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Small molecule recognition of disease-relevant RNA structures

Chemical Society reviews, 2020-10, Vol.49 (19), p.7167-7199

2020

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Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit

Journal of the American Chemical Society, 2017-03, Vol.139 (9), p.3446-3455

2017

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Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer

Proceedings of the National Academy of Sciences - PNAS, 2020-02, Vol.117 (5), p.2406-2411

2020

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Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs

ACS chemical biology, 2016-06, Vol.11 (6), p.1720-1728

2016

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Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA

Journal of the American Chemical Society, 2022-07, Vol.144 (26), p.11620-11625

2022

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A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to Herceptin

Journal of the American Chemical Society, 2019-02, Vol.141 (7), p.2960-2974

2019

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Vagus Nerve Stimulation Reduces Cocaine Seeking and Alters Plasticity in the Extinction Network

Learning & memory (Cold Spring Harbor, N.Y.), 2017-01, Vol.24 (1), p.35-42

2017

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Design of small molecules targeting RNA structure from sequence

Chemical Society reviews, 2020-10, Vol.49 (2), p.7252-727

2020

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Incorporating Chemical Modification Constraints into a Dynamic Programming Algorithm for Prediction of RNA Secondary Structure

Proceedings of the National Academy of Sciences - PNAS, 2004-05, Vol.101 (19), p.7287-7292

2004

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The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology

PloS one, 2019-07, Vol.14 (7), p.e0219210-e0219210

2019

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RNA structural analysis of the MYC mRNA reveals conserved motifs that affect gene expression

PloS one, 2019-06, Vol.14 (6), p.e0213758-e0213758

2019

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Vagus nerve stimulation enhances extinction of conditioned fear and modulates plasticity in the pathway from the ventromedial prefrontal cortex to the amygdala

Frontiers in behavioral neuroscience, 2014-09, Vol.8, p.327-327

2014

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DNA‐Encoded Libraries and Their Application to RNA

Israel journal of chemistry, 2023-10, Vol.63 (10-11), p.n/a

2023

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Relapse to cocaine seeking is regulated by medial habenula NR4A2/NURR1 in mice

Cell reports (Cambridge), 2024-03, Vol.43 (3), p.113956-113956, Article 113956

2024

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CONSUMER PERCEPTION OF FAT REDUCTION IN CHEESE

Journal of sensory studies, 2009-12, Vol.24 (6), p.902-921

2009

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Cocaine induces paradigm-specific changes to the transcriptome within the ventral tegmental area

Neuropsychopharmacology (New York, N.Y.), 2021-09, Vol.46 (10), p.1768-1779

2021

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Vagus nerve stimulation during extinction learning reduces conditioned place preference and context-induced reinstatement of cocaine seeking

Brain stimulation, 2019-11, Vol.12 (6), p.1448-1455

2019

Volltextzugriff (PDF)

Play Therapy and Telemental Health: Foundations, Populations, and Interventions

Stone, Jessica

1st, 2022

Volltextzugriff (PDF)

Targeting RNA structures with small molecules

Nature reviews. Drug discovery, 2022-10, Vol.21 (10), p.736-762

2022

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Acute Vagus Nerve Stimulation Facilitates Short Term Memory and Cognitive Flexibility in Rats

Brain sciences, 2022-08, Vol.12 (9), p.1137

2022

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Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules

Nature communications, 2013-06, Vol.4 (1), p.2044-2044, Article 2044

2013

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How We Think about Targeting RNA with Small Molecules

Journal of medicinal chemistry, 2020-09, Vol.63 (17), p.8880-8900

2020

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Severe mental illness, common mental disorders, and neurodevelopmental conditions amongst 9088 lower court attendees in London, UK

BMC psychiatry, 2022-08, Vol.22 (1), p.1-551, Article 551

2022

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Defining RNA–Small Molecule Affinity Landscapes Enables Design of a Small Molecule Inhibitor of an Oncogenic Noncoding RNA

ACS central science, 2017-03, Vol.3 (3), p.205-216

2017

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Small molecule recognition of disease-relevant RNA structures

Small Molecule Inhibition of microRNA-210 Reprograms an Oncogenic Hypoxic Circuit

Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer

Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs

Transcriptome-Wide Mapping of Small-Molecule RNA-Binding Sites in Cells Informs an Isoform-Specific Degrader of QSOX1 mRNA

A Designed Small Molecule Inhibitor of a Non-Coding RNA Sensitizes HER2 Negative Cancers to Herceptin

Vagus Nerve Stimulation Reduces Cocaine Seeking and Alters Plasticity in the Extinction Network

Design of small molecules targeting RNA structure from sequence

Incorporating Chemical Modification Constraints into a Dynamic Programming Algorithm for Prediction of RNA Secondary Structure

The RNA encoding the microtubule-associated protein tau has extensive structure that affects its biology

RNA structural analysis of the MYC mRNA reveals conserved motifs that affect gene expression

Vagus nerve stimulation enhances extinction of conditioned fear and modulates plasticity in the pathway from the ventromedial prefrontal cortex to the amygdala

DNA‐Encoded Libraries and Their Application to RNA

Generation of a humanized Aβ expressing mouse demonstrating aspects of Alzheimer's disease-like pathology

Relapse to cocaine seeking is regulated by medial habenula NR4A2/NURR1 in mice

CONSUMER PERCEPTION OF FAT REDUCTION IN CHEESE

Cocaine induces paradigm-specific changes to the transcriptome within the ventral tegmental area

Vagus nerve stimulation during extinction learning reduces conditioned place preference and context-induced reinstatement of cocaine seeking

Play Therapy and Telemental Health: Foundations, Populations, and Interventions

Targeting RNA structures with small molecules

Acute Vagus Nerve Stimulation Facilitates Short Term Memory and Cognitive Flexibility in Rats

Induction and reversal of myotonic dystrophy type 1 pre-mRNA splicing defects by small molecules

How We Think about Targeting RNA with Small Molecules

Severe mental illness, common mental disorders, and neurodevelopmental conditions amongst 9088 lower court attendees in London, UK

Defining RNA–Small Molecule Affinity Landscapes Enables Design of a Small Molecule Inhibitor of an Oncogenic Noncoding RNA

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