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Copper signaling axis as a target for prostate cancer therapeutics

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (20), p.5819-5831

2014

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Observations on the Effects of Residualization and Dehalogenation on the Utility of N -Succinimidyl Ester Acylation Agents for Radioiodination of the Internalizing Antibody Trastuzumab

Molecules (Basel, Switzerland), 2019-10, Vol.24 (21), p.3907

2019

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Efficient Synthesis and HPLC-Based Characterization for Developing Vanadium-48-Labeled Vanadyl Acetylacetonate as a Novel Cancer Radiotracer for PET Imaging

Molecules (Basel, Switzerland), 2024-02, Vol.29 (4), p.799

2024

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Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression

Cellular and molecular gastroenterology and hepatology, 2020-01, Vol.10 (1), p.1-21

2020

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Accelerator-Based Production of Scandium Radioisotopes for Applications in Prostate Cancer: Toward Building a Pipeline for Rapid Development of Novel Theranostics

Molecules (Basel, Switzerland), 2023-08, Vol.28 (16), p.6041

2023

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Feasibility of Developing Radiotracers for MDM2: Synthesis and Preliminary Evaluation of an 18F-Labeled Analogue of the MDM2 Inhibitor SP-141

Pharmaceuticals (Basel, Switzerland), 2021-04, Vol.14 (4), p.358

2021

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Stapled peptides as scaffolds for developing radiotracers for intracellular targets: Preliminary evaluation of a radioiodinated MDM2-binding stapled peptide in the SJSA-1 osteosarcoma model

Bioorganic & medicinal chemistry letters, 2022-06, Vol.66, p.128725-128725, Article 128725

2022

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Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation

Molecular pharmaceutics, 2021-10, Vol.18 (10), p.3871-3881

2021

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Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: Chemistry and preliminary evaluation

Bioorganic & medicinal chemistry, 2018-05, Vol.26 (8), p.1939-1949

2018

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Molecular imaging of hypoxia

Journal of Nuclear Medicine, 2011-02, Vol.52 (2), p.165-168

2011

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Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors

Bioorganic & medicinal chemistry letters, 2018-02, Vol.28 (4), p.694-699

2018

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A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma

Clinical cancer research, 2018-08, Vol.24 (15), p.3611-3631

2018

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Development and biological evaluation of 99mTc-sulfonamide derivatives for in vivo visualization of CA IX as surrogate tumor hypoxia markers

European journal of medicinal chemistry, 2014-01, Vol.71, p.374-384

2014

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Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: Synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs

European journal of medicinal chemistry, 2016-08, Vol.119, p.218-230

2016

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Synthesis and Evaluation of a 18 F-Labeled Triazinediamine Analogue for Imaging Mutant IDH1 Expression in Gliomas by PET

ACS medicinal chemistry letters, 2018-07, Vol.9 (7), p.606-611

2018

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Synthesis and Evaluation of a 18F‑Labeled Triazinediamine Analogue for Imaging Mutant IDH1 Expression in Gliomas by PET

ACS medicinal chemistry letters, 2018-07, Vol.9 (7), p.606-611

2018

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Comparison of the Hypoxia PET Tracer (18)F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models

The Journal of nuclear medicine (1978), 2014-07, Vol.55 (7), p.1192

2014

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Reply: Pharmacokinetic and Pharmacodynamic Modifiers of EF5 Uptake and Binding

Journal of Nuclear Medicine, 2015-04, Vol.56 (4), p.653-654

2015

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Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat model

American journal of obstetrics and gynecology, 2007-04, Vol.196 (4), p.352.e1-352.e6

2007

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A simplified synthesis of the hypoxia imaging agent 2-(2-Nitro-1 H -imidazol-1-yl)- N -(2,2,3,3,3-[18 F]pentafluoropropyl)-acetamide ([18 F]EF5)

Nuclear medicine and biology, 2012-10, Vol.39 (7), p.1012-1018

2012

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Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET

