of Ferritic Heat-resistant Alloys Strengthened by NiAl Precipitates

Nitrogen removal performance and microbial community analysis of an anaerobic up-flow granular bed anammox reactor

Occurrence of Haemophilus influenzae type b (Hib) meningitis in a 2 month-old infant in the Hib vaccination era

Targeting the Allosteric Site of Oncoprotein BCR-ABL as an Alternative Strategy for Effective Target Protein Degradation

Sexual Dimorphism of Spinal Neural Circuits Controlling the Mouse External Urethral Sphincter With and Without Spinal Cord Injury

Impact of different bilateral knee extension strengths on lower extremity performance

In Situ Formation of Protective Coatings on Sulfur Cathodes in Lithium Batteries with LiFSI-Based Organic Electrolytes

Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease

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