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Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (50), p.19796-19801

2007

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Klotho, PTSD, and advanced epigenetic age in cortical tissue

Neuropsychopharmacology (New York, N.Y.), 2021-03, Vol.46 (4), p.721-730

2021

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Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress

The FASEB journal, 2020-02, Vol.34 (2), p.2087-2104

2020

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A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone

The FASEB journal, 2020-06, Vol.34 (6), p.7234-7246

2020

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Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex

Journal of molecular neuroscience, 2018-02, Vol.64 (2), p.175-184

2018

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Cell‐type dependent modulation of Notch signaling by the amyloid precursor protein

Journal of neurochemistry, 2010-04, Vol.113 (1), p.262-274

2010

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The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System

The Journal of biological chemistry, 2014-08, Vol.289 (35), p.24700-24715

2014

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Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho

Biochemistry (Easton), 2014-09, Vol.53 (34), p.5579-5587

2014

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The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS

The Journal of neuroscience, 2013-01, Vol.33 (5), p.1927-1939

2013

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The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination

Journal of molecular neuroscience, 2015-10, Vol.57 (2), p.185-196

2015

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Age-dependent accumulation of ubiquitinated 2′,3′-cyclic nucleotide 3′-phosphodiesterase in myelin lipid rafts

Glia, 2008-01, Vol.56 (1), p.118-133

2008

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Visualization of APP dimerization and APP‐Notch2 heterodimerization in living cells using bimolecular fluorescence complementation

Journal of neurochemistry, 2006-04, Vol.97 (1), p.30-43

2006

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The Anti-Aging and Tumor Suppressor Protein Klotho Enhances Differentiation of a Human Oligodendrocytic Hybrid Cell Line

Journal of molecular neuroscience, 2015-01, Vol.55 (1), p.76-90

2015

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Gene Expression Changes Associated with the Endoplasmic Reticulum Stress Response Induced by Microsomal Cytochrome P450 Overproduction

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.13953-13961

2004

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Identification of the cleavage sites leading to the shed forms of human and mouse anti-aging and cognition-enhancing protein Klotho

PloS one, 2020, Vol.15 (1), p.e0226382

2020

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Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS

Journal of molecular neuroscience, 2019-10, Vol.69 (2), p.264-285

2019

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Amyloid precursor protein interacts with notch receptors

Journal of neuroscience research, 2005-10, Vol.82 (1), p.32-42

2005

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Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein

Molecular neurodegeneration, 2008-03, Vol.3 (1), p.5-5, Article 5

2008

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Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling

Journal of Alzheimer's disease, 2019-01, Vol.67 (3), p.1089

2019

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Furin initiates gelsolin familial amyloidosis in the Golgi through a defect in Ca2+ stabilization

The EMBO journal, 2001-11, Vol.20 (22), p.6277-6287

2001

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Different Structural Requirements at Specific Proline Residue Positions in the Conserved Proline-rich Region of Cytochrome P450 2C2

The Journal of biological chemistry, 1996-11, Vol.271 (45), p.28607-28611

1996

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Detection of amyloid-β protein precursor homo-interactions using beta-galactosidase enzyme fragment complementation

Journal of Alzheimer's disease, 2011-01, Vol.26 (4), p.647

2011

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The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum (∗)

The Journal of biological chemistry, 1995-10, Vol.270 (41), p.24327-24333

1995

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Stability of RNA from the Retina and Retinal Pigment Epithelium in a Porcine Model Simulating Human Eye Bank Conditions

Investigative ophthalmology & visual science, 2003-06, Vol.44 (6), p.2730-2735

2003

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A Conserved Proline-rich Sequence between the N-terminal Signal-anchor and Catalytic Domains Is Required for Assembly of Functional Cytochrome P450 2C2

Archives of biochemistry and biophysics, 1998-02, Vol.350 (2), p.233-238

1998

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Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17

Klotho, PTSD, and advanced epigenetic age in cortical tissue

Klotho regulation by albuminuria is dependent on ATF3 and endoplasmic reticulum stress

A method to specifically activate the Klotho promoter by using zinc finger proteins constructed from modular building blocks and from naturally engineered Egr1 transcription factor backbone

Activation of the Anti-Aging and Cognition-Enhancing Gene Klotho by CRISPR-dCas9 Transcriptional Effector Complex

Cell‐type dependent modulation of Notch signaling by the amyloid precursor protein

The Neuroprotective Effect of Klotho is Mediated via Regulation of Members of the Redox System

Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho

The antiaging protein Klotho enhances oligodendrocyte maturation and myelination of the CNS

The Anti-Aging Protein Klotho Enhances Remyelination Following Cuprizone-Induced Demyelination

Age-dependent accumulation of ubiquitinated 2′,3′-cyclic nucleotide 3′-phosphodiesterase in myelin lipid rafts

Visualization of APP dimerization and APP‐Notch2 heterodimerization in living cells using bimolecular fluorescence complementation

The Anti-Aging and Tumor Suppressor Protein Klotho Enhances Differentiation of a Human Oligodendrocytic Hybrid Cell Line

Gene Expression Changes Associated with the Endoplasmic Reticulum Stress Response Induced by Microsomal Cytochrome P450 Overproduction

Identification of the cleavage sites leading to the shed forms of human and mouse anti-aging and cognition-enhancing protein Klotho

Klotho Is Neuroprotective in the Superoxide Dismutase (SOD1G93A) Mouse Model of ALS

Amyloid precursor protein interacts with notch receptors

Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein

Small Molecule Amyloid-β Protein Precursor Processing Modulators Lower Amyloid-β Peptide Levels via cKit Signaling

Furin initiates gelsolin familial amyloidosis in the Golgi through a defect in Ca2+ stabilization

Different Structural Requirements at Specific Proline Residue Positions in the Conserved Proline-rich Region of Cytochrome P450 2C2

Detection of amyloid-β protein precursor homo-interactions using beta-galactosidase enzyme fragment complementation

The Cytoplasmic and N-terminal Transmembrane Domains of Cytochrome P450 Contain Independent Signals for Retention in the Endoplasmic Reticulum (∗)

Stability of RNA from the Retina and Retinal Pigment Epithelium in a Porcine Model Simulating Human Eye Bank Conditions

A Conserved Proline-rich Sequence between the N-terminal Signal-anchor and Catalytic Domains Is Required for Assembly of Functional Cytochrome P450 2C2

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