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BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program

Science (American Association for the Advancement of Science), 2010-12, Vol.330 (6009), p.1390-1393

2010

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BAX activation is initiated at a novel interaction site

Nature, 2008-10, Vol.455 (7216), p.1076-1081

2008

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Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Science (American Association for the Advancement of Science), 2001-04, Vol.292 (5517), p.727-730

2001

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Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

Molecular cell, 2009-11, Vol.36 (3), p.487-499

2009

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Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

Nature cell biology, 2006-12, Vol.8 (12), p.1348-1358

2006

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VDAC2 Inhibits BAK Activation and Mitochondrial Apoptosis

Science (American Association for the Advancement of Science), 2003-07, Vol.301 (5632), p.513-517

2003

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Gender Differences of Thromboembolic Events in Atrial Fibrillation

The American journal of cardiology, 2016-03, Vol.117 (6), p.1021-1027

2016

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Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint

Nature (London), 2010-09, Vol.467 (7313), p.343-346

2010

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Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (20), p.9035-9042

2010

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PUMA and BIM are required for oncogene inactivation-induced apoptosis

Science signaling, 2013-03, Vol.6 (268), p.ra20

2013

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p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage

Proceedings of the National Academy of Sciences - PNAS, 2009-01, Vol.106 (4), p.1093-1098

2009

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A Pharmacologic Inhibitor of the Protease Taspase1 Effectively Inhibits Breast and Brain Tumor Growth

Cancer research (Chicago, Ill.), 2012-02, Vol.72 (3), p.736-746

2012

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Conversion of Bcl-2 to a bax-like death effector by caspases

Science (American Association for the Advancement of Science), 1997-12, Vol.278 (5345), p.1966-1968

1997

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Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression

Genes & development, 2006-09, Vol.20 (17), p.2397-2409

2006

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Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

eLife, 2013-08, Vol.2, p.e00772-e00772

2013

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The VDAC2-BAK rheostat controls thymocyte survival

Science signaling, 2009-08, Vol.2 (85), p.ra48

2009

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Bax and Bak Do Not Exhibit Functional Redundancy in Mediating Radiation-Induced Endothelial Apoptosis in the Intestinal Mucosa

International journal of radiation oncology, biology, physics, 2008-03, Vol.70 (3), p.804-815

2008

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A Bcl-2 Homolog Encoded by Kaposi Sarcoma-Associated Virus, Human Herpesvirus 8, Inhibits Apoptosis but does not Heterodimerize with Bax or Bak

Proceedings of the National Academy of Sciences - PNAS, 1997-01, Vol.94 (2), p.690-694

1997

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Occipital glial heterotopia: A rare entity with important clinical considerations

Otolaryngology case reports, 2021-11, Vol.21, p.100383, Article 100383

2021

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MLL fusions: Pathways to leukemia

Cancer biology & therapy, 2009-07, Vol.8 (13), p.1204-1211

2009

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Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis

Cancer research (Chicago, Ill.), 2010-07, Vol.70 (13), p.5358-5367

2010

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Proapoptotic BAX and BAK control multiple initiator caspases

EMBO reports, 2005-04, Vol.6 (4), p.379-385

2005

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Modulation of cell death by Bcl-xL through caspase interaction

Proceedings of the National Academy of Sciences - PNAS, 1998-01, Vol.95 (2), p.554-559

1998

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Use of genome sequencing to hunt for cryptic second-hit variants: analysis of 31 cases recruited to the 100 000 Genomes Project

Journal of medical genetics, 2023-12, Vol.60 (12), p.1235-1244

2023

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A Palindrome-Like Structure on 16p13.3 Is Associated with the Formation of Complex Structural Variations and SRRM2 Haploinsufficiency

Human mutation, 2023-04, Vol.2023, p.1-9

2023

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BID, BIM, and PUMA Are Essential for Activation of the BAX- and BAK-Dependent Cell Death Program

BAX activation is initiated at a novel interaction site

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

VDAC2 Inhibits BAK Activation and Mitochondrial Apoptosis

Gender Differences of Thromboembolic Events in Atrial Fibrillation

Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint

Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy

PUMA and BIM are required for oncogene inactivation-induced apoptosis

p53-cathepsin axis cooperates with ROS to activate programmed necrotic death upon DNA damage

A Pharmacologic Inhibitor of the Protease Taspase1 Effectively Inhibits Breast and Brain Tumor Growth

Conversion of Bcl-2 to a bax-like death effector by caspases

Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression

Bax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in mice

The VDAC2-BAK rheostat controls thymocyte survival

Bax and Bak Do Not Exhibit Functional Redundancy in Mediating Radiation-Induced Endothelial Apoptosis in the Intestinal Mucosa

A Bcl-2 Homolog Encoded by Kaposi Sarcoma-Associated Virus, Human Herpesvirus 8, Inhibits Apoptosis but does not Heterodimerize with Bax or Bak

Occipital glial heterotopia: A rare entity with important clinical considerations

MLL fusions: Pathways to leukemia

Taspase1 functions as a non-oncogene addiction protease that coordinates cancer cell proliferation and apoptosis

Proapoptotic BAX and BAK control multiple initiator caspases

Modulation of cell death by Bcl-xL through caspase interaction

Use of genome sequencing to hunt for cryptic second-hit variants: analysis of 31 cases recruited to the 100 000 Genomes Project

A Palindrome-Like Structure on 16p13.3 Is Associated with the Formation of Complex Structural Variations and SRRM2 Haploinsufficiency

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