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Drug Discovery Strategies for SARS-CoV-2

The Journal of pharmacology and experimental therapeutics, 2020-10, Vol.375 (1), p.127

2020

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Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium

Cell stem cell, 2020-12, Vol.27 (6), p.937-950.e9

2020

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Influence of Equatorial and Axial Carboxylato Ligands on the Kinetic Inertness of Platinum(IV) Complexes in the Presence of Ascorbate and Cysteine and within DLD‑1 Cancer Cells

Journal of medicinal chemistry, 2013-11, Vol.56 (21), p.8757-8764

2013

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RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery

SLAS DISCOVERY: Advancing the Science of Drug Discovery, 2020-12, Vol.25 (10), p.1141-1151

2020

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Does Propofol Improve Polyp Detection during Colonoscopy? The Promise and Peril of Clinical Registry Data

Anesthesiology (Philadelphia), 2024-06, Vol.140 (6), p.1062

2024

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Warburg Effect Targeting Co(III) Cytotoxin Chaperone Complexes

Journal of medicinal chemistry, 2021-03, Vol.64 (5), p.2678-2690

2021

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Female toads engaging in adaptive hybridization prefer high-quality heterospecifics as mates

Science (American Association for the Advancement of Science), 2020-03, Vol.367 (6484), p.1377-1379

2020

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Identification of SARS-CoV‑2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening

ACS pharmacology & translational science, 2020-10, Vol.3 (5), p.1008-1016

2020

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Calling Out Aversive Racism in Academic Medicine

The New England journal of medicine, 2021-12, Vol.385 (27), p.2499-2501

2021

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Perioperative Risk Assessment and Avoiding Overuse of Anesthesia Care for Routine Cataract Surgery-Reply

JAMA internal medicine, 2023-05, Vol.183 (5), p.497

2023

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Efficient Identification of Anti-SARS-CoV‑2 Compounds Using Chemical Structure- and Biological Activity-Based Modeling

Journal of medicinal chemistry, 2022-03, Vol.65 (6), p.4590-4599

2022

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The Triple Bottom Line and Stabilization Wedges: A Framework for Perioperative Sustainability

Anesthesia and analgesia, 2022-03, Vol.134 (3), p.475-485

2022

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Synergistic and Antagonistic Drug Combinations against SARS-CoV-2

Molecular therapy, 2021-02, Vol.29 (2), p.873-885

2021

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The impact of highly electron withdrawing carboxylato ligands on the stability and activity of platinum(IV) pro-drugs

Inorganica Chimica Acta, 2019-08, Vol.494, p.84-90

2019

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Postoperative Respiratory Events in Surgical Patients Exposed to Opioid Analgesic Shortages Compared to Fully Matched Patients Non-exposed to Shortages

Drug safety, 2022-04, Vol.45 (4), p.359-367

2022

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Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation

Nature communications, 2023-09, Vol.14 (1), p.5777-5777, Article 5777

2023

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Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics

Scientific reports, 2021-03, Vol.11 (1), p.6725-6725, Article 6725

2021

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Preoperative Medical Testing in Medicare Patients Undergoing Cataract Surgery

The New England journal of medicine, 2015-04, Vol.372 (16), p.1530-1538

2015

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Postoperative thrombotic events following major surgery in patients with a history of COVID-19: a retrospective cohort analysis of commercially insured beneficiaries in the USA

Canadian journal of anesthesia, 2024-01, Vol.71 (1), p.55-65

2024

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Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

Emerging microbes & infections, 2014-12, Vol.3 (12), p.e84-7

2014

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Identification of SARS-CoV-2 viral entry inhibitors using machine learning and cell-based pseudotyped particle assay

Bioorganic & medicinal chemistry, 2021-05, Vol.38, p.116119-116119, Article 116119

2021

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Contemporary anesthesia practice for cataract surgery: analysis of the National Anesthesia Clinical Outcomes Registry

Journal of cataract and refractive surgery, 2022-12, Vol.48 (12), p.1472-1474

2022

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We Asked the Experts: Breaking the Cycle of Attrition in Perioperative Academic Medicine

World journal of surgery, 2021, Vol.45 (1), p.53-56

2021

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Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, a Potential Oral Drug Candidate for COVID-19 Treatment

Frontiers in pharmacology, 2022-08, Vol.13

2022

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Graph Convolutional Network-Based Screening Strategy for Rapid Identification of SARS-CoV‑2 Cell-Entry Inhibitors

Journal of chemical information and modeling, 2022-04, Vol.62 (8), p.1988-1997

2022

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Drug Discovery Strategies for SARS-CoV-2

Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium

Influence of Equatorial and Axial Carboxylato Ligands on the Kinetic Inertness of Platinum(IV) Complexes in the Presence of Ascorbate and Cysteine and within DLD‑1 Cancer Cells

RNA-Dependent RNA Polymerase as a Target for COVID-19 Drug Discovery

Does Propofol Improve Polyp Detection during Colonoscopy? The Promise and Peril of Clinical Registry Data

Warburg Effect Targeting Co(III) Cytotoxin Chaperone Complexes

Female toads engaging in adaptive hybridization prefer high-quality heterospecifics as mates

Identification of SARS-CoV‑2 3CL Protease Inhibitors by a Quantitative High-Throughput Screening

Calling Out Aversive Racism in Academic Medicine

Perioperative Risk Assessment and Avoiding Overuse of Anesthesia Care for Routine Cataract Surgery-Reply

Efficient Identification of Anti-SARS-CoV‑2 Compounds Using Chemical Structure- and Biological Activity-Based Modeling

The Triple Bottom Line and Stabilization Wedges: A Framework for Perioperative Sustainability

Synergistic and Antagonistic Drug Combinations against SARS-CoV-2

The impact of highly electron withdrawing carboxylato ligands on the stability and activity of platinum(IV) pro-drugs

Postoperative Respiratory Events in Surgical Patients Exposed to Opioid Analgesic Shortages Compared to Fully Matched Patients Non-exposed to Shortages

Host heparan sulfate promotes ACE2 super-cluster assembly and enhances SARS-CoV-2-associated syncytium formation

Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics

Preoperative Medical Testing in Medicare Patients Undergoing Cataract Surgery

Postoperative thrombotic events following major surgery in patients with a history of COVID-19: a retrospective cohort analysis of commercially insured beneficiaries in the USA

Identification of 53 compounds that block Ebola virus-like particle entry via a repurposing screen of approved drugs

Identification of SARS-CoV-2 viral entry inhibitors using machine learning and cell-based pseudotyped particle assay

Contemporary anesthesia practice for cataract surgery: analysis of the National Anesthesia Clinical Outcomes Registry

We Asked the Experts: Breaking the Cycle of Attrition in Perioperative Academic Medicine

Preclinical Pharmacokinetics and In Vitro Properties of GS-441524, a Potential Oral Drug Candidate for COVID-19 Treatment

Graph Convolutional Network-Based Screening Strategy for Rapid Identification of SARS-CoV‑2 Cell-Entry Inhibitors

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