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Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI

Oncogene, 2019-01, Vol.38 (4), p.455-468

2019

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Metabolic targeting of HIF-1α potentiates the therapeutic efficacy of oxaliplatin in colorectal cancer

Oncogene, 2020-01, Vol.39 (2), p.414-427

2020

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HDAC inhibition decreases the expression of EGFR in colorectal cancer cells

PloS one, 2011-03, Vol.6 (3), p.e18087

2011

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Akt Phosphorylation of p300 at Ser-1834 Is Essential for Its Histone Acetyltransferase and Transcriptional Activity

Molecular and Cellular Biology, 2005-08, Vol.25 (15), p.6592-6602

2005

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Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

Autophagy, 2010-11, Vol.6 (8), p.1057-1065

2010

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Inhibition of Autophagy Enhances Anticancer Effects of Atorvastatin in Digestive Malignancies

Cancer research (Chicago, Ill.), 2010-10, Vol.70 (19), p.7699-7709

2010

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Design and Synthesis of Dual-Action Inhibitors Targeting Histone Deacetylases and 3‑Hydroxy-3-methylglutaryl Coenzyme A Reductase for Cancer Treatment

Journal of medicinal chemistry, 2013-05, Vol.56 (9), p.3645-3655

2013

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Neuroinflammation Upregulated Neuronal Toll-Like Receptors 2 and 4 to Drive Synucleinopathy in Neurodegeneration

Frontiers in pharmacology, 2022-03, Vol.13, p.845930-845930

2022

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Statins Increase p21 through Inhibition of Histone Deacetylase Activity and Release of Promoter-Associated HDAC1/2

Cancer research (Chicago, Ill.), 2008-04, Vol.68 (7), p.2375-2383

2008

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Prevention of Colitis and Colitis-Associated Colorectal Cancer by a Novel Polypharmacological Histone Deacetylase Inhibitor

Clinical cancer research, 2016-08, Vol.22 (16), p.4158-4169

2016

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A Novel Anticancer Effect of Thalidomide: Inhibition of Intercellular Adhesion Molecule-1–Mediated Cell Invasion and Metastasis through Suppression of Nuclear Factor-κB

Clinical cancer research, 2006-12, Vol.12 (23), p.7165-7173

2006

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Helicobacter pylori-Induced Invasion and Angiogenesis of Gastric Cells Is Mediated by Cyclooxygenase-2 Induction through TLR2/TLR9 and Promoter Regulation

Journal of Immunology, 2005-12, Vol.175 (12), p.8242-8252

2005

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Methotrexate induces apoptosis through p53/p21-dependent pathway and increases E-cadherin expression through downregulation of HDAC/EZH2

Biochemical pharmacology, 2011-02, Vol.81 (4), p.510-517

2011

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Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress

Oncotarget, 2014-01, Vol.5 (1), p.298-308

2014

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Hepatitis B virus X protein induces IKKα nuclear translocation via Akt-Dependent phosphorylation to promote the motility of hepatocarcinoma cells

Journal of cellular physiology, 2012-04, Vol.227 (4), p.1446-1454

2012

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Signal transduction pathways of inflammatory gene expressions and therapeutic implications

Current pharmaceutical design, 2006-09, Vol.12 (27), p.3497

Chen, Ching-Chow

2006

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Life or death? Autophagy in anticancer therapies with statins and histone deacetylase inhibitors

Autophagy, 2011-01, Vol.7 (1), p.107-108

2011

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Degradation of Epidermal Growth Factor Receptor Mediates Dasatinib-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma Cells

Neoplasia (New York, N.Y.), 2012-06, Vol.14 (6), p.463-IN3

2012

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Corrigendum to “Degradation of Epidermal Growth Factor Receptor Mediates Dasatinib-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma Cells” [ Neoplasia 14 (2012) 463–475]

Neoplasia (New York, N.Y.), 2017-03, Vol.19 (3), p.252-254

2017

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CD1d induction in solid tumor cells by histone deacetylase inhibitors through inhibition of HDAC1/2 and activation of Sp1

Epigenetics, 2012-04, Vol.7 (4), p.390-399

2012

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Dual Targeting of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Histone Deacetylase as a Therapy for Colorectal Cancer

