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A review of challenges and prospects of 3D cell-based culture models used for studying drug induced liver injury during early phases of drug development

Human & Experimental Toxicology, 2023-01, Vol.42, p.9603271221147884-9603271221147884

2023

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The Implication of Low Dose Dimethyl Sulfoxide on Mitochondrial Function and Oxidative Damage in Cultured Cardiac and Cancer Cells

Molecules (Basel, Switzerland), 2021-12, Vol.26 (23), p.7305

2021

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Non-communicable diseases - a catastrophe for South Africa

South African Journal of Science, 2021-05, Vol.117 (5-6), p.32-37

2021

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New Insights into the Efficacy of Aspalathin and Other Related Phytochemicals in Type 2 Diabetes-A Review

International journal of molecular sciences, 2021-12, Vol.23 (1), p.356

2021

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Diet-induced hypothalamic dysfunction and metabolic disease, and the therapeutic potential of polyphenols

Molecular metabolism (Germany), 2019-09, Vol.27, p.1-10

2019

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Aspalathin-Rich Green Rooibos Extract Lowers LDL-Cholesterol and Oxidative Status in High-Fat Diet-Induced Diabetic Vervet Monkeys

Molecules (Basel, Switzerland), 2019-05, Vol.24 (9), p.1713

2019

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Clinical use of N-acetyl cysteine during liver transplantation: Implications of oxidative stress and inflammation as therapeutic targets

Biomedicine & pharmacotherapy, 2022-03, Vol.147, p.112638-112638, Article 112638

2022

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Phenylpropenoic acid glucoside augments pancreatic beta cell mass in high‐fat diet‐fed mice and protects beta cells from ER stress‐induced apoptosis

Molecular nutrition & food research, 2014-10, Vol.58 (10), p.1980-1990

2014

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The Combination Effect of Aspalathin and Phenylpyruvic Acid-2- O -β-D-glucoside from Rooibos against Hyperglycemia-Induced Cardiac Damage: An In Vitro Study

Nutrients, 2020-04, Vol.12 (4), p.1151

2020

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Hypothalamic neurogenesis and its implications for obesity-induced anxiety disorders

Frontiers in neuroendocrinology, 2021-01, Vol.60, p.100871-100871, Article 100871

2021

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In vitro Characterization of Insulin-Producing β-Cell Spheroids

Frontiers in cell and developmental biology, 2021-01, Vol.8, p.623889-623889

2021

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Corrigendum: In vitro Characterization of Insulin-Producing β-Cell Spheroids

Frontiers in cell and developmental biology, 2021-03, Vol.9, p.662574-662574

2021

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The Effect of Metformin and Hydrochlorothiazide on Cytochrome P450 3A4 Metabolism of Ivermectin: Insights from In Silico Experimentation

International journal of molecular sciences, 2024-11, Vol.25 (22), p.12089

2024

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Potential of rooibos, its major C-glucosyl flavonoids, and Z-2-(β-D-glucopyranosyloxy)-3-phenylpropenoic acid in prevention of metabolic syndrome

Critical reviews in food science and nutrition, 2018-01, Vol.58 (2), p.227-246

2018

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Curcumin supplementation improves biomarkers of oxidative stress and inflammation in conditions of obesity, type 2 diabetes and NAFLD: updating the status of clinical evidence

Food & function, 2021-12, Vol.12 (24), p.12235-12249

2021

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Running with Type 1 Diabetes: A Case Report on the Benefit of Sensor Technology

Diabetology, 2022-06, Vol.3 (2), p.310-314

2022

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Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects

Oxidative medicine and cellular longevity, 2021, Vol.2021 (1), p.3320325-3320325

2021

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Vitamin K: A vital micronutrient with the cardioprotective potential against diabetes-associated complications

Life sciences (1973), 2021-12, Vol.286, p.120068-120068, Article 120068

2021

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In Vitro Antidiabetic, Antioxidant, and Cytotoxic Evaluation of Honeybush Tea (Cyclopia genistoides) Extracts

Journal of food biochemistry, 2023-06, Vol.2023, p.1-11

2023

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Green Rooibos Extract improves plasma lipid profile and oxidative status in diabetic non-human primates

