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The utility of animal models to evaluate novel anti‐obesity agents

British journal of pharmacology, 2011-10, Vol.164 (4), p.1248-1262

2011

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Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility

Psychopharmacology, 2020-09, Vol.237 (9), p.2695-2707

2020

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Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet

Diabetes, metabolic syndrome and obesity, 2014-01, Vol.7 (default), p.265-275

2014

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Receptor occupancy and brain free fraction

Drug metabolism and disposition, 2009-04, Vol.37 (4), p.753-760

2009

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Characterisation of Pain Responses in the High Fat Diet/Streptozotocin Model of Diabetes and the Analgesic Effects of Antidiabetic Treatments

Journal of Diabetes Research, 2015-01, Vol.2015 (2015), p.1-13

2015

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Effect of linagliptin, alone and in combination with voglibose or exendin-4, on glucose control in male ZDF rats

European journal of pharmacology, 2014-04, Vol.729, p.59-66

2014

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Effects of corticosterone within the hypothalamic arcuate nucleus on food intake and body weight in male rats

Molecular metabolism (Germany), 2020-06, Vol.36, p.100972-100972, Article 100972

2020

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Prokineticin 2 Is a Hypothalamic Neuropeptide That Potently Inhibits Food Intake

Diabetes (New York, N.Y.), 2010-02, Vol.59 (2), p.397-406

2010

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FRI-304-Elafibranor and pioglitazone reduce NASH and fibrosis in a genetically-obese dietary-induced NASH mouse model

Journal of hepatology, 2019-04, Vol.70 (1), p.e529-e529

2019

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Dopamine, but not norepinephrine or serotonin, reuptake inhibition reverses motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates

The Journal of pharmacology and experimental therapeutics, 2002-12, Vol.303 (3), p.952-958

2002

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Dexamethasone and Enalaprilat but Not SB525334 Exhibit Anti-Inflammatory Properties in Precision-Cut Kidney Slices (PCKSs) Obtained from Mice with Adriamycin-Induced Nephropathy: SA-PO285

Journal of the American Society of Nephrology, 2023-11, Vol.34 (11S), p.802-802

2023

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Effects of the DPP-4 inhibitor, linagliptin, in diet-induced obese rats: a comparison in naive and exenatide-treated animals

Clinical laboratory (Heidelberg), 2012-01, Vol.58 (7-8), p.787

2012

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Metabolic consequences of antipsychotic therapy: preclinical and clinical perspectives on diabetes, diabetic ketoacidosis, and obesity

Handbook of experimental pharmacology, 2012 (212), p.135

2012

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Ex vivo receptor binding in rats as a rapid screen for CNS penetration and occupancy of abuse-related molecular targets

Journal of pharmacological and toxicological methods, 2020-09, Vol.105, p.106706, Article 106706

2020

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Comparison of the physical dependence syndromes produced in rats by morphine and diazepam

Journal of pharmacological and toxicological methods, 2019-09, Vol.99, p.106595, Article 106595

2019

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Histologic Characterization of Retina Neuroglia Modifications in Diabetic Zucker Diabetic Fatty Rats

Investigative ophthalmology & visual science, 2017-09, Vol.58 (11), p.4925-4933

2017

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GPR39 Signaling Is Stimulated by Zinc Ions But Not by Obestatin

Endocrinology (Philadelphia), 2007-01, Vol.148 (1), p.13-20

2007

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Reduced dopamine turnover in the basal ganglia of depressed suicides

Brain research, 1997-09, Vol.769 (1), p.135-140

1997

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The monoamine reuptake inhibitor BTS 74 398 fails to evoke established dyskinesia but does not synergise with levodopa in MPTP-treated primates

Movement disorders, 2004-01, Vol.19 (1), p.15-21

2004

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Dopamine and [mu]-opioid receptor dysregulation in the brains of binge-eating female rats - possible relevance in the psychopathology and treatment of binge-eating disorder

Journal of psychopharmacology (Oxford), 2017-06, Vol.31 (6), p.770

2017

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Dopamine reuptake inhibition and failure to evoke dyskinesia in MPTP-treated primates

European journal of pharmacology, 2002-09, Vol.451 (2), p.157-160

2002

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MTSEA prevents ligand binding to the human melanocortin-4 receptor by modification of cysteine 130 in transmembrane helix 3

FEBS letters, 2005-01, Vol.579 (1), p.285-291

2005

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Metabolic effects of the Cimicifuga racemosa extract Ze 450 in vitro and in ob/ob mice

Maturitas, 2017-06, Vol.100, p.139-139

2017

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A sustained release formulation of novel quininib-hyaluronan microneedles inhibits angiogenesis and retinal vascular permeability in vivo

Journal of controlled release, 2016-07, Vol.233, p.198-207

2016

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The utility of animal models to evaluate novel anti‐obesity agents

Novel, non-nitrocatechol catechol-O-methyltransferase inhibitors modulate dopamine neurotransmission in the frontal cortex and improve cognitive flexibility

Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model

Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet

Receptor occupancy and brain free fraction

Characterisation of Pain Responses in the High Fat Diet/Streptozotocin Model of Diabetes and the Analgesic Effects of Antidiabetic Treatments

Effect of linagliptin, alone and in combination with voglibose or exendin-4, on glucose control in male ZDF rats

Effects of corticosterone within the hypothalamic arcuate nucleus on food intake and body weight in male rats

Prokineticin 2 Is a Hypothalamic Neuropeptide That Potently Inhibits Food Intake

FRI-304-Elafibranor and pioglitazone reduce NASH and fibrosis in a genetically-obese dietary-induced NASH mouse model

Dopamine, but not norepinephrine or serotonin, reuptake inhibition reverses motor deficits in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates

Dexamethasone and Enalaprilat but Not SB525334 Exhibit Anti-Inflammatory Properties in Precision-Cut Kidney Slices (PCKSs) Obtained from Mice with Adriamycin-Induced Nephropathy: SA-PO285

Effects of the DPP-4 inhibitor, linagliptin, in diet-induced obese rats: a comparison in naive and exenatide-treated animals

Metabolic consequences of antipsychotic therapy: preclinical and clinical perspectives on diabetes, diabetic ketoacidosis, and obesity

Ex vivo receptor binding in rats as a rapid screen for CNS penetration and occupancy of abuse-related molecular targets

Comparison of the physical dependence syndromes produced in rats by morphine and diazepam

Histologic Characterization of Retina Neuroglia Modifications in Diabetic Zucker Diabetic Fatty Rats

GPR39 Signaling Is Stimulated by Zinc Ions But Not by Obestatin

Reduced dopamine turnover in the basal ganglia of depressed suicides

The monoamine reuptake inhibitor BTS 74 398 fails to evoke established dyskinesia but does not synergise with levodopa in MPTP-treated primates

Dopamine and [mu]-opioid receptor dysregulation in the brains of binge-eating female rats - possible relevance in the psychopathology and treatment of binge-eating disorder

Dopamine reuptake inhibition and failure to evoke dyskinesia in MPTP-treated primates

MTSEA prevents ligand binding to the human melanocortin-4 receptor by modification of cysteine 130 in transmembrane helix 3

Metabolic effects of the Cimicifuga racemosa extract Ze 450 in vitro and in ob/ob mice

A sustained release formulation of novel quininib-hyaluronan microneedles inhibits angiogenesis and retinal vascular permeability in vivo

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