EBioMedicine, 2016-08, Vol.10 (C), p.124-136

2016

Volltextzugriff (PDF)

Phosphorylation of CBP by IKKα Promotes Cell Growth by Switching the Binding Preference of CBP from p53 to NF-κB

Molecular cell, 2007-04, Vol.26 (1), p.75-87

2007

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Mechanisms for Helicobacter pylori CagA‐induced cyclin D1 expression that affect cell cycle

Cellular microbiology, 2006-11, Vol.8 (11), p.1740-1752

2006

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AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine

Oncotarget, 2014-01, Vol.5 (1), p.211-223

2014

Volltextzugriff (PDF)

Loss of IKKβ activity increases p53 stability and p21 expression leading to cell cycle arrest and apoptosis

Journal of cellular and molecular medicine, 2010-03, Vol.14 (3), p.687-698

2010

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Epithelial-mesenchymal transition (EMT) beyond EGFR mutations per se is a common mechanism for acquired resistance to EGFR TKI

Metabolic targeting of HIF-1α potentiates the therapeutic efficacy of oxaliplatin in colorectal cancer

HDAC inhibition decreases the expression of EGFR in colorectal cancer cells

Akt Phosphorylation of p300 at Ser-1834 Is Essential for Its Histone Acetyltransferase and Transcriptional Activity

Autophagy potentiates the anti-cancer effects of the histone deacetylase inhibitors in hepatocellular carcinoma

Inhibition of Autophagy Enhances Anticancer Effects of Atorvastatin in Digestive Malignancies

Design and Synthesis of Dual-Action Inhibitors Targeting Histone Deacetylases and 3‑Hydroxy-3-methylglutaryl Coenzyme A Reductase for Cancer Treatment

Neuroinflammation Upregulated Neuronal Toll-Like Receptors 2 and 4 to Drive Synucleinopathy in Neurodegeneration

Statins Increase p21 through Inhibition of Histone Deacetylase Activity and Release of Promoter-Associated HDAC1/2

Prevention of Colitis and Colitis-Associated Colorectal Cancer by a Novel Polypharmacological Histone Deacetylase Inhibitor

A Novel Anticancer Effect of Thalidomide: Inhibition of Intercellular Adhesion Molecule-1–Mediated Cell Invasion and Metastasis through Suppression of Nuclear Factor-κB

Helicobacter pylori-Induced Invasion and Angiogenesis of Gastric Cells Is Mediated by Cyclooxygenase-2 Induction through TLR2/TLR9 and Promoter Regulation

Methotrexate induces apoptosis through p53/p21-dependent pathway and increases E-cadherin expression through downregulation of HDAC/EZH2

Metformin sensitizes anticancer effect of dasatinib in head and neck squamous cell carcinoma cells through AMPK-dependent ER stress

Hepatitis B virus X protein induces IKKα nuclear translocation via Akt-Dependent phosphorylation to promote the motility of hepatocarcinoma cells

Signal transduction pathways of inflammatory gene expressions and therapeutic implications

Life or death? Autophagy in anticancer therapies with statins and histone deacetylase inhibitors

Degradation of Epidermal Growth Factor Receptor Mediates Dasatinib-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma Cells

Corrigendum to “Degradation of Epidermal Growth Factor Receptor Mediates Dasatinib-Induced Apoptosis in Head and Neck Squamous Cell Carcinoma Cells” [ Neoplasia 14 (2012) 463–475]

CD1d induction in solid tumor cells by histone deacetylase inhibitors through inhibition of HDAC1/2 and activation of Sp1

Dual Targeting of 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase and Histone Deacetylase as a Therapy for Colorectal Cancer

Phosphorylation of CBP by IKKα Promotes Cell Growth by Switching the Binding Preference of CBP from p53 to NF-κB

Mechanisms for Helicobacter pylori CagA‐induced cyclin D1 expression that affect cell cycle

AID downregulation is a novel function of the DNMT inhibitor 5-aza-deoxycytidine

Loss of IKKβ activity increases p53 stability and p21 expression leading to cell cycle arrest and apoptosis

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