Free radical biology & medicine, 2017-07, Vol.108, p.S97

2017

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P 228 - Green Rooibos Extract improves plasma lipid profile and oxidative status in diabetic non-human primates

Free radical biology & medicine, 2017-07, Vol.108, p.S97-S97

2017

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Antimycin A-induced mitochondrial dysfunction is consistent with impaired insulin signaling in cultured skeletal muscle cells

Toxicology in vitro, 2021-10, Vol.76, p.105224-105224, Article 105224

2021

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Fermented rooibos extract attenuates hyperglycemia-induced myocardial oxidative damage by improving mitochondrial energetics and intracellular antioxidant capacity

South African journal of botany, 2020-07, Vol.131, p.143-150

2020

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Palmitate-induced toxicity is associated with impaired mitochondrial respiration and accelerated oxidative stress in cultured cardiomyocytes: The critical role of coenzyme Q9/10

Toxicology in vitro, 2020-10, Vol.68, p.104948, Article 104948

2020

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Aqueous extract of unfermented honeybush (Cyclopia maculata) attenuates STZ-induced diabetes and β-cell cytotoxicity

Planta medica, 2014-06, Vol.80 (8-9), p.622-629

2014

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A review of challenges and prospects of 3D cell-based culture models used for studying drug induced liver injury during early phases of drug development

The Implication of Low Dose Dimethyl Sulfoxide on Mitochondrial Function and Oxidative Damage in Cultured Cardiac and Cancer Cells

Non-communicable diseases - a catastrophe for South Africa

New Insights into the Efficacy of Aspalathin and Other Related Phytochemicals in Type 2 Diabetes-A Review

Diet-induced hypothalamic dysfunction and metabolic disease, and the therapeutic potential of polyphenols

Aspalathin-Rich Green Rooibos Extract Lowers LDL-Cholesterol and Oxidative Status in High-Fat Diet-Induced Diabetic Vervet Monkeys

Clinical use of N-acetyl cysteine during liver transplantation: Implications of oxidative stress and inflammation as therapeutic targets

Phenylpropenoic acid glucoside augments pancreatic beta cell mass in high‐fat diet‐fed mice and protects beta cells from ER stress‐induced apoptosis

The Combination Effect of Aspalathin and Phenylpyruvic Acid-2- O -β-D-glucoside from Rooibos against Hyperglycemia-Induced Cardiac Damage: An In Vitro Study

Hypothalamic neurogenesis and its implications for obesity-induced anxiety disorders

In vitro Characterization of Insulin-Producing β-Cell Spheroids

Corrigendum: In vitro Characterization of Insulin-Producing β-Cell Spheroids

The Effect of Metformin and Hydrochlorothiazide on Cytochrome P450 3A4 Metabolism of Ivermectin: Insights from In Silico Experimentation

Potential of rooibos, its major C-glucosyl flavonoids, and Z-2-(β-D-glucopyranosyloxy)-3-phenylpropenoic acid in prevention of metabolic syndrome

Curcumin supplementation improves biomarkers of oxidative stress and inflammation in conditions of obesity, type 2 diabetes and NAFLD: updating the status of clinical evidence

Running with Type 1 Diabetes: A Case Report on the Benefit of Sensor Technology

Drug-Induced Liver Injury: Clinical Evidence of N-Acetyl Cysteine Protective Effects

Vitamin K: A vital micronutrient with the cardioprotective potential against diabetes-associated complications

In Vitro Antidiabetic, Antioxidant, and Cytotoxic Evaluation of Honeybush Tea (Cyclopia genistoides) Extracts

Green Rooibos Extract improves plasma lipid profile and oxidative status in diabetic non-human primates

P 228 - Green Rooibos Extract improves plasma lipid profile and oxidative status in diabetic non-human primates

Antimycin A-induced mitochondrial dysfunction is consistent with impaired insulin signaling in cultured skeletal muscle cells

Fermented rooibos extract attenuates hyperglycemia-induced myocardial oxidative damage by improving mitochondrial energetics and intracellular antioxidant capacity

Palmitate-induced toxicity is associated with impaired mitochondrial respiration and accelerated oxidative stress in cultured cardiomyocytes: The critical role of coenzyme Q9/10

Aqueous extract of unfermented honeybush (Cyclopia maculata) attenuates STZ-induced diabetes and β-cell cytotoxicity

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