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Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC−MS/MS

Analytical chemistry (Washington), 2003-07, Vol.75 (13), p.3019-3030

2003

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Validation of a microdose probe drug cocktail for clinical drug interaction assessments for drug transporters and CYP3A

Clinical pharmacology and therapeutics, 2017-04, Vol.101 (4), p.519-530

2017

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Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

Analytical chemistry (Washington), 1998-03, Vol.70 (5), p.882-889

1998

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Multiple-Dose Pharmacodynamics and Pharmacokinetics of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Subjects

Clinical pharmacology and therapeutics, 2008-12, Vol.84 (6), p.679-683

2008

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Determination of dextromethorphan and its metabolite dextrorphan in human urine using high performance liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry: a study of selectivity of a tandem mass spectrometric assay

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-02, Vol.816 (1), p.297-308

2005

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Quantitation of anacetrapib, stable-isotope labeled-anacetrapib (microdose), and four metabolites in human plasma using liquid chromatography tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2016-02, Vol.1011, p.204-214

2016

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Simultaneous determination of Aprepitant and two metabolites in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection

Journal of pharmaceutical and biomedical analysis, 2004-09, Vol.35 (5), p.1213-1229

2004

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High-performance liquid chromatographic–tandem mass spectrometric evaluation and determination of stable isotope labeled analogs of rofecoxib in human plasma samples from oral bioavailability studies

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002-02, Vol.767 (1), p.117-129

2002

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Determination of a novel substance P inhibitor in human plasma by high-performance liquid chromatography with atmospheric pressure chemical ionization mass spectrometric detection using single and triple quadrupole detectors

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004-08, Vol.807 (2), p.243-250

2004

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Quantitative liquid chromatographic and tandem mass spectrometric determination of vitamin D₃ in human serum with derivatization: A comparison of in-tube LLE, 96-well plate LLE and in-tip SPME

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-05, Vol.879 (17-18), p.1457-1466

2011

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Determination of efavirenz, a selective non-nucleoside reverse transcriptase inhibitor, in human plasma using HPLC with post-column photochemical derivatization and fluorescence detection

Journal of pharmaceutical and biomedical analysis, 2002-06, Vol.28 (5), p.925-934

2002

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Determination of a cyclooxygenase II inhibitor in human plasma by capillary gas chromatography with mass spectrometric detection

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004-06, Vol.805 (1), p.21-25

2004

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Determination of a thermally labile metabolite of a novel growth hormone secretagogue in human and dog plasma by liquid chromatography with ion spray tandem mass spectrometric detection

Journal of chromatography. B, Biomedical sciences and applications, 2001-08, Vol.760 (1), p.45-53

2001

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Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques

Drug metabolism and disposition, 2001-12, Vol.29 (12), p.1614

2001

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Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice

Drug metabolism and disposition, 2016-03, Vol.44 (3), p.428-434

2016

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Quantitative liquid chromatographic and tandem mass spectrometric determination of vitamin D 3 in human serum with derivatization: A comparison of in-tube LLE, 96-well plate LLE and in-tip SPME

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-05, Vol.879 (17), p.1457-1466

2011

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Cyclobenzaprine Pharmacokinetics, Including the Effects of Age, Gender, and Hepatic Insufficiency

Journal of clinical pharmacology, 2002-01, Vol.42 (1), p.61-69

2002

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Bioavailability of alendronate and vitamin D(3) in an alendronate/vitamin D(3) combination tablet

Journal of clinical pharmacology, 2011-10, Vol.51 (10), p.1439-1448

2011

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Determination of Rofecoxib (MK-0966), a cyclooxygenase-2 inhibitor, in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection

Journal of chromatography. B, Biomedical sciences and applications, 2000-10, Vol.748 (1), p.31-39

2000

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Development of high-performance liquid chromatography–tandem mass spectrometric methods for the determination of a new oxytocin receptor antagonist (L-368,899) extracted from human plasma and urine: a case of lack of specificity due to the presence of metabolites

Journal of chromatography. B, Biomedical sciences and applications, 1998-09, Vol.716 (1), p.195-208

1998

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Determination of a cyclic hexapeptide, a novel antifungal agent, in human plasma by high-performance liquid chromatography with ion spray and turbo ion spray tandem mass spectrometric detection

Journal of chromatography. B, Biomedical sciences and applications, 1999-01, Vol.721 (2), p.229-238

