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Smac mimetics and innate immune stimuli synergize to promote tumor death

Nature biotechnology, 2014-02, Vol.32 (2), p.182-190

2014

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Degradation of Survivin by the X-linked Inhibitor of Apoptosis (XIAP)-XAF1 Complex

The Journal of biological chemistry, 2007-09, Vol.282 (36), p.26202-26209

2007

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Down-regulation of c-FLIP Enhances Death of Cancer Cells by Smac Mimetic Compound

Cancer research (Chicago, Ill.), 2009-10, Vol.69 (19), p.7729-7738

2009

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Translational Induction of the Inhibitor of Apoptosis Protein HIAP2 during Endoplasmic Reticulum Stress Attenuates Cell Death and Is Mediated via an Inducible Internal Ribosome Entry Site Element

The Journal of biological chemistry, 2004-04, Vol.279 (17), p.17148-17157

2004

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Modulation of immune signalling by inhibitors of apoptosis

Trends in immunology, 2012-11, Vol.33 (11), p.535-545

2012

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Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK

Nature immunology, 2008-12, Vol.9 (12), p.1371-1378

2008

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Tyrosine phosphorylation of the N‐methyl‐d‐aspartate receptor by exogenous and postsynaptic density‐associated Src‐family kinases

Journal of neurochemistry, 2001-08, Vol.78 (3), p.524-534

2001

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Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta

BMC cancer, 2007-03, Vol.7 (1), p.52-52, Article 52

2007

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The transcription factor SP3 drives TNF-α expression in response to Smac mimetics

Science signaling, 2019-01, Vol.12 (566)

2019

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The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways

Molecular biology of the cell, 2008-07, Vol.19 (7), p.2729-2740

2008

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Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: A role for the IAPs

Experimental cell research, 2006-07, Vol.312 (12), p.2347-2357

2006

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Smac Mimetic Compounds Potentiate Interleukin-1β-mediated Cell Death

The Journal of biological chemistry, 2010-12, Vol.285 (52), p.40612-40623

2010

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X-linked inhibitor of apoptosis antagonism : Strategies in cancer treatment

Clinical cancer research, 2006-06, Vol.12 (11), p.3238-3242

2006

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Monitor – biology

Drug discovery today, 2005-08, Vol.10 (15), p.1073-1073

2005

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The role of XAF1 in cancer

Current opinion in investigational drugs (London, England : 2000), 2007-06, Vol.8 (6), p.469

2007

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Inhibition of protein kinase C reduces ischemia‐induced tyrosine phosphorylation of the N‐methyl‐d‐aspartate receptor

Journal of neurochemistry, 2003-09, Vol.86 (6), p.1441-1449

2003

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Altered Association of Protein Tyrosine Kinases With Postsynaptic Densities After Transient Cerebral Ischemia in the Rat Brain

Journal of cerebral blood flow and metabolism, 2000-03, Vol.20 (3), p.505-512

2000

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Isolation and characterization of LCHN: a novel factor induced by transient global ischemia in the adult rat hippocampus

Journal of neurochemistry, 2007-04, Vol.101 (1), p.263-273

2007

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Increased phosphorylation of the NR1 subunit of the NMDA receptor following cerebral ischemia

Journal of neurochemistry, 2001-09, Vol.78 (5), p.1179-1182

2001

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Lateral Hypothalamic Signaling Mechanisms Underlying Feeding Stimulation: Differential Contributions of Src Family Tyrosine Kinases to Feeding Triggered Either by NMDA Injection or by Food Deprivation

The Journal of neuroscience, 2004-11, Vol.24 (47), p.10603-10615

2004

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Monitor – Biology

Drug discovery today, 2004, Vol.9 (6), p.287-290

2004

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Monitor – biology

Drug discovery today, 2005-07, Vol.10 (14), p.1008-1009

2005

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Monitor – biology

Drug discovery today, 2005-05, Vol.10 (10), p.736-737

2005

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The Effect of Transient Global Ischemia on the Interaction of Src and Fyn with the N-Methyl-d-Aspartate Receptor and Postsynaptic Densities: Possible Involvement of Src Homology 2 Domains

Journal of cerebral blood flow and metabolism, 1999-08, Vol.19 (8), p.880-888

1999

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Smac mimetics and innate immune stimuli synergize to promote tumor death

Degradation of Survivin by the X-linked Inhibitor of Apoptosis (XIAP)-XAF1 Complex

Down-regulation of c-FLIP Enhances Death of Cancer Cells by Smac Mimetic Compound

Translational Induction of the Inhibitor of Apoptosis Protein HIAP2 during Endoplasmic Reticulum Stress Attenuates Cell Death and Is Mediated via an Inducible Internal Ribosome Entry Site Element

Modulation of immune signalling by inhibitors of apoptosis

Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK

Tyrosine phosphorylation of the N‐methyl‐d‐aspartate receptor by exogenous and postsynaptic density‐associated Src‐family kinases

Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta

The transcription factor SP3 drives TNF-α expression in response to Smac mimetics

The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways

Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: A role for the IAPs

Smac Mimetic Compounds Potentiate Interleukin-1β-mediated Cell Death

X-linked inhibitor of apoptosis antagonism : Strategies in cancer treatment

Monitor – biology

The role of XAF1 in cancer

Inhibition of protein kinase C reduces ischemia‐induced tyrosine phosphorylation of the N‐methyl‐d‐aspartate receptor

Altered Association of Protein Tyrosine Kinases With Postsynaptic Densities After Transient Cerebral Ischemia in the Rat Brain

Isolation and characterization of LCHN: a novel factor induced by transient global ischemia in the adult rat hippocampus

Increased phosphorylation of the NR1 subunit of the NMDA receptor following cerebral ischemia

Lateral Hypothalamic Signaling Mechanisms Underlying Feeding Stimulation: Differential Contributions of Src Family Tyrosine Kinases to Feeding Triggered Either by NMDA Injection or by Food Deprivation

Monitor – Biology

Monitor – biology

Monitor – biology

The Effect of Transient Global Ischemia on the Interaction of Src and Fyn with the N-Methyl-d-Aspartate Receptor and Postsynaptic Densities: Possible Involvement of Src Homology 2 Domains

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