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The quest for supernatural products: the impact of total synthesis in complex natural products medicinal chemistry

Natural product reports, 2020-11, Vol.37 (11), p.1511-1531

2020

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Synthesis, Characterization, and Cycloaddition Reactivity of a Monocyclic Aromatic 1,2,3,5-Tetrazine

Journal of the American Chemical Society, 2019-10, Vol.141 (41), p.16388-16397

2019

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Corona[5]arenes Accessed by a Macrocycle‐to‐Macrocycle Transformation Route and a One‐Pot Three‐Component Reaction

Angewandte Chemie International Edition, 2017-06, Vol.56 (25), p.7151-7155

International ed. in English, 2017

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Total flavones of Rhododendron simsii Planch flower protect rat hippocampal neuron from hypoxia-reoxygenation injury via activation of BKCa channel

Journal of pharmacy and pharmacology, 2020-01, Vol.72 (1), p.111-120

2020

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Urotensin-ⅡReceptor Antagonist SB-710411 Protects Rat Heart against Ischemia-Reperfusion Injury via RhoA/ROCK Pathway

PloS one, 2016-01, Vol.11 (1), p.e0146094-e0146094

2016

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Total Synthesis and Stereochemical Assignment of Streptide

Journal of the American Chemical Society, 2019-10, Vol.141 (43), p.17361-17369

2019

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Anfibatide protects against rat cerebral ischemia/reperfusion injury via TLR4/JNK/caspase-3 pathway

European journal of pharmacology, 2017-07, Vol.807, p.127-137

2017

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Total flavones of Rhododendron simsii Planch flower protect isolated rat heart from ischaemia‐reperfusion injury and its mechanism of UTR‐RhoA‐ROCK pathway inhibition

Journal of pharmacy and pharmacology, 2018-12, Vol.70 (12), p.1713-1722

2018

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Endothelium‐derived hydrogen sulfide acts as a hyperpolarizing factor and exerts neuroprotective effects via activation of large‐conductance Ca2+‐activated K+ channels

British journal of pharmacology, 2021-10, Vol.178 (20), p.4155-4175

2021

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Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons

Journal of neuroinflammation, 2015-12, Vol.12 (244), p.246-246, Article 246

2015

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Total Flavone of Rhododendron Improves Cerebral Ischemia Injury by Activating Vascular TRPV4 to Induce Endothelium-Derived Hyperpolarizing Factor-Mediated Responses

Evidence-based complementary and alternative medicine, 2018-01, Vol.2018 (1), p.8919867-8919867

2018

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Dietary aflatoxin B1 induces abnormal deposition of melanin in the corium layer of the chicken shank possibly via promoting the expression of melanin synthesis-related genes

Journal of Integrative Agriculture, 2023-06, Vol.22 (6), p.1847-1856

2023

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Acetylcholine- and Sodium Hydrosulfide–Induced Endothelium-Dependent Relaxation and Hyperpolarization in Cerebral Vessels of Global Cerebral Ischemia–Reperfusion Rat

Journal of Pharmacological Sciences, 2013/04/20, Vol.121(4), pp.318-326

2013

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Maxamycins: Durable Antibiotics Derived by Rational Redesign of Vancomycin

Accounts of chemical research, 2020-11, Vol.53 (11), p.2587-2599

2020

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Double-diffusive Marangoni convection in a rectangular cavity: Onset of convection

Physics of fluids (1994), 2010-03, Vol.22 (3), p.034106-034106-13

2010

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Robust Partially Strong Tracking Extended Consider Kalman Filtering for INS/GNSS Integrated Navigation

IEEE access, 2019, Vol.7, p.151230-151238

2019

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3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/ROCK pathway

American Journal of Physiology: Cell Physiology, 2020-10, Vol.319 (4), p.C720-C733

2020

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Role of CSE-Produced H2S on Cerebrovascular Relaxation via RhoA-ROCK Inhibition and Cerebral Ischemia-Reperfusion Injury in Mice

ACS chemical neuroscience, 2019-03, Vol.10 (3), p.1565-1574

2019

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Mechanistic Insights into the Reaction of Amidines with 1,2,3-Triazines and 1,2,3,5-Tetrazines

Journal of the American Chemical Society, 2022-06, Vol.144 (24), p.10921-10928

2022

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1,2,3,5-Tetrazines: A General Synthesis, Cycloaddition Scope, and Fundamental Reactivity Patterns

Journal of organic chemistry, 2022-12, Vol.87 (24), p.16829-16846

2022

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Particular Levels of Odors Released by Virgin Females Attract Conspecific Males of the Funnel-Web Spider Allagelena difficilis

