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GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

Nature medicine, 2017-10, Vol.23 (10), p.1150-1157

2017

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TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway

PloS one, 2015-10, Vol.10 (10), p.e0140694-e0140694

2015

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Avidity confers FcγR binding and immune effector function to aglycosylated immunoglobulin G1

Journal of molecular recognition, 2012-03, Vol.25 (3), p.147-154

2012

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Membrane protein folding: beyond the two stage model

FEBS letters, 2003-11, Vol.555 (1), p.122-125

2003

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Rapid Topology Mapping of Escherichia coli Inner-Membrane Proteins by Prediction and PhoA/GFP Fusion Analysis

Proceedings of the National Academy of Sciences - PNAS, 2002-03, Vol.99 (5), p.2690-2695

2002

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Membrane Assembly of the Cannabinoid Receptor 1: Impact of a Long N-Terminal Tail

Molecular pharmacology, 2003-09, Vol.64 (3), p.570-577

2003

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Tumor cell-directed STING agonist antibody-drug conjugates induce type III interferons and anti-tumor innate immune responses

Nature communications, 2024-07, Vol.15 (1), p.5842-19, Article 5842

2024

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Transmembrane homodimerization of receptor-like protein tyrosine phosphatases

FEBS letters, 2005-07, Vol.579 (17), p.3855-3858

2005

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620 Tumor cell-intrinsic STING pathway is activated in the presence of cues from immune cells and contributes to the anti-tumor activity of tumor cell-targeted STING agonist antibody-drug conjugates

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A373-A373

2020

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Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody-Drug Conjugate for the Treatment of Cancer

Molecular cancer therapeutics, 2023-09, Vol.22 (9), p.999-1012

2023

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Ligand Binding and Modulation of Cyclic AMP Levels Depend on the Chemical Nature of Residue 192 of the Human Cannabinoid Receptor 1

Journal of neurochemistry, 1998-01, Vol.70 (1), p.366-373

1998

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Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo

European journal of pharmacology, 2009-08, Vol.616 (1), p.346-352

2009

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Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity

European journal of pharmacology, 2009-03, Vol.606 (1), p.17-24

2009

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The third transmembrane helix of the cannabinoid receptor plays a role in the selectivity of aminoalkylindoles for CB2, peripheral cannabinoid receptor

The Journal of pharmacology and experimental therapeutics, 1999-11, Vol.291 (2), p.837

1999

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Charge pair interactions in a model transmembrane helix in the ER membrane

Journal of molecular biology, 2000-10, Vol.303 (1), p.1-5

2000

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Membrane proteins: shaping up

Trends in biochemical sciences (Amsterdam. Regular ed.), 2002-05, Vol.27 (5), p.231-234

2002

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Abstract 907: XMT-1660, a B7-H4-targeted Dolasynthen antibody-drug conjugate for the treatment of breast cancer

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.907-907

2021

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Abstract 2894: XMT-1592, a site-specific Dolasynthen-based NaPi2b-targeted antibody-drug conjugate for the treatment of ovarian cancer and lung adenocarcinoma

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.2894-2894

2020

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Abstract 6706: Systemic administration of STING agonist antibody-drug conjugates elicit potent anti-tumor immune responses with minimal induction of circulating cytokines

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6706-6706

2020

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Abstract 2687: Dolasynthen–a novel, homogeneous Auristatin F hydroxypropyl amide antibody-drug conjugate platform

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2687-2687

2019

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TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway: e0140694

PloS one, 2015-10, Vol.10 (10)

2015

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Therapeutic Antibodies in Clinical Use and Leading Clinical Candidates

Therapeutic Monoclonal Antibodies, 2009, p.711-762

2009

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Involvement of the Carboxyl Terminus of the Third Intracellular Loop of the Cannabinoid CB1 Receptor in Constitutive Activation of G s

Journal of neurochemistry, 1999-05, Vol.72 (5), p.2032-2038

1999

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Involvement of the Carboxyl Terminus of the Third Intracellular Loop of the Cannabinoid CB1 Receptor in Constitutive Activation of Gs

Journal of neurochemistry, 1999-05, Vol.72 (5), p.2032-2038

1999

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Mapping the ligand binding site(s) of the cannabinoid receptor

Chin, Chen-ni

1999

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GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway

Avidity confers FcγR binding and immune effector function to aglycosylated immunoglobulin G1

Membrane protein folding: beyond the two stage model

Rapid Topology Mapping of Escherichia coli Inner-Membrane Proteins by Prediction and PhoA/GFP Fusion Analysis

Membrane Assembly of the Cannabinoid Receptor 1: Impact of a Long N-Terminal Tail

Tumor cell-directed STING agonist antibody-drug conjugates induce type III interferons and anti-tumor innate immune responses

Transmembrane homodimerization of receptor-like protein tyrosine phosphatases

620 Tumor cell-intrinsic STING pathway is activated in the presence of cues from immune cells and contributes to the anti-tumor activity of tumor cell-targeted STING agonist antibody-drug conjugates

Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody-Drug Conjugate for the Treatment of Cancer

Ligand Binding and Modulation of Cyclic AMP Levels Depend on the Chemical Nature of Residue 192 of the Human Cannabinoid Receptor 1

Suppression of PC-1/ENPP-1 expression improves insulin sensitivity in vitro and in vivo

Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity

The third transmembrane helix of the cannabinoid receptor plays a role in the selectivity of aminoalkylindoles for CB2, peripheral cannabinoid receptor

Charge pair interactions in a model transmembrane helix in the ER membrane

Membrane proteins: shaping up

Abstract 907: XMT-1660, a B7-H4-targeted Dolasynthen antibody-drug conjugate for the treatment of breast cancer

Abstract 2894: XMT-1592, a site-specific Dolasynthen-based NaPi2b-targeted antibody-drug conjugate for the treatment of ovarian cancer and lung adenocarcinoma

Abstract 6706: Systemic administration of STING agonist antibody-drug conjugates elicit potent anti-tumor immune responses with minimal induction of circulating cytokines

Abstract 2687: Dolasynthen–a novel, homogeneous Auristatin F hydroxypropyl amide antibody-drug conjugate platform

TIM-3 Suppresses Anti-CD3/CD28-Induced TCR Activation and IL-2 Expression through the NFAT Signaling Pathway: e0140694

Therapeutic Antibodies in Clinical Use and Leading Clinical Candidates

Involvement of the Carboxyl Terminus of the Third Intracellular Loop of the Cannabinoid CB1 Receptor in Constitutive Activation of G s

Involvement of the Carboxyl Terminus of the Third Intracellular Loop of the Cannabinoid CB1 Receptor in Constitutive Activation of Gs

Mapping the ligand binding site(s) of the cannabinoid receptor

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