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The Anti-inflammatory TIPE2 Is an Inhibitor of the Oncogenic Ras

Molecular cell, 2012-03, Vol.45 (5), p.610-618

2012

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Regulation of inflammation and tumorigenesis by the TIPE family of phospholipid transfer proteins

Cellular & molecular immunology, 2017-06, Vol.14 (6), p.482-487

2017

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Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor

Frontiers in immunology, 2019-06, Vol.10, p.1399-1399

2019

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Inhibition of c-Rel expression in myeloid and lymphoid cells with distearoyl -phosphatidylserine (DSPS) liposomal nanoparticles encapsulating therapeutic siRNA

PloS one, 2022-12, Vol.17 (12), p.e0276905

2022

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Negative Immune Regulator TIPE2 Promotes M2 Macrophage Differentiation through the Activation of PI3K-AKT Signaling Pathway

PloS one, 2017-01, Vol.12 (1), p.e0170666-e0170666

2017

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TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer

Cancer cell, 2014-10, Vol.26 (4), p.465-478

2014

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The microRNA-21–PDCD4 axis prevents type 1 diabetes by blocking pancreatic β cell death

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (29), p.12030-12035

2011

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HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8 + T-cell infiltration into tumors

Nature communications, 2022-07, Vol.13 (1), p.4078-4078, Article 4078

2022

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Myeloid-Derived Suppressor Cell Differentiation in Cancer: Transcriptional Regulators and Enhanceosome-Mediated Mechanisms

Frontiers in immunology, 2021-01, Vol.11, p.619253

2021

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CAR-Macrophages and CAR-T Cells Synergistically Kill Tumor Cells In Vitro

Cells (Basel, Switzerland), 2022-11, Vol.11 (22), p.3692

2022

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Monocytes in Tumorigenesis and Tumor Immunotherapy

Cells (Basel, Switzerland), 2023-06, Vol.12 (13), p.1673

2023

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TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (38), p.15413-15418

2012

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Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages

Cell reports (Cambridge), 2020-06, Vol.31 (13), p.107825-107825, Article 107825

2020

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c-Rel Is a Myeloid Checkpoint for Cancer Immunotherapy

Nature cancer, 2020-05, Vol.1 (5), p.507-517

2020

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An Integrated Deep Learning and Molecular Dynamics Simulation-Based Screening Pipeline Identifies Inhibitors of a New Cancer Drug Target TIPE2

Frontiers in pharmacology, 2021-11, Vol.12, p.772296-772296

2021

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Treatment of acetaminophen-induced liver failure by blocking the death checkpoint protein TRAIL

Biochimica et biophysica acta. Molecular basis of disease, 2020-01, Vol.1866 (1), p.165583, Article 165583

2020

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Silencing c‐Rel in macrophages dampens Th1 and Th17 immune responses and alleviates experimental autoimmune encephalomyelitis in mice

Immunology and cell biology, 2017-08, Vol.95 (7), p.593-600

2017

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TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis

Cell death & disease, 2022-04, Vol.13 (4), p.311-10, Article 311

2022

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TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling

Nature communications, 2020-05, Vol.11 (1), p.2591-20, Article 2591

2020

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Nuclear factor-κB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome

Proceedings of the National Academy of Sciences - PNAS, 2012-08, Vol.109 (35), p.14140-14145

2012

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Small-Molecule Inhibitors of TIPE3 Protein Identified through Deep Learning Suppress Cancer Cell Growth In Vitro

Cells (Basel, Switzerland), 2024-05, Vol.13 (9), p.771

2024

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Peritoneal resident macrophages in tumor metastasis and immunotherapy

Frontiers in cell and developmental biology, 2022-08, Vol.10, p.948952-948952

2022

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Essential Roles of c-Rel in TLR-Induced IL-23 p19 Gene Expression in Dendritic Cells

Journal of Immunology, 2007-01, Vol.178 (1), p.186-191

2007

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Translational Regulation of Autoimmune Inflammation and Lymphoma Genesis by Programmed Cell Death 4

Journal of Immunology, 2006-12, Vol.177 (11), p.8095-8102

2006

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In Silico Study of Potential Small Molecule TIPE2 Inhibitors for the Treatment of Cancer

Sci, 2023-10, Vol.5 (4), p.39

2023

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The Anti-inflammatory TIPE2 Is an Inhibitor of the Oncogenic Ras

Regulation of inflammation and tumorigenesis by the TIPE family of phospholipid transfer proteins

Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor

Inhibition of c-Rel expression in myeloid and lymphoid cells with distearoyl -phosphatidylserine (DSPS) liposomal nanoparticles encapsulating therapeutic siRNA

Negative Immune Regulator TIPE2 Promotes M2 Macrophage Differentiation through the Activation of PI3K-AKT Signaling Pathway

TIPE3 Is the Transfer Protein of Lipid Second Messengers that Promote Cancer

The microRNA-21–PDCD4 axis prevents type 1 diabetes by blocking pancreatic β cell death

HRS phosphorylation drives immunosuppressive exosome secretion and restricts CD8 + T-cell infiltration into tumors

Myeloid-Derived Suppressor Cell Differentiation in Cancer: Transcriptional Regulators and Enhanceosome-Mediated Mechanisms

CAR-Macrophages and CAR-T Cells Synergistically Kill Tumor Cells In Vitro

Monocytes in Tumorigenesis and Tumor Immunotherapy

TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection

Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages

c-Rel Is a Myeloid Checkpoint for Cancer Immunotherapy

An Integrated Deep Learning and Molecular Dynamics Simulation-Based Screening Pipeline Identifies Inhibitors of a New Cancer Drug Target TIPE2

Treatment of acetaminophen-induced liver failure by blocking the death checkpoint protein TRAIL

Silencing c‐Rel in macrophages dampens Th1 and Th17 immune responses and alleviates experimental autoimmune encephalomyelitis in mice

TNFAIP8 protein functions as a tumor suppressor in inflammation-associated colorectal tumorigenesis

TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling

Nuclear factor-κB binding motifs specify Toll-like receptor-induced gene repression through an inducible repressosome

Small-Molecule Inhibitors of TIPE3 Protein Identified through Deep Learning Suppress Cancer Cell Growth In Vitro

Peritoneal resident macrophages in tumor metastasis and immunotherapy

Essential Roles of c-Rel in TLR-Induced IL-23 p19 Gene Expression in Dendritic Cells

Translational Regulation of Autoimmune Inflammation and Lymphoma Genesis by Programmed Cell Death 4

In Silico Study of Potential Small Molecule TIPE2 Inhibitors for the Treatment of Cancer

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