1999

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Updating Evidence for Cationization of Polymers in the Gas Phase during Matrix-Assisted Laser Desorption/Ionization

European journal of mass spectrometry (Chichester, England), 2005-02, Vol.11 (1), p.23-29

2005

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Quantitative liquid chromatographic and tandem mass spectrometric determination of vitamin D sub(3 in human serum with derivatization: A comparison of in-tube LLE, 96-well plate LLE and in-tip SPME)

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-05, Vol.879 (17-18), p.1457-1466

2011

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Disposition and pharmacokinetics of the antimigraine drug, rizatriptan, in humans

Drug metabolism and disposition, 2000-01, Vol.28 (1), p.89

2000

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Determination of a novel growth hormone secretagogue (MK-677) in human plasma at picogram levels by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry

Journal of chromatography. B, Biomedical sciences and applications, 1997-05, Vol.693 (1), p.131-137

1997

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Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC−MS/MS

Validation of a microdose probe drug cocktail for clinical drug interaction assessments for drug transporters and CYP3A

Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations

Multiple-Dose Pharmacodynamics and Pharmacokinetics of Anacetrapib, a Potent Cholesteryl Ester Transfer Protein (CETP) Inhibitor, in Healthy Subjects

Determination of dextromethorphan and its metabolite dextrorphan in human urine using high performance liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry: a study of selectivity of a tandem mass spectrometric assay

Quantitation of anacetrapib, stable-isotope labeled-anacetrapib (microdose), and four metabolites in human plasma using liquid chromatography tandem mass spectrometry

Simultaneous determination of Aprepitant and two metabolites in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection

High-performance liquid chromatographic–tandem mass spectrometric evaluation and determination of stable isotope labeled analogs of rofecoxib in human plasma samples from oral bioavailability studies

Determination of a novel substance P inhibitor in human plasma by high-performance liquid chromatography with atmospheric pressure chemical ionization mass spectrometric detection using single and triple quadrupole detectors

Quantitative liquid chromatographic and tandem mass spectrometric determination of vitamin D₃ in human serum with derivatization: A comparison of in-tube LLE, 96-well plate LLE and in-tip SPME

Determination of efavirenz, a selective non-nucleoside reverse transcriptase inhibitor, in human plasma using HPLC with post-column photochemical derivatization and fluorescence detection

Determination of a cyclooxygenase II inhibitor in human plasma by capillary gas chromatography with mass spectrometric detection

Determination of a thermally labile metabolite of a novel growth hormone secretagogue in human and dog plasma by liquid chromatography with ion spray tandem mass spectrometric detection

Mechanistic studies on the reversible metabolism of rofecoxib to 5-hydroxyrofecoxib in the rat: evidence for transient ring opening of a substituted 2-furanone derivative using stable isotope-labeling techniques

Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice

Quantitative liquid chromatographic and tandem mass spectrometric determination of vitamin D 3 in human serum with derivatization: A comparison of in-tube LLE, 96-well plate LLE and in-tip SPME

Cyclobenzaprine Pharmacokinetics, Including the Effects of Age, Gender, and Hepatic Insufficiency

Bioavailability of alendronate and vitamin D(3) in an alendronate/vitamin D(3) combination tablet

Determination of Rofecoxib (MK-0966), a cyclooxygenase-2 inhibitor, in human plasma by high-performance liquid chromatography with tandem mass spectrometric detection

Development of high-performance liquid chromatography–tandem mass spectrometric methods for the determination of a new oxytocin receptor antagonist (L-368,899) extracted from human plasma and urine: a case of lack of specificity due to the presence of metabolites

Determination of a cyclic hexapeptide, a novel antifungal agent, in human plasma by high-performance liquid chromatography with ion spray and turbo ion spray tandem mass spectrometric detection

Updating Evidence for Cationization of Polymers in the Gas Phase during Matrix-Assisted Laser Desorption/Ionization

Quantitative liquid chromatographic and tandem mass spectrometric determination of vitamin D sub(3 in human serum with derivatization: A comparison of in-tube LLE, 96-well plate LLE and in-tip SPME)

Disposition and pharmacokinetics of the antimigraine drug, rizatriptan, in humans

Determination of a novel growth hormone secretagogue (MK-677) in human plasma at picogram levels by liquid chromatography with atmospheric pressure chemical ionization tandem mass spectrometry

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