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Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone

British journal of clinical pharmacology, 1999-09, Vol.48 (3), p.424-432

1999

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Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

Xenobiotica, 1995, Vol.25 (3), p.261-270

1995

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Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver

Drug metabolism and disposition, 1995-02, Vol.23 (2), p.251

1995

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In vitro identification of the P450 enzymes responsible for the metabolism of ropinirole

Drug metabolism and disposition, 1997-07, Vol.25 (7), p.840

1997

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Disposition of ropinirole in animals and man

Xenobiotica, 1999, Vol.29 (3), p.311-325

RAMJI, J. V.

1999

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Characterization of the inhibition of P4501A2 by furafylline

Xenobiotica, 1994, Vol.24 (6), p.517-526

1994

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Characterisation of the cytochrome P450 enzymes involved in the in vitro metabolism of granisetron

British journal of clinical pharmacology, 1994-12, Vol.38 (6), p.557-566

1994

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Determination of P4501A2 activity in human liver microsomes using [3-14C-methyl]caffeine

Xenobiotica, 1995, Vol.25 (9), p.917-927

1995

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Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes

Chemical research in toxicology, 1994-11, Vol.7 (6), p.836-842

1994

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Crystal Structure of Human Cytochrome P450 2D6

The Journal of biological chemistry, 2006-03, Vol.281 (11), p.7614-7622

2006

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Induction of cytochrome P4503A by the antiglucocorticoid mifepristone and a novel hypocholesterolaemic drug

Drug metabolism and disposition, 1997-06, Vol.25 (6), p.757

1997

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Comparative drug metabolism of diazepam in hepatocytes isolated from man, rat, monkey and dog

Biochemical pharmacology, 1989-05, Vol.38 (10), p.1657-1665

1989

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Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes

Drug metabolism and disposition, 1993-01, Vol.21 (1), p.18

1993

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Diazepam metabolism in cultured hepatocytes from rat, rabbit, dog, guinea pig, and man

Drug metabolism and disposition, 1987-05, Vol.15 (3), p.312

1987

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Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent

Drug metabolism and disposition, 1994-01, Vol.22 (1), p.124

1994

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Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxyguanine analogs as prodrugs of an antiviral agent

Drug metabolism and disposition, 1994-03, Vol.22 (2), p.189

1994

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Induction of CYP3A enzymes in human and rat hepatocyte cultures

Biochemical Society transactions, 1994-05, Vol.22 (2), p.131S-131S

1994

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Metabolism of temelastine (SK&F 93944) in hepatocytes from rat, dog, cynomolgus monkey and man

Drug metabolism and disposition, 1990-03, Vol.18 (2), p.146

1990

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Cytochrome P450 maintenance and diazepam metabolism in cultured rat hepatocytes

Biochemical pharmacology, 1991-08, Vol.42 (6), p.1241-1245

1991

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The interaction of omeprazole with rat liver cytochrome P450 mediated monooxygenase reactions in vitro and in vivo

Biochemical pharmacology, 1988-04, Vol.37 (7), p.1407-1414

1988

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Antipyrine metabolism in cultured rat hepatocytes

Biochemical pharmacology, 1987-09, Vol.36 (18), p.3077-3081

1987

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The effect of cimetidine and ranitidine on paracetamol glucuronidation and sulphation in cultured rat hepatocytes

Biochemical pharmacology, 1985-05, Vol.34 (9), p.1415-1421

1985

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The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals

Drug metabolism and disposition, 1990-09, Vol.18 (5), p.613

1990

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Primary culture of rat hepatocytes in the presence of dimethyl sulphoxide: A system to investigate the regulation of cytochrome P450 IA

Biochemical pharmacology, 1991-12, Vol.42, p.S17-S25

1991

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The interaction of temelastine with cytochrome P450 mixed-function oxidase enzymes in vivo and in vitro

Biochemical pharmacology, 1989, Vol.38 (1), p.209-213

1989

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Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazone

Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9

Role of aldehyde oxidase in the in vitro conversion of famciclovir to penciclovir in human liver

In vitro identification of the P450 enzymes responsible for the metabolism of ropinirole

Disposition of ropinirole in animals and man

Characterization of the inhibition of P4501A2 by furafylline

Characterisation of the cytochrome P450 enzymes involved in the in vitro metabolism of granisetron

Determination of P4501A2 activity in human liver microsomes using [3-14C-methyl]caffeine

Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes

Crystal Structure of Human Cytochrome P450 2D6

Induction of cytochrome P4503A by the antiglucocorticoid mifepristone and a novel hypocholesterolaemic drug

Comparative drug metabolism of diazepam in hepatocytes isolated from man, rat, monkey and dog

Evidence that famciclovir (BRL 42810) and its associated metabolites do not inhibit the 6 beta-hydroxylation of testosterone in human liver microsomes

Diazepam metabolism in cultured hepatocytes from rat, rabbit, dog, guinea pig, and man

Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxy-guanine analogues as prodrugs of an antiviral agent

Use of rat and human in vitro systems to assess the effectiveness and enzymology of deoxyguanine analogs as prodrugs of an antiviral agent

Induction of CYP3A enzymes in human and rat hepatocyte cultures

Metabolism of temelastine (SK&F 93944) in hepatocytes from rat, dog, cynomolgus monkey and man

Cytochrome P450 maintenance and diazepam metabolism in cultured rat hepatocytes

The interaction of omeprazole with rat liver cytochrome P450 mediated monooxygenase reactions in vitro and in vivo

Antipyrine metabolism in cultured rat hepatocytes

The effect of cimetidine and ranitidine on paracetamol glucuronidation and sulphation in cultured rat hepatocytes

The disposition of 2-cyano-1-methyl 3-(4-(4-methyl-6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)phenyl)guanidine in animals

Primary culture of rat hepatocytes in the presence of dimethyl sulphoxide: A system to investigate the regulation of cytochrome P450 IA

The interaction of temelastine with cytochrome P450 mixed-function oxidase enzymes in vivo and in vitro

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