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Use of dihydroxyacetone phosphate dependent aldolases in the synthesis of deoxyazasugars

Journal of organic chemistry, 1991-10, Vol.56 (22), p.6280-6289

1991

Volltextzugriff (PDF)

Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α2α

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1380-1400

2007

Volltextzugriff (PDF)

β-C-Mannosides as Selectin Inhibitors

Journal of medicinal chemistry, 2002-04, Vol.45 (8), p.1563-1566

2002

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Deoxyribose 5-phosphate aldolase as a catalyst in asymmetric aldol condensation

Journal of the American Chemical Society, 1992-01, Vol.114 (2), p.741-748

1992

Volltextzugriff (PDF)

Discovery of ecopladib, an indole inhibitor of cytosolic phospholipase A2α

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1380-1400

2007

Volltextzugriff (PDF)

Piperazine Sulfonamides as Potent, Selective, and Orally Available 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors with Efficacy in the Rat Cortisone-Induced Hyperinsulinemia Model

Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4068-4071

2008

Volltextzugriff (PDF)

Reactions of Functionalized Sulfonamides: Application to Lowering the Lipophilicity of Cytosolic Phospholipase A 2 α Inhibitors

Journal of medicinal chemistry, 2009-02, Vol.52 (4), p.1156-1171

2009

Volltextzugriff (PDF)

Enzymes in organic synthesis: synthesis of highly enantiomerically pure 1,2-epoxy aldehydes, epoxy alcohols, thiirane, aziridine, and glyceraldehyde 3-phosphate

Journal of organic chemistry, 1990-08, Vol.55 (16), p.4897-4901

1990

Volltextzugriff (PDF)

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2α : Optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Bioorganic & medicinal chemistry, 2008-02, Vol.16 (3), p.1345-1358

2008

Volltextzugriff (PDF)

Reactions of Functionalized Sulfonamides: Application to Lowering the Lipophilicity of Cytosolic Phospholipase A2α Inhibitors

Journal of medicinal chemistry, 2009-02, Vol.52 (4), p.1156-1171

2009

Volltextzugriff (PDF)

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A 2α: Optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Bioorganic & medicinal chemistry, 2008, Vol.16 (3), p.1345-1358

2008

Volltextzugriff (PDF)

Discovery of Ecopladib, an indole inhibitor of cytosolic phospholipase A2alpha

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1380-1400

2007

Volltextzugriff (PDF)

Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α 2 α

Journal of medicinal chemistry, 2007-03, Vol.50 (6), p.1380-1400

2007

Volltextzugriff (PDF)

Recombinant 2-Deoxyribose-5-phosphate Aldolase in Organic Synthesis: Use of Sequential Two-Substrate and Three-Substrate Aldol Reactions

Journal of the American Chemical Society, 1995-03, Vol.117 (12), p.3333-3339

1995

Volltextzugriff (PDF)

Palladium-mediated stereocontrolled reductive amination of azido sugars prepared from enzymic aldol condensation: a general approach to the synthesis of deoxy aza sugars

Journal of the American Chemical Society, 1991-08, Vol.113 (17), p.6678-6680

1991

Volltextzugriff (PDF)

Synthesis of C1-C8 and C9-C24 fragments of (−)-discodermolide: use of asymmetric alkylation and stereoselective aldol reactions

Tetrahedron letters, 1999-07, Vol.40 (30), p.5449-5453

1999

Volltextzugriff (PDF)

Use of dihydroxyacetone phosphate-dependent aldolases in the synthesis of deoxy aza sugars

Journal of organic chemistry, 1991-10, Vol.56 (22), p.6280-6289

1991

Volltextzugriff (PDF)

Enzymes for carbohydrate and peptide syntheses

Pure and applied chemistry, 1992-01, Vol.64 (8), p.1197-1202

1992

Volltextzugriff (PDF)

Palladium-mediated stereocontrolled reductive amination of azido sugars prepared from enzymatic aldol condensation : a general approach to the synthesis of deoxy aza sugars

Journal of the American Chemical Society, 1991-08, Vol.113 (17), p.6678-6680

1991

Volltextzugriff (PDF)

Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors

Journal of medicinal chemistry, 2009-02, Vol.52 (4), p.1156-1171

2009

Volltextzugriff (PDF)

Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model

Journal of medicinal chemistry, 2008-07, Vol.51 (14), p.4068

2008

Volltextzugriff (PDF)

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Bioorganic & medicinal chemistry, 2008-02, Vol.16 (3), p.1345

2008

Volltextzugriff (PDF)

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Use of dihydroxyacetone phosphate dependent aldolases in the synthesis of deoxyazasugars

Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α2α

β-C-Mannosides as Selectin Inhibitors

Deoxyribose 5-phosphate aldolase as a catalyst in asymmetric aldol condensation

Indole Cytosolic Phospholipase A2 α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid, Efipladib

Discovery of ecopladib, an indole inhibitor of cytosolic phospholipase A2α

Piperazine Sulfonamides as Potent, Selective, and Orally Available 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors with Efficacy in the Rat Cortisone-Induced Hyperinsulinemia Model

Reactions of Functionalized Sulfonamides: Application to Lowering the Lipophilicity of Cytosolic Phospholipase A 2 α Inhibitors

Enzymes in organic synthesis: synthesis of highly enantiomerically pure 1,2-epoxy aldehydes, epoxy alcohols, thiirane, aziridine, and glyceraldehyde 3-phosphate

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2α : Optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Reactions of Functionalized Sulfonamides: Application to Lowering the Lipophilicity of Cytosolic Phospholipase A2α Inhibitors

Indole Cytosolic Phospholipase A 2 α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1 H -indol-3-yl]propyl}benzoic Acid, Efipladib

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A 2α: Optimization of in vitro potency and rat pharmacokinetics for oral efficacy

Discovery of Ecopladib, an indole inhibitor of cytosolic phospholipase A2alpha

Discovery of Ecopladib, an Indole Inhibitor of Cytosolic Phospholipase Α 2 α

Recombinant 2-Deoxyribose-5-phosphate Aldolase in Organic Synthesis: Use of Sequential Two-Substrate and Three-Substrate Aldol Reactions

Indole Cytosolic Phospholipase A2 α Inhibitors : Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-l-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid, Efipladib

Palladium-mediated stereocontrolled reductive amination of azido sugars prepared from enzymic aldol condensation: a general approach to the synthesis of deoxy aza sugars

Synthesis of C1-C8 and C9-C24 fragments of (−)-discodermolide: use of asymmetric alkylation and stereoselective aldol reactions

Use of dihydroxyacetone phosphate-dependent aldolases in the synthesis of deoxy aza sugars

Enzymes for carbohydrate and peptide syntheses

Palladium-mediated stereocontrolled reductive amination of azido sugars prepared from enzymatic aldol condensation : a general approach to the synthesis of deoxy aza sugars

Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors

Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model

Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy

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