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Antagonists selective for NMDA receptors containing the NR2B subunit

Current pharmaceutical design, 1999-05, Vol.5 (5), p.381-404

1999

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Atropisomeric quinazolin-4-one derivatives are potent noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (2), p.177-181

2001

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Equilibration of the Oxidative Addition Product of Tetrakis(triphenylphosphine)palladium and Electron-Rich Aryl Halides Leads to Product Scrambling in the Stille Reaction

Journal of organic chemistry, 1995-01, Vol.60 (1), p.12-13

1995

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Functional characterization of CP-465,022, a selective, noncompetitive AMPA receptor antagonist

Neuropharmacology, 2002-02, Vol.42 (2), p.143-153

2002

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(1S,2S)-1-(4-Hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: A Potent New Neuroprotectant Which Blocks N-Methyl-D-Aspartate Responses

Journal of medicinal chemistry, 1995-08, Vol.38 (16), p.3138-3145

1995

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Quinazolin-4-one α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonists: Structure−Activity Relationship of the C-2 Side Chain Tether

Journal of medicinal chemistry, 2001-05, Vol.44 (11), p.1710-1717

2001

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CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents

Neuropharmacology, 2000-06, Vol.39 (7), p.1147-1155

2000

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Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists

Bioorganic & medicinal chemistry letters, 2000-06, Vol.10 (11), p.1203-1205

2000

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Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82,0715 on hippocampal cells in culture

The Journal of pharmacology and experimental therapeutics, 1992-02, Vol.260 (2), p.925

1992

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(3R,4S)-3-[4-(4-Fluorophenyl)-4-hydroxypiperidin-1-yl]chroman-4,7-diol: A Conformationally Restricted Analogue of the NR2B Subtype-Selective NMDA Antagonist (1S,2S)-1-(4-Hydroxyphenyl)-2- (4-hydroxy-4-phenylpiperidino)-1-propanol

Journal of medicinal chemistry, 1998-03, Vol.41 (7), p.1172-1184

1998

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Synthesis, structure, and properties of pentathiepins

Journal of the American Chemical Society, 1985-06, Vol.107 (13), p.3871-3879

1985

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Silylstannanes in organic synthesis. Scope and limitation of palladium-catalyzed reaction with acetylenes

Journal of organic chemistry, 1986-09, Vol.51 (19), p.3561-3566

1986

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CP-465,022, a selective noncompetitive AMPA receptor antagonist, blocks AMPA receptors but is not neuroprotective in vivo

Stroke (1970), 2003, Vol.34 (1), p.171-176

2003

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Characterization of the binding site for a novel class of noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists

Molecular pharmacology, 2000-12, Vol.58 (6), p.1310-1317

2000

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Electronic structure calculations of 1,3-dipolar cycloadditions using density functional and Hartree-Fock methods

International journal of quantum chemistry, 1994-02, Vol.49 (4), p.511-526

1994

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Benzopentathiepins: synthesis via thermolysis of benzothiadiazoles with sulfur

Journal of organic chemistry, 1984-04, Vol.49 (7), p.1221-1224

1984

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Synthesis, structures, and conformation dynamics of pyrazolotetrathiepins and related compounds studied by x-ray crystallography, dynamic NMR, and molecular orbital calculations

Journal of organic chemistry, 1987-06, Vol.52 (12), p.2411-2420

1987

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Separation of α1 adrenergic and N-methyl-D-aspartate antagonist activity in a series of ifenprodil compounds

Journal of medicinal chemistry, 1991-10, Vol.34 (10), p.3085-3090

1991

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A unified approach to systematic isosteric substitution for acidic groups and application to NMDA antagonists related to 2-amino-7-phosphonoheptanoate

Journal of medicinal chemistry, 1990-03, Vol.33 (3), p.1077-1083

1990

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A short synthesis of GYKI 52466

