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Role of the cGAS–STING pathway in cancer development and oncotherapeutic approaches

EMBO reports, 2018-12, Vol.19 (12), p.n/a

2018

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The human CST complex is a terminator of telomerase activity

Nature (London), 2012-08, Vol.488 (7412), p.540-544

2012

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Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway

Nature structural & molecular biology, 2017-12, Vol.24 (12), p.1124-1131

2017

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Molecular basis of telomere syndrome caused by CTC1 mutations

Genes & development, 2013-10, Vol.27 (19), p.2099-2108

2013

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Peri‐treatment adverse events of primary mediastinal non‐seminomatous germ cell tumors

Pediatric blood & cancer, 2022-08, Vol.69 (8), p.e29781-n/a

2022

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XPF activates break-induced telomere synthesis

Nature communications, 2022-10, Vol.13 (1), p.5781-5781, Article 5781

2022

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Incorporating innovative B‐cell targeting therapeutics into a combined‐modality bridging approach followed by timely consolidative haploidentical transplantation to salvage a pediatric patient with relapsed/refractory diffuse large B‐cell lymphoma

Pediatric blood & cancer, 2024-11, Vol.71 (11), p.e31289-n/a

2024

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Phosphorylation of TPP1 regulates cell cycle-dependent telomerase recruitment

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (14), p.5457-5462

2013

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Ends end it via mitochondria: A telomere-dependent tumor suppressive mechanism acts during replicative crisis

Molecular cell, 2023-04, Vol.83 (7), p.1027-1029

2023

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Telomere Maintenance through Spatial Control of Telomeric Proteins

Molecular and Cellular Biology, 2007-08, Vol.27 (16), p.5898-5909

2007

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Mitochondrial Localization of Telomeric Protein TIN2 Links Telomere Regulation to Metabolic Control

Molecular cell, 2012-09, Vol.47 (6), p.839-850

2012

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Evolution of Graves' Disease during Immune Reconstitution following Nonmyeloablative Haploidentical Peripheral Blood Stem Cell Transplantation in a Boy Carrying Germline SAMD9L and FLT3 Variants

International journal of molecular sciences, 2022-08, Vol.23 (16), p.9494

2022

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Complications for a Hoyeraal-Hreidarsson Syndrome Patient with a Germline DKC1 A353V Variant Undergoing Unrelated Peripheral Blood Stem Cell Transplantation

International journal of molecular sciences, 2019-07, Vol.20 (13), p.3261

2019

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Anti-Thymocyte Globulin (ATG)-Free Nonmyeloablative Haploidentical PBSCT Plus Post-Transplantation Cyclophosphamide Is a Safe and Efficient Treatment Approach for Pediatric Acquired Aplastic Anemia

International journal of molecular sciences, 2022-12, Vol.23 (23), p.15192

2022

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Elp1 facilitates RAD51-mediated homologous recombination repair via translational regulation

Journal of biomedical science, 2021-11, Vol.28 (1), p.1-81, Article 81

2021

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TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs

Nature structural & molecular biology, 2009-04, Vol.16 (4), p.372-379

2009

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A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres

International journal of molecular sciences, 2021-03, Vol.22 (5), p.2365

2021

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Tethering CST to the telomerase catalytic core—the p50 linchpin

Structure (London), 2022-12, Vol.30 (12), p.1563-1564

2022

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No DDRama at chromosome ends: TRF2 takes centre stage

Trends in biochemical sciences (Amsterdam. Regular ed.), 2015-05, Vol.40 (5), p.275-285

2015

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Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways

Molecular and Cellular Biology, 2003-10, Vol.23 (20), p.7108-7121

2003

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Regulation of Androgen Receptor Activity by the Nuclear Receptor Corepressor SMRT

The Journal of biological chemistry, 2003-02, Vol.278 (7), p.5052-5061

2003

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CST for the grand finale of telomere replication

Nucleus (Austin, Tex.), 2013-07, Vol.4 (4), p.277-282

2013

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Analysis of structure–activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors

Bioorganic & medicinal chemistry, 2023-11, Vol.95, p.117502-117502, Article 117502

2023

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Regulation and Binding of Pregnane X Receptor by Nuclear Receptor Corepressor Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT)

Molecular pharmacology, 2006-01, Vol.69 (1), p.99-108

2006

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Role of the cGAS–STING pathway in cancer development and oncotherapeutic approaches

The human CST complex is a terminator of telomerase activity

Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway

Molecular basis of telomere syndrome caused by CTC1 mutations

Peri‐treatment adverse events of primary mediastinal non‐seminomatous germ cell tumors

XPF activates break-induced telomere synthesis

Incorporating innovative B‐cell targeting therapeutics into a combined‐modality bridging approach followed by timely consolidative haploidentical transplantation to salvage a pediatric patient with relapsed/refractory diffuse large B‐cell lymphoma

Long-term hematopoietic transfer of the anti-cancer and lifespan-extending capabilities of a genetically engineered blood system by transplantation of bone marrow mononuclear cells

Phosphorylation of TPP1 regulates cell cycle-dependent telomerase recruitment

Ends end it via mitochondria: A telomere-dependent tumor suppressive mechanism acts during replicative crisis

Telomere Maintenance through Spatial Control of Telomeric Proteins

Mitochondrial Localization of Telomeric Protein TIN2 Links Telomere Regulation to Metabolic Control

Evolution of Graves' Disease during Immune Reconstitution following Nonmyeloablative Haploidentical Peripheral Blood Stem Cell Transplantation in a Boy Carrying Germline SAMD9L and FLT3 Variants

Complications for a Hoyeraal-Hreidarsson Syndrome Patient with a Germline DKC1 A353V Variant Undergoing Unrelated Peripheral Blood Stem Cell Transplantation

Anti-Thymocyte Globulin (ATG)-Free Nonmyeloablative Haploidentical PBSCT Plus Post-Transplantation Cyclophosphamide Is a Safe and Efficient Treatment Approach for Pediatric Acquired Aplastic Anemia

Elp1 facilitates RAD51-mediated homologous recombination repair via translational regulation

TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs

A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres

Tethering CST to the telomerase catalytic core—the p50 linchpin

No DDRama at chromosome ends: TRF2 takes centre stage

Daxx Silencing Sensitizes Cells to Multiple Apoptotic Pathways

Regulation of Androgen Receptor Activity by the Nuclear Receptor Corepressor SMRT

CST for the grand finale of telomere replication

Analysis of structure–activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors

Regulation and Binding of Pregnane X Receptor by Nuclear Receptor Corepressor Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT)

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