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A phase I study of the WT2725 dosing emulsion in patients with advanced malignancies

Scientific reports, 2021-11, Vol.11 (1), p.22355-11, Article 22355

2021

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Evaluation of OCT2‐mediated drug–drug interactions between ulotaront and metformin in subjects with schizophrenia

Pharmacology research & perspectives, 2024-04, Vol.12 (2), p.e1191-n/a

2024

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Validation of a sensitive and specific LC–MS/MS method and application to evaluate the systemic exposure and bioavailability of glycopyrrolate via different drug delivery approaches/devices

Biomedical chromatography, 2020-09, Vol.34 (9), p.e4899-n/a

2020

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Comparative Bioequivalence of Tablet and Capsule Formulations of Ulotaront and the Effect of Food on the Pharmacokinetics of the Tablet Form in Humans

Neurology and therapy, 2023-06, Vol.12 (3), p.815-832

2023

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A sensitive liquid chromatography-tandem mass spectrometry method for quantitative determination of dasotraline in human plasma and its clinical application

Journal of pharmaceutical and biomedical analysis, 2020-11, Vol.191, p.113611, Article 113611

2020

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In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT1A Receptor Agonist for the Treatment of Schizophrenia

Pharmaceutical research, 2022-05, Vol.39 (5), p.837-850

2022

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A sensitive LC-MS/MS method for simultaneous quantification of ulotaront and its N-desmethyl metabolite in human plasma and application to a clinical study

Journal of pharmaceutical and biomedical analysis, 2022-01, Vol.207, p.114404-114404, Article 114404

2022

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Effects of St. John's Wort (Hypericum perforatum) on Tacrolimus Pharmacokinetics in Healthy Volunteers

Journal of clinical pharmacology, 2004-01, Vol.44 (1), p.89-94

2004

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LC-MS/MS simultaneous quantification of apomorphine and its major metabolites in human plasma: Application to clinical comparative bioavailability evaluation for the apomorphine sublingual film and a subcutaneous product

Journal of pharmaceutical and biomedical analysis, 2020-10, Vol.190, p.113493, Article 113493

2020

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Absorption, distribution, metabolism, and excretion of [14C]‐dasotraline in humans

Pharmacology research & perspectives, 2017-02, Vol.5 (1), p.e00281-n/a

2017

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Exploratory Biomarker Study of the Triple Reuptake Inhibitor SEP‐432 Compared to the Dual Reuptake Inhibitor Duloxetine in Healthy Normal Subjects

CNS neuroscience & therapeutics, 2016-05, Vol.22 (5), p.404-412

2016

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A Phase I, Open-Label, Fixed Sequence Study to Investigate the Effect of Cytochrome P450 2D6 Inhibition on the Pharmacokinetics of Ulotaront in Healthy Subjects

Clinical pharmacokinetics, 2023-12, Vol.62 (12), p.1755-1763

2023

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An ultrasensitive LC–MS/MS method and application to clinical dose-range finding for glycopyrrolate via an e-Nebulizer

Bioanalysis, 2021-06, Vol.13 (12), p.959-968

2021

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Simultaneous determination of three isomeric metabolites of tacrolimus (FK506) in human whole blood and plasma using high performance liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2006-01, Vol.830 (2), p.330-341

2006

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Direct Quantitation of D-serine in Human Plasma by Enantioselective Liquid Chromatography with Tandem Mass Spectrometry and its Application to a Clinical Study

Journal of applied bioanalysis, 2019-04, Vol.5 (2), p.20-33

2019

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Automatic Supported Liquid Extraction (SLE) Coupled with HILIC-MS/MS: An Application to Method Development and Validation of Erlotinib in Human Plasma

Pharmaceutics, 2010-04, Vol.2 (2), p.105-118

2010

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Ultrafast liquid chromatography/tandem mass spectrometry bioanalysis of polar analytes using packed silica columns

Rapid communications in mass spectrometry, 2002-01, Vol.16 (17), p.1613-1621

2002

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An Ultrasensitive LC-APPI-MS/MS Method for Simultaneous Determination of Ciclesonide and Active Metabolite Desisobutyryl-Ciclesonide in Human Serum and Its Application to a Clinical Study

The journal of applied laboratory medicine, 2020-01, Vol.5 (1), p.41-53

2020

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Conformations of Gas-Phase Lysozyme Ions Produced from Two Different Solution Conformations

Analytical chemistry (Washington), 2003-03, Vol.75 (6), p.1325-1330

2003

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Collision cross sections of myoglobin and cytochrome c ions with Ne, Ar, and Kr

Journal of the American Society for Mass Spectrometry, 1997-07, Vol.8 (7), p.681-687

1997

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Investigation of Human in vivo Metabolism of SEP-227900 Using the Samples from First-in-Human Study by LC-HRMS/UV and NMR

