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Chronic immune response dysregulation in MDS pathogenesis

Blood, 2018-10, Vol.132 (15), p.1553-1560

2018

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Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia

Cell stem cell, 2021-11, Vol.28 (11), p.1966-1981.e6

2021

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The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia

Leukemia, 2022-02, Vol.36 (2), p.438-451

2022

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Combinatorial regulation of tissue specification by GATA and FOG factors

Development (Cambridge), 2012-11, Vol.139 (21), p.3905-3916

2012

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Cofactor-Mediated Restriction of GATA-1 Chromatin Occupancy Coordinates Lineage-Specific Gene Expression

Molecular cell, 2012-08, Vol.47 (4), p.608-621

2012

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Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis

Blood, 2012-04, Vol.119 (16), p.3724-3733

2012

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Perturbation of fetal hematopoiesis in a mouse model of Down syndrome's transient myeloproliferative disorder

Blood, 2013-08, Vol.122 (6), p.988-998

2013

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Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage

Stem cell reports, 2016-01, Vol.6 (1), p.44-54

2016

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Germline DDX41 mutant predisposition syndromes: Slow driver states to hematological malignancies

American journal of hematology, 2023-11, Vol.98 (11), p.1673-1676

2023

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Global transcriptome and chromatin occupancy analysis reveal the short isoform of GATA1 is deficient for erythroid specification and gene expression

Haematologica (Roma), 2015-05, Vol.100 (5), p.575-584

2015

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Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin

Cell stem cell, 2021-03, Vol.28 (3), p.424-435.e6

2021

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Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

Blood, 2013-03, Vol.121 (13), p.2440-2451

2013

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High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells

Journal of virology, 2014-10, Vol.88 (19), p.11315-11326

2014

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Retinoids Modulate Expression of the Endocytic Partners Megalin, Cubilin, and Disabled-2 and Uptake of Vitamin D-Binding Protein in Human Mammary Cells

The Journal of nutrition, 2008-07, Vol.138 (7), p.1323-1328

2008

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Reduction in PU.1 activity results in a block to B-cell development, abnormal myeloid proliferation, and neonatal lethality

Experimental hematology, 2007-07, Vol.35 (7), p.1056-1068

2007

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The Inherited MDS Gene DDX41 Is Essential for Ribosomal RNA Processing through Regulation of Snorna Biogenesis

Blood, 2020-11, Vol.136 (Supplement 1), p.40-40

2020

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Heterozygous Mutations in DDX41 Cause Erythroid Progenitor Cell Defects

Blood, 2021-11, Vol.138 (Supplement 1), p.148-148

2021

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The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability

Blood, 2019-11, Vol.134 (Supplement_1), p.773-773

2019

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Stage Selective Requirement For The N-Terminus Of GATA1 During Erythropoiesis

Blood, 2013-11, Vol.122 (21), p.3670-3670

2013

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Identification of a GATA Switch In Megakaryocytic Development

Blood, 2010-11, Vol.116 (21), p.2605-2605

2010

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The Leukemic Isoform GATA-1s Is Deficient In Chromatin Occupancy: Implications for AMKL

Blood, 2010-11, Vol.116 (21), p.3643-3643

2010

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Inducible Loss of the Fanconi Anemia Pathway in iPSC Causes Rapid Cell Cycle Arrest and Apoptosis through ATM/ATR and p53 Signaling

Blood, 2014-12, Vol.124 (21), p.3528-3528

2014

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Gabp Transcription Factor Is Required for the Development of Mouse Megakaryocytes

Blood, 2010-11, Vol.116 (21), p.2604-2604

2010

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Development of Acute Megakaryoblastic Leukemia in Down Syndrome Is Associated with Sequential Epigenetic Changes That Target the Down Syndrome Critical Region on Chromosome 21

Blood, 2011-11, Vol.118 (21), p.3451-3451

2011

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Ikaros Is a GATA Switch Target Gene That Restrains Megakaryopoiesis In Part by Blocking Notch Signaling

Blood, 2010-11, Vol.116 (21), p.1602-1602

2010

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Chronic immune response dysregulation in MDS pathogenesis

Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia

The deubiquitinase USP15 modulates cellular redox and is a therapeutic target in acute myeloid leukemia

Combinatorial regulation of tissue specification by GATA and FOG factors

Cofactor-Mediated Restriction of GATA-1 Chromatin Occupancy Coordinates Lineage-Specific Gene Expression

Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis

Perturbation of fetal hematopoiesis in a mouse model of Down syndrome's transient myeloproliferative disorder

Overcoming Pluripotent Stem Cell Dependence on the Repair of Endogenous DNA Damage

Germline DDX41 mutant predisposition syndromes: Slow driver states to hematological malignancies

Global transcriptome and chromatin occupancy analysis reveal the short isoform of GATA1 is deficient for erythroid specification and gene expression

Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin

Ikaros inhibits megakaryopoiesis through functional interaction with GATA-1 and NOTCH signaling

High-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells

Retinoids Modulate Expression of the Endocytic Partners Megalin, Cubilin, and Disabled-2 and Uptake of Vitamin D-Binding Protein in Human Mammary Cells

Reduction in PU.1 activity results in a block to B-cell development, abnormal myeloid proliferation, and neonatal lethality

The Inherited MDS Gene DDX41 Is Essential for Ribosomal RNA Processing through Regulation of Snorna Biogenesis

Heterozygous Mutations in DDX41 Cause Erythroid Progenitor Cell Defects

The Inherited MDS Gene DDX41 Is Required for Ribosome Biogenesis and Cell Viability

Stage Selective Requirement For The N-Terminus Of GATA1 During Erythropoiesis

Identification of a GATA Switch In Megakaryocytic Development

The Leukemic Isoform GATA-1s Is Deficient In Chromatin Occupancy: Implications for AMKL

Inducible Loss of the Fanconi Anemia Pathway in iPSC Causes Rapid Cell Cycle Arrest and Apoptosis through ATM/ATR and p53 Signaling

Gabp Transcription Factor Is Required for the Development of Mouse Megakaryocytes

Development of Acute Megakaryoblastic Leukemia in Down Syndrome Is Associated with Sequential Epigenetic Changes That Target the Down Syndrome Critical Region on Chromosome 21

Ikaros Is a GATA Switch Target Gene That Restrains Megakaryopoiesis In Part by Blocking Notch Signaling

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