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BIVV001 Fusion Protein as Factor VIII Replacement Therapy for Hemophilia A

The New England journal of medicine, 2020-09, Vol.383 (11), p.1018-1027

2020

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Efanesoctocog alfa elicits functional clot formation that is indistinguishable to that of recombinant factor VIII

Journal of thrombosis and haemostasis, 2022-07, Vol.20 (7), p.1674-1683

2022

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A global comparative field study to evaluate the factor VIII activity of efanesoctocog alfa by one‐stage clotting and chromogenic substrate assays at clinical haemostasis laboratories

Haemophilia : the official journal of the World Federation of Hemophilia, 2024-01, Vol.30 (1), p.214-223

2024

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INF2 Is a WASP Homology 2 Motif-containing Formin That Severs Actin Filaments and Accelerates Both Polymerization and Depolymerization

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26754-26767

2006

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Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport

Journal of neurochemistry, 2009-10, Vol.111 (2), p.417-427

2009

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INF2 is an endoplasmic reticulum-associated formin protein

Journal of cell science, 2009-05, Vol.122 (9), p.1430-1440

2009

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Mapping the interaction between factor VIII and von Willebrand factor by electron microscopy and mass spectrometry

Blood, 2015-08, Vol.126 (8), p.935-938

2015

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Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice

Cellular immunology, 2016-03, Vol.301, p.30-39

2016

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The many faces of actin: matching assembly factors with cellular structures

Nature cell biology, 2007-10, Vol.9 (10), p.1110-1121

2007

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Engulfment adapter PTB domain containing 1 interacts with and affects processing of the amyloid-β precursor protein

Neurobiology of aging, 2012-04, Vol.33 (4), p.732-743

2012

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The von Willebrand factor D′D3 assembly and structural principles for factor VIII binding and concatemer biogenesis

Blood, 2019-04, Vol.133 (14), p.1523-1533

2019

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Development of a Quantitative Systems Pharmacology Model to Explore Hemostatic Equivalency of Antithrombin Lowering

Blood, 2022-11, Vol.140 (Supplement 1), p.5606-5607

2022

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Efanesoctocog Alfa Half-Life and Clearance Are Independent of von Willebrand Factor in Severe Hemophilia A: A Post Hoc Analysis from Phase 1/2a Studies

Blood, 2021-11, Vol.138 (Supplement 1), p.1035-1035

2021

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Prolonged Half-Life and Improved Recovery of Recombinant Factor IX-XTEN Fusion Proteins in Hemophilia B Mouse Model

Blood, 2015-12, Vol.126 (23), p.2271-2271

2015

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Evaluation of Enhanced in Vitro Plasma Stability of a Novel Long Acting Recombinant FVIIIFc-VWF-XTEN Fusion Protein

Blood, 2015-12, Vol.126 (23), p.2279-2279

2015

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Recombinant FVIIIFc-VWF-XTEN Demonstrates Significant Bioavailability Following Subcutaneous Administration in Hemophilia A Mice

Blood, 2015-12, Vol.126 (23), p.3492-3492

2015

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The Effect of Factor IXa on Thrombin Generation Activity Determination: rFIXFc Vs. BeneFIX

Blood, 2011-11, Vol.118 (21), p.2266-2266

2011

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The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis

Blood, 2019-04, Vol.133 (14), p.1523-1533

2019

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Oropharyngeal second branchial cleft cyst

International journal of pediatric otorhinolaryngology extra, 2007-12, Vol.2 (4), p.222-224

2007

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Hypobaric hypoxia induced renal damage is mediated by altering redox pathway

PloS one, 2018-07, Vol.13 (7), p.e0195701-e0195701

2018

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Effect of Raja yoga Meditation on psychological and functional outcomes in spinal cord injury patients

International journal of yoga, 2021-01, Vol.14 (1), p.36-42

2021

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Efficacy of convalescent plasma therapy in the patient with COVID-19: a randomised control trial (COPLA-II trial)

BMJ open, 2022-04, Vol.12 (4), p.e055189-e055189

2022

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Comparison of safety and efficacy of convalescent plasma with fresh frozen plasma in severe covid-19 patients

Anais da Academia Brasileira de Ciências, 2022-01, Vol.94 (4), p.e20210202-e20210202

2022

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SARS-CoV-2 among liver transplant recipients: Clinical course and mutational analysis

Journal of clinical virology plus, 2024-06, Vol.4 (2), p.100181, Article 100181

2024

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BIVV001 Fusion Protein as Factor VIII Replacement Therapy for Hemophilia A

Efanesoctocog alfa elicits functional clot formation that is indistinguishable to that of recombinant factor VIII

BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice

A global comparative field study to evaluate the factor VIII activity of efanesoctocog alfa by one‐stage clotting and chromogenic substrate assays at clinical haemostasis laboratories

INF2 Is a WASP Homology 2 Motif-containing Formin That Severs Actin Filaments and Accelerates Both Polymerization and Depolymerization

Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport

INF2 is an endoplasmic reticulum-associated formin protein

Mapping the interaction between factor VIII and von Willebrand factor by electron microscopy and mass spectrometry

Recombinant factor VIII Fc (rFVIIIFc) fusion protein reduces immunogenicity and induces tolerance in hemophilia A mice

The many faces of actin: matching assembly factors with cellular structures

Engulfment adapter PTB domain containing 1 interacts with and affects processing of the amyloid-β precursor protein

The von Willebrand factor D′D3 assembly and structural principles for factor VIII binding and concatemer biogenesis

Development of a Quantitative Systems Pharmacology Model to Explore Hemostatic Equivalency of Antithrombin Lowering

Efanesoctocog Alfa Half-Life and Clearance Are Independent of von Willebrand Factor in Severe Hemophilia A: A Post Hoc Analysis from Phase 1/2a Studies

Prolonged Half-Life and Improved Recovery of Recombinant Factor IX-XTEN Fusion Proteins in Hemophilia B Mouse Model

Evaluation of Enhanced in Vitro Plasma Stability of a Novel Long Acting Recombinant FVIIIFc-VWF-XTEN Fusion Protein

Recombinant FVIIIFc-VWF-XTEN Demonstrates Significant Bioavailability Following Subcutaneous Administration in Hemophilia A Mice

The Effect of Factor IXa on Thrombin Generation Activity Determination: rFIXFc Vs. BeneFIX

The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis

Oropharyngeal second branchial cleft cyst

Hypobaric hypoxia induced renal damage is mediated by altering redox pathway

Effect of Raja yoga Meditation on psychological and functional outcomes in spinal cord injury patients

Efficacy of convalescent plasma therapy in the patient with COVID-19: a randomised control trial (COPLA-II trial)

Comparison of safety and efficacy of convalescent plasma with fresh frozen plasma in severe covid-19 patients

SARS-CoV-2 among liver transplant recipients: Clinical course and mutational analysis

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