Nuclear medicine and biology, 2012-11, Vol.39 (8), p.1266-1274

2012

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18F-EF5 PET imaging as an early response biomarker for the hypoxia-activated prodrug SN30000 combined with radiation treatment in a non-small cell lung cancer xenograft model

The Journal of nuclear medicine (1978), 2013-08, Vol.54 (8), p.1339-1346

2013

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Necrosis avidity of (99m)Tc(CO)3-labeled pamoic acid derivatives: synthesis and preliminary biological evaluation in animal models of necrosis

Bioconjugate chemistry, 2007-11, Vol.18 (6), p.1924-1934

2007

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Efficient purification and metabolite analysis of radiotracers using high-performance liquid chromatography and on-line solid-phase extraction

Journal of Chromatography A, 2008-05, Vol.1189 (1), p.323-331

2008

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[18F]JNJ41510417 a potential PET radioligand for imaging phosphodiesterase-10A in the brain

NeuroImage (Orlando, Fla.), 2010-08, Vol.52 (S1), p.S15-S15

2010

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Copper signaling axis as a target for prostate cancer therapeutics

Observations on the Effects of Residualization and Dehalogenation on the Utility of N -Succinimidyl Ester Acylation Agents for Radioiodination of the Internalizing Antibody Trastuzumab

Efficient Synthesis and HPLC-Based Characterization for Developing Vanadium-48-Labeled Vanadyl Acetylacetonate as a Novel Cancer Radiotracer for PET Imaging

Increased Glutaminolysis Marks Active Scarring in Nonalcoholic Steatohepatitis Progression

Accelerator-Based Production of Scandium Radioisotopes for Applications in Prostate Cancer: Toward Building a Pipeline for Rapid Development of Novel Theranostics

Feasibility of Developing Radiotracers for MDM2: Synthesis and Preliminary Evaluation of an 18F-Labeled Analogue of the MDM2 Inhibitor SP-141

Stapled peptides as scaffolds for developing radiotracers for intracellular targets: Preliminary evaluation of a radioiodinated MDM2-binding stapled peptide in the SJSA-1 osteosarcoma model

Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation

Fluorine-18 labeling of an anti-HER2 VHH using a residualizing prosthetic group via a strain-promoted click reaction: Chemistry and preliminary evaluation

Molecular imaging of hypoxia

Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors

A Rationally Designed Fully Human EGFRvIII:CD3-Targeted Bispecific Antibody Redirects Human T Cells to Treat Patient-derived Intracerebral Malignant Glioma

Development and biological evaluation of 99mTc-sulfonamide derivatives for in vivo visualization of CA IX as surrogate tumor hypoxia markers

Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: Synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs

Synthesis and Evaluation of a 18 F-Labeled Triazinediamine Analogue for Imaging Mutant IDH1 Expression in Gliomas by PET

Synthesis and Evaluation of a 18F‑Labeled Triazinediamine Analogue for Imaging Mutant IDH1 Expression in Gliomas by PET

Comparison of the Hypoxia PET Tracer (18)F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models

Reply: Pharmacokinetic and Pharmacodynamic Modifiers of EF5 Uptake and Binding

Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat model

A simplified synthesis of the hypoxia imaging agent 2-(2-Nitro-1 H -imidazol-1-yl)- N -(2,2,3,3,3-[18 F]pentafluoropropyl)-acetamide ([18 F]EF5)

Preliminary validation of varicella zoster virus thymidine kinase as a novel reporter gene for PET

18F-EF5 PET imaging as an early response biomarker for the hypoxia-activated prodrug SN30000 combined with radiation treatment in a non-small cell lung cancer xenograft model

Necrosis avidity of (99m)Tc(CO)3-labeled pamoic acid derivatives: synthesis and preliminary biological evaluation in animal models of necrosis

Efficient purification and metabolite analysis of radiotracers using high-performance liquid chromatography and on-line solid-phase extraction

[18F]JNJ41510417 a potential PET radioligand for imaging phosphodiesterase-10A in the brain

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