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Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis

Toxicological sciences, 2018-08, Vol.164 (2), p.428-438

2018

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Addressing the Clinical Importance of Equilibrative Nucleoside Transporters in Drug Discovery and Development

Clinical pharmacology and therapeutics, 2023-10, Vol.114 (4), p.780-794

2023

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Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease

Amino acids, 2015-03, Vol.47 (3), p.603-615

2015

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Impaired N‐linked glycosylation of uptake and efflux transporters in human non‐alcoholic fatty liver disease

Liver international, 2017-07, Vol.37 (7), p.1074-1081

2017

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Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease

Toxicology and applied pharmacology, 2013-04, Vol.268 (2), p.132-140

2013

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Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats

Drug metabolism and disposition, 2003-11, Vol.31 (11), p.1337

2003

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Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

Drug metabolism and disposition, 2009-10, Vol.37 (10), p.2087

2009

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The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease

Toxicological sciences, 2014-01, Vol.137 (1), p.26-35

2014

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PF‐07321332 (Nirmatrelvir) does not interact with human ENT1 or ENT2: Implications for COVID‐19 patients

Clinical and translational science, 2022-07, Vol.15 (7), p.1599-1605

2022

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Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease

Drug metabolism and disposition, 2013-03, Vol.41 (3), p.554

2013

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Variations in ATP-binding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease

Drug metabolism and disposition, 2011-12, Vol.39 (12), p.2395

2011

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Analysis of global and absorption, distribution, metabolism, and elimination gene expression in the progressive stages of human nonalcoholic fatty liver disease

Drug metabolism and disposition, 2011-10, Vol.39 (10), p.1954

2011

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Modeling human nonalcoholic steatohepatitis-associated changes in drug transporter expression using experimental rodent models

Drug metabolism and disposition, 2014-04, Vol.42 (4), p.586

2014

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Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis

Drug metabolism and disposition, 2017-12, Vol.45 (12), p.1317-1325

2017

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Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis

The Journal of pharmacology and experimental therapeutics, 2015-03, Vol.352 (3), p.462

2015

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Synergistic interaction between genetics and disease on pravastatin disposition

Journal of hepatology, 2014-07, Vol.61 (1), p.139-147

2014

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Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis

Drug metabolism and disposition, 2015-06, Vol.43 (6), p.829-835

2015

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Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis

Journal of biochemical and molecular toxicology, 2018-03, Vol.32 (3), p.e22035-n/a

2018

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Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis

Toxicological sciences, 2014-11, Vol.142 (1), p.45-55

2014

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Drug disposition alterations in liver disease: extrahepatic effects in cholestasis and nonalcoholic steatohepatitis

Expert opinion on drug metabolism & toxicology, 2014-09, Vol.10 (9), p.1209-1219

2014

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Generation of a hTERT-Immortalized Human Sertoli Cell Model to Study Transporter Dynamics at the Blood-Testis Barrier

Pharmaceutics, 2020-10, Vol.12 (11), p.1005

2020

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Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis

Drug metabolism and disposition, 2012-03, Vol.40 (3), p.450

2012

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Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice

Drug metabolism and disposition, 2005-07, Vol.33 (7), p.947

2005

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Alcohol cirrhosis alters nuclear receptor and drug transporter expression in human liver

Drug metabolism and disposition, 2013-05, Vol.41 (5), p.1148

2013

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Predicting disruptions to drug pharmacokinetics and the risk of adverse drug reactions in non-alcoholic steatohepatitis patients

Acta pharmaceutica Sinica. B, 2023-01, Vol.13 (1), p.1-28

2023

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Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis

Addressing the Clinical Importance of Equilibrative Nucleoside Transporters in Drug Discovery and Development

Branched chain amino acid metabolism profiles in progressive human nonalcoholic fatty liver disease

Impaired N‐linked glycosylation of uptake and efflux transporters in human non‐alcoholic fatty liver disease

Decreased hepatotoxic bile acid composition and altered synthesis in progressive human nonalcoholic fatty liver disease

Constitutive expression of various xenobiotic and endobiotic transporter mRNAs in the choroid plexus of rats

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease

PF‐07321332 (Nirmatrelvir) does not interact with human ENT1 or ENT2: Implications for COVID‐19 patients

Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease

Variations in ATP-binding cassette transporter regulation during the progression of human nonalcoholic fatty liver disease

Analysis of global and absorption, distribution, metabolism, and elimination gene expression in the progressive stages of human nonalcoholic fatty liver disease

Modeling human nonalcoholic steatohepatitis-associated changes in drug transporter expression using experimental rodent models

Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis

Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis

Synergistic interaction between genetics and disease on pravastatin disposition

Altered regulation of hepatic efflux transporters disrupts acetaminophen disposition in pediatric nonalcoholic steatohepatitis

Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis

Increased susceptibility to methotrexate-induced toxicity in nonalcoholic steatohepatitis

Drug disposition alterations in liver disease: extrahepatic effects in cholestasis and nonalcoholic steatohepatitis

Generation of a hTERT-Immortalized Human Sertoli Cell Model to Study Transporter Dynamics at the Blood-Testis Barrier

Molecular mechanism of altered ezetimibe disposition in nonalcoholic steatohepatitis

Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice

Alcohol cirrhosis alters nuclear receptor and drug transporter expression in human liver

Predicting disruptions to drug pharmacokinetics and the risk of adverse drug reactions in non-alcoholic steatohepatitis patients

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