Drug Metabolism and Bioanalysis Letters, 2022, Vol.15 (1), p.38-50

2022

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In vivo metabolism for the hydroxylation of FK778 to the metabolite M3 in humans studied by enantioselective liquid chromatography/tandem mass spectrometry

Rapid communications in mass spectrometry, 2005-01, Vol.19 (18), p.2681-2688

2005

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Simultaneous determination of theophylline, tolbutamide, mephenytoin, debrisoquin, and dapsone in human plasma using high-speed gradient liquid chromatography/tandem mass spectrometry on a silica-based monolithic column

Journal of separation science, 2003-11, Vol.26 (17), p.1509-1519

2003

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Quantification of 6-deoxy-6-demethyl-4-dedimethylaminotetracycline (COL-3) in human plasma using liquid chromatography coupled with electrospray ionization tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2003-08, Vol.794 (1), p.77-88

2003

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Simultaneous development of six LC–MS–MS methods for the determination of multiple analytes in human plasma

Journal of pharmaceutical and biomedical analysis, 2002-06, Vol.28 (6), p.1115-1126

2002

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A phase I study of the WT2725 dosing emulsion in patients with advanced malignancies

Evaluation of OCT2‐mediated drug–drug interactions between ulotaront and metformin in subjects with schizophrenia

Validation of a sensitive and specific LC–MS/MS method and application to evaluate the systemic exposure and bioavailability of glycopyrrolate via different drug delivery approaches/devices

Comparative Bioequivalence of Tablet and Capsule Formulations of Ulotaront and the Effect of Food on the Pharmacokinetics of the Tablet Form in Humans

A sensitive liquid chromatography-tandem mass spectrometry method for quantitative determination of dasotraline in human plasma and its clinical application

In Vitro ADME and Preclinical Pharmacokinetics of Ulotaront, a TAAR1/5-HT1A Receptor Agonist for the Treatment of Schizophrenia

A sensitive LC-MS/MS method for simultaneous quantification of ulotaront and its N-desmethyl metabolite in human plasma and application to a clinical study

Effects of St. John's Wort (Hypericum perforatum) on Tacrolimus Pharmacokinetics in Healthy Volunteers

LC-MS/MS simultaneous quantification of apomorphine and its major metabolites in human plasma: Application to clinical comparative bioavailability evaluation for the apomorphine sublingual film and a subcutaneous product

Absorption, distribution, metabolism, and excretion of [14C]‐dasotraline in humans

Exploratory Biomarker Study of the Triple Reuptake Inhibitor SEP‐432 Compared to the Dual Reuptake Inhibitor Duloxetine in Healthy Normal Subjects

A Phase I, Open-Label, Fixed Sequence Study to Investigate the Effect of Cytochrome P450 2D6 Inhibition on the Pharmacokinetics of Ulotaront in Healthy Subjects

An ultrasensitive LC–MS/MS method and application to clinical dose-range finding for glycopyrrolate via an e-Nebulizer

Simultaneous determination of three isomeric metabolites of tacrolimus (FK506) in human whole blood and plasma using high performance liquid chromatography–tandem mass spectrometry

Direct Quantitation of D-serine in Human Plasma by Enantioselective Liquid Chromatography with Tandem Mass Spectrometry and its Application to a Clinical Study

Automatic Supported Liquid Extraction (SLE) Coupled with HILIC-MS/MS: An Application to Method Development and Validation of Erlotinib in Human Plasma

Ultrafast liquid chromatography/tandem mass spectrometry bioanalysis of polar analytes using packed silica columns

An Ultrasensitive LC-APPI-MS/MS Method for Simultaneous Determination of Ciclesonide and Active Metabolite Desisobutyryl-Ciclesonide in Human Serum and Its Application to a Clinical Study

Conformations of Gas-Phase Lysozyme Ions Produced from Two Different Solution Conformations

Collision cross sections of myoglobin and cytochrome c ions with Ne, Ar, and Kr

Investigation of Human in vivo Metabolism of SEP-227900 Using the Samples from First-in-Human Study by LC-HRMS/UV and NMR

In vivo metabolism for the hydroxylation of FK778 to the metabolite M3 in humans studied by enantioselective liquid chromatography/tandem mass spectrometry

Simultaneous determination of theophylline, tolbutamide, mephenytoin, debrisoquin, and dapsone in human plasma using high-speed gradient liquid chromatography/tandem mass spectrometry on a silica-based monolithic column

Quantification of 6-deoxy-6-demethyl-4-dedimethylaminotetracycline (COL-3) in human plasma using liquid chromatography coupled with electrospray ionization tandem mass spectrometry

Simultaneous development of six LC–MS–MS methods for the determination of multiple analytes in human plasma

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