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Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies

Biological research, 2021-08, Vol.54 (1), p.1-23, Article 23

2021

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Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways

The Journal of biological chemistry, 2011-05, Vol.286 (21), p.18465-18473

2011

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SERCA control of cell death and survival

Cell calcium (Edinburgh), 2018-01, Vol.69, p.46-61

2018

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Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis

Biochimica et biophysica acta. Molecular cell research, 2014-11, Vol.1843 (11), p.2705-2718

2014

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Molecular targets in heart failure gene therapy: current controversies and translational perspectives

Annals of the New York Academy of Sciences, 2012-04, Vol.1254 (1), p.42-50

2012

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Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins

Journal of molecular and cellular cardiology, 2007-04, Vol.42 (4), p.852-861

2007

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Stroke volume-to-wall stress ratio as a load-adjusted and stiffness-adjusted indicator of ventricular systolic performance in chronic loading

Journal of applied physiology (1985), 2012-10, Vol.113 (8), p.1267-1284

2012

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Comparison of Echocardiographic Measurements of Left Ventricular Volumes to Full Volume Magnetic Resonance Imaging in Normal and Diseased Rats

Journal of the American Society of Echocardiography, 2013-08, Vol.26 (8), p.910-918

2013

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Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a

PloS one, 2009-07, Vol.4 (7), p.e6474-e6474

2009

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Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a Type 2 diabetic rat model

American journal of physiology. Heart and circulatory physiology, 2007-02, Vol.292 (2), p.H1204-H1207

2007

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Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome

The Journal of clinical investigation, 2014-03, Vol.124 (3), p.1329-1329

2014

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Sarcoplasmic reticulum Ca2+ ATPase as a therapeutic target for heart failure

Expert opinion on biological therapy, 2010-01, Vol.10 (1), p.29-41

2010

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Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure

Expert opinion on biological therapy, 2010-01, Vol.10 (1), p.29-41

2010

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Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer

Molecular therapy, 2006-05, Vol.13 (5), p.987-996

2006

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Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts

American journal of physiology. Heart and circulatory physiology, 2007-05, Vol.292 (5), p.H2356-H2363

2007

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Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats

American journal of physiology. Heart and circulatory physiology, 2009-04, Vol.296 (4), p.H1117-H1124

2009

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Long-term in vivo resistin overexpression induces myocardial dysfunction and remodeling in rats

Journal of molecular and cellular cardiology, 2011-08, Vol.51 (2), p.144-155

2011

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Molecular targets of current and prospective heart failure therapies

Heart (British Cardiac Society), 2013-07, Vol.99 (14), p.992-1003

2013

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Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin

The Journal of physiology, 2013-11, Vol.591 (21), p.5337-5355

2013

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Assessing left ventricular systolic dysfunction after myocardial infarction: are ejection fraction and dP/dt(max) complementary or redundant?

American journal of physiology. Heart and circulatory physiology, 2012-04, Vol.302 (7), p.H1423

2012

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Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy

Biochimica et biophysica acta, 2015-11, Vol.1853 (11), p.2870-2884

2015

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Veverimer: an advance in base therapy for metabolic acidosis

Annals of translational medicine, 2020-10, Vol.8 (20), p.1331-1331

2020

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Mechanoelectrical remodeling and arrhythmias during progression of hypertrophy

The FASEB journal, 2010-02, Vol.24 (2), p.451-463

2010

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A new model of congestive heart failure in rats

American journal of physiology. Heart and circulatory physiology, 2011-09, Vol.301 (3), p.H994-H1003

2011

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PRESERVATION OF MECHANICAL AND ENERGETIC FUNCTION AFTER ADENOVIRAL GENE TRANSFER IN NORMAL RAT HEARTS

Clinical and experimental pharmacology & physiology, 2007-12, Vol.34 (12), p.1300-1306

2007

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Molecules linked to Ras signaling as therapeutic targets in cardiac pathologies

Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways

SERCA control of cell death and survival

Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis

Molecular targets in heart failure gene therapy: current controversies and translational perspectives

Restoration of mechanical and energetic function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins

Stroke volume-to-wall stress ratio as a load-adjusted and stiffness-adjusted indicator of ventricular systolic performance in chronic loading

Comparison of Echocardiographic Measurements of Left Ventricular Volumes to Full Volume Magnetic Resonance Imaging in Normal and Diseased Rats

Gene remodeling in type 2 diabetic cardiomyopathy and its phenotypic rescue with SERCA2a

Transcoronary gene transfer of SERCA2a increases coronary blood flow and decreases cardiomyocyte size in a Type 2 diabetic rat model

Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome

Sarcoplasmic reticulum Ca2+ ATPase as a therapeutic target for heart failure

Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure

Mechanical and metabolic rescue in a type II diabetes model of cardiomyopathy by targeted gene transfer

Targeted gene transfer increases contractility and decreases oxygen cost of contractility in normal rat hearts

Mechanical work and energetic analysis of eccentric cardiac remodeling in a volume overload heart failure in rats

Long-term in vivo resistin overexpression induces myocardial dysfunction and remodeling in rats

Molecular targets of current and prospective heart failure therapies

Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin

Assessing left ventricular systolic dysfunction after myocardial infarction: are ejection fraction and dP/dt(max) complementary or redundant?

Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy

Veverimer: an advance in base therapy for metabolic acidosis

Mechanoelectrical remodeling and arrhythmias during progression of hypertrophy

A new model of congestive heart failure in rats

PRESERVATION OF MECHANICAL AND ENERGETIC FUNCTION AFTER ADENOVIRAL GENE TRANSFER IN NORMAL RAT HEARTS

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