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Accurate, fast, data efficient and interpretable glaucoma diagnosis with automated spatial analysis of the whole cup to disc profile

PloS one, 2019-01, Vol.14 (1), p.e0209409-e0209409

2019

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Correction: Accurate, fast, data efficient and interpretable glaucoma diagnosis with automated spatial analysis of the whole cup to disc profile

PloS one, 2019-04, Vol.14 (4), p.e0215056-e0215056

2019

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An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine‐56

Angewandte Chemie (International ed.), 2017-03, Vol.56 (13), p.3536-3540

International ed. in English, 2017

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Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen

Journal of medicinal chemistry, 2017-01, Vol.60 (1), p.180-201

2017

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Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4625-4636

2016

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Determination of Ligand-Binding Affinity (K d) Using Transverse Relaxation Rate (R 2) in the Ligand-Observed 1H NMR Experiment and Applications to Fragment-Based Drug Discovery

Journal of medicinal chemistry, 2023-08, Vol.66 (15), p.10617-10627

2023

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Determination of Ligand-Binding Affinity ( K d ) Using Transverse Relaxation Rate ( R 2 ) in the Ligand-Observed 1 H NMR Experiment and Applications to Fragment-Based Drug Discovery

Journal of medicinal chemistry, 2023-08, Vol.66 (15), p.10617-10627

2023

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A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms

Scientific reports, 2016-10, Vol.6 (1), p.34701-34701, Article 34701

2016

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Recycling disposable cups into paper plastic composites

Waste management (Elmsford), 2014-11, Vol.34 (11), p.2113-2119

2014

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Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1-aminopeptidase ERAP1

Bioorganic & medicinal chemistry letters, 2021-06, Vol.42, p.128050, Article 128050

2021

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Privileged Structures and Polypharmacology within and between Protein Families

ACS medicinal chemistry letters, 2018-12, Vol.9 (12), p.1199-1204

2018

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Randomised, open-label, phase II study of gemcitabine with and without IMM-101 for advanced pancreatic cancer

British journal of cancer, 2016-09, Vol.115 (7), p.789-796

2016

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Targeting the PPM1D phenotype; 2,4-bisarylthiazoles cause highly selective apoptosis in PPM1D amplified cell-lines

Bioorganic & medicinal chemistry letters, 2014-08, Vol.24 (15), p.3469-3474

2014

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Abstract 2976: Confirmation of in-cell target engagement using the proteolysis targeting chimeras (PROTACs) against pirin

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.2976-2976

2018

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Randomised, open-label, phase II study of gemcitabine with and without IMM-101 for advanced pancreatic cancer

British journal of cancer, 2016-10, Vol.115 (9), p.e16-e16

2016

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An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine‐56

Angewandte Chemie, 2017-03, Vol.129 (13), p.3590-3594

2017

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Erratum: Randomised, open-label, phase II study of gemcitabine with and without IMM-101 for advanced pancreatic cancer

British journal of cancer, 2016-10, Vol.115 (9), p.e16-e16

2016

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Prophylaxis with Weekly Versus Daily Fluconazole for Fungal Infections in Patients with AIDS

Clinical infectious diseases, 1998-12, Vol.27 (6), p.1369-1375

1998

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Accurate, fast, data efficient and interpretable glaucoma diagnosis with automated spatial analysis of the whole cup to disc profile

Correction: Accurate, fast, data efficient and interpretable glaucoma diagnosis with automated spatial analysis of the whole cup to disc profile

An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine‐56

Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen

Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70

Determination of Ligand-Binding Affinity (K d) Using Transverse Relaxation Rate (R 2) in the Ligand-Observed 1H NMR Experiment and Applications to Fragment-Based Drug Discovery

Determination of Ligand-Binding Affinity ( K d ) Using Transverse Relaxation Rate ( R 2 ) in the Ligand-Observed 1 H NMR Experiment and Applications to Fragment-Based Drug Discovery

A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms

Recycling disposable cups into paper plastic composites

Investigating the phosphinic acid tripeptide mimetic DG013A as a tool compound inhibitor of the M1-aminopeptidase ERAP1

Privileged Structures and Polypharmacology within and between Protein Families

Randomised, open-label, phase II study of gemcitabine with and without IMM-101 for advanced pancreatic cancer

Targeting the PPM1D phenotype; 2,4-bisarylthiazoles cause highly selective apoptosis in PPM1D amplified cell-lines

Abstract 2976: Confirmation of in-cell target engagement using the proteolysis targeting chimeras (PROTACs) against pirin

Randomised, open-label, phase II study of gemcitabine with and without IMM-101 for advanced pancreatic cancer

An Irreversible Inhibitor of HSP72 that Unexpectedly Targets Lysine‐56

Erratum: Randomised, open-label, phase II study of gemcitabine with and without IMM-101 for advanced pancreatic cancer

Prophylaxis with Weekly Versus Daily Fluconazole for Fungal Infections in Patients with AIDS

Non-Peptide Corticotropin-Releasing Hormone Antagonists: Syntheses and Structure−Activity Relationships of 2-Anilinopyrimidines and -triazines

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