Bioorganic & medicinal chemistry letters, 1993-10, Vol.3 (10), p.1991-1992

1993

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Synthesis of high-specific activity tritium and optically pure [14C]CP-101,606. Enantioselective crystallization of a radiochemically racemic mixture

Journal of labelled compounds & radiopharmaceuticals, 1997-12, Vol.39 (12), p.973-985

1997

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alpha.-Nitroarylation of ketones and esters: an exceptionally facile synthesis of indoles, 2-indolinones and arylacetic acids

Journal of organic chemistry, 1986-05, Vol.51 (10), p.1704-1712

1986

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Synthesis and chemistry of 2-(arylthio)oxazolines

Journal of organic chemistry, 1983-07, Vol.48 (15), p.2610-2613

Chenard, B. L

1983

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Pyrazolothiadiazoles from 3-aminopyrazoles: the hetero-Herz reaction

Journal of organic chemistry, 1984-04, Vol.49 (7), p.1224-1227

Chenard, B. L

1984

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3-Stannyl-1-silyloxycyclohex-1-enes: Synthetic equivalents for ketone α, β-dianions

Tetrahedron letters, 1986, Vol.27 (25), p.2805-2808

Chenard, B.L.

1986

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Antagonists selective for NMDA receptors containing the NR2B subunit

Atropisomeric quinazolin-4-one derivatives are potent noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists

Equilibration of the Oxidative Addition Product of Tetrakis(triphenylphosphine)palladium and Electron-Rich Aryl Halides Leads to Product Scrambling in the Stille Reaction

Functional characterization of CP-465,022, a selective, noncompetitive AMPA receptor antagonist

(1S,2S)-1-(4-Hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol: A Potent New Neuroprotectant Which Blocks N-Methyl-D-Aspartate Responses

Quinazolin-4-one α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonists: Structure−Activity Relationship of the C-2 Side Chain Tether

CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents

Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists

Neuroprotective effects of the N-methyl-D-aspartate receptor antagonists ifenprodil and SL-82,0715 on hippocampal cells in culture

(3R,4S)-3-[4-(4-Fluorophenyl)-4-hydroxypiperidin-1-yl]chroman-4,7-diol: A Conformationally Restricted Analogue of the NR2B Subtype-Selective NMDA Antagonist (1S,2S)-1-(4-Hydroxyphenyl)-2- (4-hydroxy-4-phenylpiperidino)-1-propanol

Synthesis, structure, and properties of pentathiepins

Silylstannanes in organic synthesis. Scope and limitation of palladium-catalyzed reaction with acetylenes

CP-465,022, a selective noncompetitive AMPA receptor antagonist, blocks AMPA receptors but is not neuroprotective in vivo

Characterization of the binding site for a novel class of noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists

Electronic structure calculations of 1,3-dipolar cycloadditions using density functional and Hartree-Fock methods

Benzopentathiepins: synthesis via thermolysis of benzothiadiazoles with sulfur

Synthesis, structures, and conformation dynamics of pyrazolotetrathiepins and related compounds studied by x-ray crystallography, dynamic NMR, and molecular orbital calculations

Separation of α1 adrenergic and N-methyl-D-aspartate antagonist activity in a series of ifenprodil compounds

A unified approach to systematic isosteric substitution for acidic groups and application to NMDA antagonists related to 2-amino-7-phosphonoheptanoate

A short synthesis of GYKI 52466

Synthesis of high-specific activity tritium and optically pure [14C]CP-101,606. Enantioselective crystallization of a radiochemically racemic mixture

alpha.-Nitroarylation of ketones and esters: an exceptionally facile synthesis of indoles, 2-indolinones and arylacetic acids

Synthesis and chemistry of 2-(arylthio)oxazolines

Pyrazolothiadiazoles from 3-aminopyrazoles: the hetero-Herz reaction

3-Stannyl-1-silyloxycyclohex-1-enes: Synthetic equivalents for ketone α, β-dianions

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