Journal of chemical ecology, 2018-10, Vol.44 (10), p.905-914

2018

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miR‑133b‑5p contributes to hypoxic preconditioning‑mediated cardioprotection by inhibiting the activation of caspase‑8 and caspase-3 in cardiomyocytes

Molecular medicine reports, 2018-05, Vol.17 (5), p.7097-7104

2018

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Involvement of ubiquitin proteasome system in protective mechanisms of Puerarin to MPP +-elicited apoptosis

Neuroscience research, 2009, Vol.63 (1), p.52-58

2009

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Protective Effect and Mechanism of Total Flavones from Rhododendron simsii Planch on Endothelium-Dependent Dilatation and Hyperpolarization in Cerebral Ischemia-Reperfusion and Correlation to Hydrogen Sulphide Release in Rats

Evidence-based complementary and alternative medicine, 2014-01, Vol.2014 (1), p.904019-904019

2014

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Exploration of the site-specific nature and generalizability of a trimethylammonium salt modification on vancomycin: A-ring derivatives

Tetrahedron, 2019-06, Vol.75 (24), p.3160-3165

2019

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The quest for supernatural products: the impact of total synthesis in complex natural products medicinal chemistry

Synthesis, Characterization, and Cycloaddition Reactivity of a Monocyclic Aromatic 1,2,3,5-Tetrazine

Corona[5]arenes Accessed by a Macrocycle‐to‐Macrocycle Transformation Route and a One‐Pot Three‐Component Reaction

Total flavones of Rhododendron simsii Planch flower protect rat hippocampal neuron from hypoxia-reoxygenation injury via activation of BKCa channel

Urotensin-ⅡReceptor Antagonist SB-710411 Protects Rat Heart against Ischemia-Reperfusion Injury via RhoA/ROCK Pathway

Total Synthesis and Stereochemical Assignment of Streptide

Anfibatide protects against rat cerebral ischemia/reperfusion injury via TLR4/JNK/caspase-3 pathway

Total flavones of Rhododendron simsii Planch flower protect isolated rat heart from ischaemia‐reperfusion injury and its mechanism of UTR‐RhoA‐ROCK pathway inhibition

Endothelium‐derived hydrogen sulfide acts as a hyperpolarizing factor and exerts neuroprotective effects via activation of large‐conductance Ca2+‐activated K+ channels

Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons

Total Flavone of Rhododendron Improves Cerebral Ischemia Injury by Activating Vascular TRPV4 to Induce Endothelium-Derived Hyperpolarizing Factor-Mediated Responses

Dietary aflatoxin B1 induces abnormal deposition of melanin in the corium layer of the chicken shank possibly via promoting the expression of melanin synthesis-related genes

Acetylcholine- and Sodium Hydrosulfide–Induced Endothelium-Dependent Relaxation and Hyperpolarization in Cerebral Vessels of Global Cerebral Ischemia–Reperfusion Rat

Maxamycins: Durable Antibiotics Derived by Rational Redesign of Vancomycin

Double-diffusive Marangoni convection in a rectangular cavity: Onset of convection

Robust Partially Strong Tracking Extended Consider Kalman Filtering for INS/GNSS Integrated Navigation

3-Mercaptopyruvate sulfurtransferase/hydrogen sulfide protects cerebral endothelial cells against oxygen-glucose deprivation/reoxygenation-induced injury via mitoprotection and inhibition of the RhoA/ROCK pathway

Role of CSE-Produced H2S on Cerebrovascular Relaxation via RhoA-ROCK Inhibition and Cerebral Ischemia-Reperfusion Injury in Mice

Mechanistic Insights into the Reaction of Amidines with 1,2,3-Triazines and 1,2,3,5-Tetrazines

1,2,3,5-Tetrazines: A General Synthesis, Cycloaddition Scope, and Fundamental Reactivity Patterns

Particular Levels of Odors Released by Virgin Females Attract Conspecific Males of the Funnel-Web Spider Allagelena difficilis

miR‑133b‑5p contributes to hypoxic preconditioning‑mediated cardioprotection by inhibiting the activation of caspase‑8 and caspase-3 in cardiomyocytes

Involvement of ubiquitin proteasome system in protective mechanisms of Puerarin to MPP +-elicited apoptosis

Protective Effect and Mechanism of Total Flavones from Rhododendron simsii Planch on Endothelium-Dependent Dilatation and Hyperpolarization in Cerebral Ischemia-Reperfusion and Correlation to Hydrogen Sulphide Release in Rats

Exploration of the site-specific nature and generalizability of a trimethylammonium salt modification on vancomycin: A-ring derivatives

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